Influence of addition of [2-(methacryloyloxy)ethyl]trimethylammonium chloride to an experimental adhesive
Autor(a) principal: | |
---|---|
Data de Publicação: | 2017 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Brazilian Oral Research |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242017000100232 |
Resumo: | Abstract The aim of this study was to develop an experimental adhesive with addition of [2-(methacryloyloxy)ethyl]trimethylammonium chloride (METAC) and to evaluate its mechanical and biological properties and its in vitro antibacterial activity. An experimental adhesive resin was formulated with Bis-GMA, TEGDMA, and HEMA. The antibacterial monomer was added at concentrations of 1%, 2.5%, and 5% (METAC groups). A group without METAC addition was used as control. The experimental adhesives were evaluated as to their antibacterial potential against Streptococcus mutans, degree of conversion, and softening in ethanol for 2 hours. The data were analyzed by one-way ANOVA, Tukey’s post-hoc test, and the paired Student’s t-test (significance level of 0.05). METAC showed antibacterial activity against S. mutans at all concentrations (p < 0.05). There was no statistical difference across METAC groups (p > 0.05). The 1%, 2.5%, and 5% groups yielded the highest mean values for degree of conversion (p < 0.05). The 1% group did not differ from the control group (p > 0.05). There was no statistical difference in baseline microhardness values (p > 0.05) and microhardness values after immersion in ethanol were lower than at baseline for all groups (p < 0.05). There was no statistical difference in the reduction of Knoop hardness number (KHN) after immersion in ethanol for any of the groups (p > 0.05). The results of the present study indicate that METAC is a promising antibacterial agent when added to an adhesive system. |
id |
SBPQO-1_da9dee191923fc3f4a505dabe00b1cdb |
---|---|
oai_identifier_str |
oai:scielo:S1806-83242017000100232 |
network_acronym_str |
SBPQO-1 |
network_name_str |
Brazilian Oral Research |
repository_id_str |
|
spelling |
Influence of addition of [2-(methacryloyloxy)ethyl]trimethylammonium chloride to an experimental adhesiveAnti-infective AgentsAdhesivesDentin-Bonding AgentsAbstract The aim of this study was to develop an experimental adhesive with addition of [2-(methacryloyloxy)ethyl]trimethylammonium chloride (METAC) and to evaluate its mechanical and biological properties and its in vitro antibacterial activity. An experimental adhesive resin was formulated with Bis-GMA, TEGDMA, and HEMA. The antibacterial monomer was added at concentrations of 1%, 2.5%, and 5% (METAC groups). A group without METAC addition was used as control. The experimental adhesives were evaluated as to their antibacterial potential against Streptococcus mutans, degree of conversion, and softening in ethanol for 2 hours. The data were analyzed by one-way ANOVA, Tukey’s post-hoc test, and the paired Student’s t-test (significance level of 0.05). METAC showed antibacterial activity against S. mutans at all concentrations (p < 0.05). There was no statistical difference across METAC groups (p > 0.05). The 1%, 2.5%, and 5% groups yielded the highest mean values for degree of conversion (p < 0.05). The 1% group did not differ from the control group (p > 0.05). There was no statistical difference in baseline microhardness values (p > 0.05) and microhardness values after immersion in ethanol were lower than at baseline for all groups (p < 0.05). There was no statistical difference in the reduction of Knoop hardness number (KHN) after immersion in ethanol for any of the groups (p > 0.05). The results of the present study indicate that METAC is a promising antibacterial agent when added to an adhesive system.Sociedade Brasileira de Pesquisa Odontológica - SBPqO2017-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242017000100232Brazilian Oral Research v.31 2017reponame:Brazilian Oral Researchinstname:Sociedade Brasileira de Pesquisa Odontológica (SBPqO)instacron:SBPQO10.1590/1807-3107bor-2017.vol31.0031info:eu-repo/semantics/openAccessCOLLARES,Fabrício MezzomoLEITUNE,Vicente Castelo BrancoFRANKEN,PatríciaPAROLLO,Clarissa FatturiOGLIARI,Fabrício AuloSAMUEL,Susana Maria Wernereng2017-05-11T00:00:00Zoai:scielo:S1806-83242017000100232Revistahttps://www.scielo.br/j/bor/https://old.scielo.br/oai/scielo-oai.phppob@edu.usp.br||bor@sbpqo.org.br1807-31071806-8324opendoar:2017-05-11T00:00Brazilian Oral Research - Sociedade Brasileira de Pesquisa Odontológica (SBPqO)false |
