Nocturnal hypoxemia in children and adolescents with cystic fibrosis
Autor(a) principal: | |
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Data de Publicação: | 2013 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Jornal Brasileiro de Pneumologia (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-37132013000600667 |
Resumo: | OBJECTIVE: To determine the prevalence of nocturnal hypoxemia and its association with pulmonary function, nutritional status, sleep macrostructure, and obstructive respiratory events during sleep in a population of clinically stable children and adolescents with cystic fibrosis (CF).METHODS: This was a cross-sectional study involving 67 children and adolescents with CF between 2 and 14 years of age. All of the participants underwent polysomnography, and SpO2 was measured by pulse oximetry. We also evaluated the Shwachman-Kulczycki (S-K) scores, spirometry findings, and nutritional status of the patients.RESULTS: The study involved 67 patients. The mean age of the patients was 8 years. The S-K scores differed significantly between the patients with and without nocturnal hypoxemia, which was defined as an SpO2 < 90% for more than 5% of the total sleep time (73.75 ± 6.29 vs. 86.38 ± 8.70; p < 0.01). Nocturnal hypoxemia correlated with the severity of lung disease, FEV1 (rs= −0.42; p = 0.01), FVC (rs= −0.46; p = 0.01), microarousal index (rs= 0.32; p = 0.01), and apnea-hypopnea index (rs = 0.56; p = 0.01).CONCLUSIONS: In this sample of patients with CF and mild-to-moderate lung disease, nocturnal oxygenation correlated with the S-K score, spirometry variables, sleep macrostructure variables, and the apnea-hypopnea index. |
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Jornal Brasileiro de Pneumologia (Online) |
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Nocturnal hypoxemia in children and adolescents with cystic fibrosisCystic fibrosisSleepOximetryOBJECTIVE: To determine the prevalence of nocturnal hypoxemia and its association with pulmonary function, nutritional status, sleep macrostructure, and obstructive respiratory events during sleep in a population of clinically stable children and adolescents with cystic fibrosis (CF).METHODS: This was a cross-sectional study involving 67 children and adolescents with CF between 2 and 14 years of age. All of the participants underwent polysomnography, and SpO2 was measured by pulse oximetry. We also evaluated the Shwachman-Kulczycki (S-K) scores, spirometry findings, and nutritional status of the patients.RESULTS: The study involved 67 patients. The mean age of the patients was 8 years. The S-K scores differed significantly between the patients with and without nocturnal hypoxemia, which was defined as an SpO2 < 90% for more than 5% of the total sleep time (73.75 ± 6.29 vs. 86.38 ± 8.70; p < 0.01). Nocturnal hypoxemia correlated with the severity of lung disease, FEV1 (rs= −0.42; p = 0.01), FVC (rs= −0.46; p = 0.01), microarousal index (rs= 0.32; p = 0.01), and apnea-hypopnea index (rs = 0.56; p = 0.01).CONCLUSIONS: In this sample of patients with CF and mild-to-moderate lung disease, nocturnal oxygenation correlated with the S-K score, spirometry variables, sleep macrostructure variables, and the apnea-hypopnea index.Sociedade Brasileira de Pneumologia e Tisiologia2013-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-37132013000600667Jornal Brasileiro de Pneumologia v.39 n.6 2013reponame:Jornal Brasileiro de Pneumologia (Online)instname:Sociedade Brasileira de Pneumologia e Tisiologia (SBPT)instacron:SBPT10.1590/S1806-37132013000600005info:eu-repo/semantics/openAccessRamos,Regina Terse TrindadeSantana,Maria Angélica PinheiroAlmeida,Priscila de CarvalhoMachado Júnior,Almério de SouzaAraújo-Filho,José BouzasSalles,Cristinaeng2015-10-27T00:00:00Zoai:scielo:S1806-37132013000600667Revistahttp://www.jornaldepneumologia.com.br/default.aspONGhttps://old.scielo.br/oai/scielo-oai.php||jbp@jbp.org.br|| jpneumo@jornaldepneumologia.com.br1806-37561806-3713opendoar:2015-10-27T00:00Jornal Brasileiro de Pneumologia (Online) - Sociedade Brasileira de Pneumologia e Tisiologia (SBPT)false |
