Pulmonary arteriovenous malformations: diagnostic and treatment characteristics

Detalhes bibliográficos
Autor(a) principal: Salibe-Filho,William
Data de Publicação: 2019
Outros Autores: Piloto,Bruna Mamprim, Oliveira,Ellen Pierre de, Castro,Marcela Araújo, Affonso,Breno Boueri, Motta-Leal-Filho,Joaquim Maurício da, Bortolini,Edgar, Terra-Filho,Mário
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Jornal Brasileiro de Pneumologia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-37132019000400201
Resumo: ABSTRACT Objective: To present a case series of pulmonary arteriovenous malformations (PAVMs), describing the main clinical findings, the number/location of pulmonary vascular abnormalities, the clinical complications, and the treatment administered. Methods: This was a retrospective observational study evaluating patients with PAVM divided into two groups: hereditary hemorrhagic telangiectasia (HHT); and idiopathic PAVM (iPAVM). Results: A total of 41 patients were selected for inclusion, but only 33 had PAVMs. After clinical evaluation, 27 and 6 were diagnosed with HHT and iPAVM, respectively. In the HHT group, the mean age was 49.6 years and 88.9% were female. In that group, 4 patients had an SpO2 of < 90% and the most common clinical finding was epistaxis. In the iPAVM group, the mean age was 48.1 years and 83.3% were female. In that group, 3 patients had an SpO2 of < 90%. Computed tomographic pulmonary angiography showed that most of the PAVMs were in the lower lobes: 56.4% in the HHT group and 85.7% in the iPAVM group. Embolization was performed in 23 patients (in both groups). At this writing, 10 patients are scheduled to undergo the procedure. One of the patients who underwent embolization was subsequently referred for pulmonary resection. Conclusions: In both of the PAVM groups, there was a predominance of women and of fistulas located in the lower lobes. Few of the patients had respiratory symptoms, and most had an SpO2 > 90%. The treatment chosen for all patients was percutaneous transcatheter embolization.
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spelling Pulmonary arteriovenous malformations: diagnostic and treatment characteristicsTelangiectasia, hereditary hemorrhagicArteriovenous malformations/diagnosisArteriovenous malformations/therapyABSTRACT Objective: To present a case series of pulmonary arteriovenous malformations (PAVMs), describing the main clinical findings, the number/location of pulmonary vascular abnormalities, the clinical complications, and the treatment administered. Methods: This was a retrospective observational study evaluating patients with PAVM divided into two groups: hereditary hemorrhagic telangiectasia (HHT); and idiopathic PAVM (iPAVM). Results: A total of 41 patients were selected for inclusion, but only 33 had PAVMs. After clinical evaluation, 27 and 6 were diagnosed with HHT and iPAVM, respectively. In the HHT group, the mean age was 49.6 years and 88.9% were female. In that group, 4 patients had an SpO2 of < 90% and the most common clinical finding was epistaxis. In the iPAVM group, the mean age was 48.1 years and 83.3% were female. In that group, 3 patients had an SpO2 of < 90%. Computed tomographic pulmonary angiography showed that most of the PAVMs were in the lower lobes: 56.4% in the HHT group and 85.7% in the iPAVM group. Embolization was performed in 23 patients (in both groups). At this writing, 10 patients are scheduled to undergo the procedure. One of the patients who underwent embolization was subsequently referred for pulmonary resection. Conclusions: In both of the PAVM groups, there was a predominance of women and of fistulas located in the lower lobes. Few of the patients had respiratory symptoms, and most had an SpO2 > 90%. The treatment chosen for all patients was percutaneous transcatheter embolization.Sociedade Brasileira de Pneumologia e Tisiologia2019-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-37132019000400201Jornal Brasileiro de Pneumologia v.45 n.4 2019reponame:Jornal Brasileiro de Pneumologia (Online)instname:Sociedade Brasileira de Pneumologia e Tisiologia (SBPT)instacron:SBPT10.1590/1806-3713/e20180137info:eu-repo/semantics/openAccessSalibe-Filho,WilliamPiloto,Bruna MamprimOliveira,Ellen Pierre deCastro,Marcela AraújoAffonso,Breno BoueriMotta-Leal-Filho,Joaquim Maurício daBortolini,EdgarTerra-Filho,Márioeng2019-06-17T00:00:00Zoai:scielo:S1806-37132019000400201Revistahttp://www.jornaldepneumologia.com.br/default.aspONGhttps://old.scielo.br/oai/scielo-oai.php||jbp@jbp.org.br|| jpneumo@jornaldepneumologia.com.br1806-37561806-3713opendoar:2019-06-17T00:00Jornal Brasileiro de Pneumologia (Online) - Sociedade Brasileira de Pneumologia e Tisiologia (SBPT)false