dc.title.none.fl_str_mv |
Influence of addition of [2-(methacryloyloxy)ethyl]trimethylammonium chloride to an experimental adhesive |
title |
Influence of addition of [2-(methacryloyloxy)ethyl]trimethylammonium chloride to an experimental adhesive |
spellingShingle |
Influence of addition of [2-(methacryloyloxy)ethyl]trimethylammonium chloride to an experimental adhesive COLLARES,Fabrício Mezzomo Anti-infective Agents Adhesives Dentin-Bonding Agents |
title_short |
Influence of addition of [2-(methacryloyloxy)ethyl]trimethylammonium chloride to an experimental adhesive |
title_full |
Influence of addition of [2-(methacryloyloxy)ethyl]trimethylammonium chloride to an experimental adhesive |
title_fullStr |
Influence of addition of [2-(methacryloyloxy)ethyl]trimethylammonium chloride to an experimental adhesive |
title_full_unstemmed |
Influence of addition of [2-(methacryloyloxy)ethyl]trimethylammonium chloride to an experimental adhesive |
title_sort |
Influence of addition of [2-(methacryloyloxy)ethyl]trimethylammonium chloride to an experimental adhesive |
author |
COLLARES,Fabrício Mezzomo |
author_facet |
COLLARES,Fabrício Mezzomo LEITUNE,Vicente Castelo Branco FRANKEN,Patrícia PAROLLO,Clarissa Fatturi OGLIARI,Fabrício Aulo SAMUEL,Susana Maria Werner |
author_role |
author |
author2 |
LEITUNE,Vicente Castelo Branco FRANKEN,Patrícia PAROLLO,Clarissa Fatturi OGLIARI,Fabrício Aulo SAMUEL,Susana Maria Werner |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
COLLARES,Fabrício Mezzomo LEITUNE,Vicente Castelo Branco FRANKEN,Patrícia PAROLLO,Clarissa Fatturi OGLIARI,Fabrício Aulo SAMUEL,Susana Maria Werner |
dc.subject.por.fl_str_mv |
Anti-infective Agents Adhesives Dentin-Bonding Agents |
topic |
Anti-infective Agents Adhesives Dentin-Bonding Agents |
description |
Abstract The aim of this study was to develop an experimental adhesive with addition of [2-(methacryloyloxy)ethyl]trimethylammonium chloride (METAC) and to evaluate its mechanical and biological properties and its in vitro antibacterial activity. An experimental adhesive resin was formulated with Bis-GMA, TEGDMA, and HEMA. The antibacterial monomer was added at concentrations of 1%, 2.5%, and 5% (METAC groups). A group without METAC addition was used as control. The experimental adhesives were evaluated as to their antibacterial potential against Streptococcus mutans, degree of conversion, and softening in ethanol for 2 hours. The data were analyzed by one-way ANOVA, Tukey’s post-hoc test, and the paired Student’s t-test (significance level of 0.05). METAC showed antibacterial activity against S. mutans at all concentrations (p < 0.05). There was no statistical difference across METAC groups (p > 0.05). The 1%, 2.5%, and 5% groups yielded the highest mean values for degree of conversion (p < 0.05). The 1% group did not differ from the control group (p > 0.05). There was no statistical difference in baseline microhardness values (p > 0.05) and microhardness values after immersion in ethanol were lower than at baseline for all groups (p < 0.05). There was no statistical difference in the reduction of Knoop hardness number (KHN) after immersion in ethanol for any of the groups (p > 0.05). The results of the present study indicate that METAC is a promising antibacterial agent when added to an adhesive system. |
publishDate |
2017 |
dc.date.none.fl_str_mv |
2017-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242017000100232 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242017000100232 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/1807-3107bor-2017.vol31.0031 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Pesquisa Odontológica - SBPqO |
publisher.none.fl_str_mv |
Sociedade Brasileira de Pesquisa Odontológica - SBPqO |
dc.source.none.fl_str_mv |
Brazilian Oral Research v.31 2017 reponame:Brazilian Oral Research instname:Sociedade Brasileira de Pesquisa Odontológica (SBPqO) instacron:SBPQO |
instname_str |
Sociedade Brasileira de Pesquisa Odontológica (SBPqO) |
instacron_str |
SBPQO |
institution |
SBPQO |
reponame_str |
Brazilian Oral Research |
collection |
Brazilian Oral Research |
repository.name.fl_str_mv |
Brazilian Oral Research - Sociedade Brasileira de Pesquisa Odontológica (SBPqO) |
repository.mail.fl_str_mv |
pob@edu.usp.br||bor@sbpqo.org.br |
_version_ |
1750318325265596416 |