dc.title.none.fl_str_mv |
Nocturnal hypoxemia in children and adolescents with cystic fibrosis |
title |
Nocturnal hypoxemia in children and adolescents with cystic fibrosis |
spellingShingle |
Nocturnal hypoxemia in children and adolescents with cystic fibrosis Ramos,Regina Terse Trindade Cystic fibrosis Sleep Oximetry |
title_short |
Nocturnal hypoxemia in children and adolescents with cystic fibrosis |
title_full |
Nocturnal hypoxemia in children and adolescents with cystic fibrosis |
title_fullStr |
Nocturnal hypoxemia in children and adolescents with cystic fibrosis |
title_full_unstemmed |
Nocturnal hypoxemia in children and adolescents with cystic fibrosis |
title_sort |
Nocturnal hypoxemia in children and adolescents with cystic fibrosis |
author |
Ramos,Regina Terse Trindade |
author_facet |
Ramos,Regina Terse Trindade Santana,Maria Angélica Pinheiro Almeida,Priscila de Carvalho Machado Júnior,Almério de Souza Araújo-Filho,José Bouzas Salles,Cristina |
author_role |
author |
author2 |
Santana,Maria Angélica Pinheiro Almeida,Priscila de Carvalho Machado Júnior,Almério de Souza Araújo-Filho,José Bouzas Salles,Cristina |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Ramos,Regina Terse Trindade Santana,Maria Angélica Pinheiro Almeida,Priscila de Carvalho Machado Júnior,Almério de Souza Araújo-Filho,José Bouzas Salles,Cristina |
dc.subject.por.fl_str_mv |
Cystic fibrosis Sleep Oximetry |
topic |
Cystic fibrosis Sleep Oximetry |
description |
OBJECTIVE: To determine the prevalence of nocturnal hypoxemia and its association with pulmonary function, nutritional status, sleep macrostructure, and obstructive respiratory events during sleep in a population of clinically stable children and adolescents with cystic fibrosis (CF).METHODS: This was a cross-sectional study involving 67 children and adolescents with CF between 2 and 14 years of age. All of the participants underwent polysomnography, and SpO2 was measured by pulse oximetry. We also evaluated the Shwachman-Kulczycki (S-K) scores, spirometry findings, and nutritional status of the patients.RESULTS: The study involved 67 patients. The mean age of the patients was 8 years. The S-K scores differed significantly between the patients with and without nocturnal hypoxemia, which was defined as an SpO2 < 90% for more than 5% of the total sleep time (73.75 ± 6.29 vs. 86.38 ± 8.70; p < 0.01). Nocturnal hypoxemia correlated with the severity of lung disease, FEV1 (rs= −0.42; p = 0.01), FVC (rs= −0.46; p = 0.01), microarousal index (rs= 0.32; p = 0.01), and apnea-hypopnea index (rs = 0.56; p = 0.01).CONCLUSIONS: In this sample of patients with CF and mild-to-moderate lung disease, nocturnal oxygenation correlated with the S-K score, spirometry variables, sleep macrostructure variables, and the apnea-hypopnea index. |
publishDate |
2013 |
dc.date.none.fl_str_mv |
2013-12-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-37132013000600667 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-37132013000600667 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S1806-37132013000600005 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Pneumologia e Tisiologia |
publisher.none.fl_str_mv |
Sociedade Brasileira de Pneumologia e Tisiologia |
dc.source.none.fl_str_mv |
Jornal Brasileiro de Pneumologia v.39 n.6 2013 reponame:Jornal Brasileiro de Pneumologia (Online) instname:Sociedade Brasileira de Pneumologia e Tisiologia (SBPT) instacron:SBPT |
instname_str |
Sociedade Brasileira de Pneumologia e Tisiologia (SBPT) |
instacron_str |
SBPT |
institution |
SBPT |
reponame_str |
Jornal Brasileiro de Pneumologia (Online) |
collection |
Jornal Brasileiro de Pneumologia (Online) |
repository.name.fl_str_mv |
Jornal Brasileiro de Pneumologia (Online) - Sociedade Brasileira de Pneumologia e Tisiologia (SBPT) |
repository.mail.fl_str_mv |
||jbp@jbp.org.br|| jpneumo@jornaldepneumologia.com.br |
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1750318345853337600 |