dc.title.none.fl_str_mv Pulmonary arteriovenous malformations: diagnostic and treatment characteristics
title Pulmonary arteriovenous malformations: diagnostic and treatment characteristics
spellingShingle Pulmonary arteriovenous malformations: diagnostic and treatment characteristics
Salibe-Filho,William
Telangiectasia, hereditary hemorrhagic
Arteriovenous malformations/diagnosis
Arteriovenous malformations/therapy
title_short Pulmonary arteriovenous malformations: diagnostic and treatment characteristics
title_full Pulmonary arteriovenous malformations: diagnostic and treatment characteristics
title_fullStr Pulmonary arteriovenous malformations: diagnostic and treatment characteristics
title_full_unstemmed Pulmonary arteriovenous malformations: diagnostic and treatment characteristics
title_sort Pulmonary arteriovenous malformations: diagnostic and treatment characteristics
author Salibe-Filho,William
author_facet Salibe-Filho,William
Piloto,Bruna Mamprim
Oliveira,Ellen Pierre de
Castro,Marcela Araújo
Affonso,Breno Boueri
Motta-Leal-Filho,Joaquim Maurício da
Bortolini,Edgar
Terra-Filho,Mário
author_role author
author2 Piloto,Bruna Mamprim
Oliveira,Ellen Pierre de
Castro,Marcela Araújo
Affonso,Breno Boueri
Motta-Leal-Filho,Joaquim Maurício da
Bortolini,Edgar
Terra-Filho,Mário
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Salibe-Filho,William
Piloto,Bruna Mamprim
Oliveira,Ellen Pierre de
Castro,Marcela Araújo
Affonso,Breno Boueri
Motta-Leal-Filho,Joaquim Maurício da
Bortolini,Edgar
Terra-Filho,Mário
dc.subject.por.fl_str_mv Telangiectasia, hereditary hemorrhagic
Arteriovenous malformations/diagnosis
Arteriovenous malformations/therapy
topic Telangiectasia, hereditary hemorrhagic
Arteriovenous malformations/diagnosis
Arteriovenous malformations/therapy
description ABSTRACT Objective: To present a case series of pulmonary arteriovenous malformations (PAVMs), describing the main clinical findings, the number/location of pulmonary vascular abnormalities, the clinical complications, and the treatment administered. Methods: This was a retrospective observational study evaluating patients with PAVM divided into two groups: hereditary hemorrhagic telangiectasia (HHT); and idiopathic PAVM (iPAVM). Results: A total of 41 patients were selected for inclusion, but only 33 had PAVMs. After clinical evaluation, 27 and 6 were diagnosed with HHT and iPAVM, respectively. In the HHT group, the mean age was 49.6 years and 88.9% were female. In that group, 4 patients had an SpO2 of < 90% and the most common clinical finding was epistaxis. In the iPAVM group, the mean age was 48.1 years and 83.3% were female. In that group, 3 patients had an SpO2 of < 90%. Computed tomographic pulmonary angiography showed that most of the PAVMs were in the lower lobes: 56.4% in the HHT group and 85.7% in the iPAVM group. Embolization was performed in 23 patients (in both groups). At this writing, 10 patients are scheduled to undergo the procedure. One of the patients who underwent embolization was subsequently referred for pulmonary resection. Conclusions: In both of the PAVM groups, there was a predominance of women and of fistulas located in the lower lobes. Few of the patients had respiratory symptoms, and most had an SpO2 > 90%. The treatment chosen for all patients was percutaneous transcatheter embolization.
publishDate 2019
dc.date.none.fl_str_mv 2019-01-01
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dc.relation.none.fl_str_mv 10.1590/1806-3713/e20180137
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dc.publisher.none.fl_str_mv Sociedade Brasileira de Pneumologia e Tisiologia
publisher.none.fl_str_mv Sociedade Brasileira de Pneumologia e Tisiologia
dc.source.none.fl_str_mv Jornal Brasileiro de Pneumologia v.45 n.4 2019
reponame:Jornal Brasileiro de Pneumologia (Online)
instname:Sociedade Brasileira de Pneumologia e Tisiologia (SBPT)
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instname_str Sociedade Brasileira de Pneumologia e Tisiologia (SBPT)
instacron_str SBPT
institution SBPT
reponame_str Jornal Brasileiro de Pneumologia (Online)
collection Jornal Brasileiro de Pneumologia (Online)
repository.name.fl_str_mv Jornal Brasileiro de Pneumologia (Online) - Sociedade Brasileira de Pneumologia e Tisiologia (SBPT)
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