Treatment compliance of patients with paracoccidioidomycosis in Central-West Brazil

Detalhes bibliográficos
Autor(a) principal: Andrade,Ursulla Vilella
Data de Publicação: 2019
Outros Autores: Oliveira,Sandra Maria do Valle Leone de, Chang,Marilene Rodrigues, Pereira,Edy Firmina, Marques,Ana Paula da Costa, Carvalho,Lidia Raquel de, Mendes,Rinaldo Poncio, Paniago,Anamaria Mello Miranda
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Jornal Brasileiro de Pneumologia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-37132019000200202
Resumo: ABSTRACT Objective: To evaluate the treatment compliance of patients with paracoccidioidomycosis. Methods: We studied 188 patients with paracoccidioidomycosis admitted to a tertiary referral hospital in the Central-West Region of Brazil from 2000 to 2010, to assess their compliance to treatment. In order to be considered compliant, patients needed to present two established criteria: (1) receive medicines from the pharmacy, and (2) achieve a self-reported utilization of at least 80% of the dispensed antifungal compounds prescribed since their previous appointment. Results: Most patients were male (95.7%), had the chronic form of the disease (94.2%), and were treated with cotrimoxazole (86.2%). Only 44.6% of patients were treatment compliant. The highest loss to follow-up was observed in the first 4 months of treatment (p < 0.02). Treatment compliance was higher for patients with than for those without pulmonary involvement (OR: 2.986; 95%CI 1.351-6.599), and higher for patients with than without tuberculosis as co-morbidity (OR: 2.763; 95%CI 1.004-7.604). Conclusions: Compliance to paracoccidioidomycosis treatment was low, and the period with the highest loss to follow-up corresponds to the first four months. Pulmonary paracoccidioidal involvement or tuberculosis comorbidity predicts a higher compliance to paracoccidioidomycosis therapy.
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spelling Treatment compliance of patients with paracoccidioidomycosis in Central-West BrazilParacoccidioidomycosisTreatment adherence and complianceloss to follow-upmycosesABSTRACT Objective: To evaluate the treatment compliance of patients with paracoccidioidomycosis. Methods: We studied 188 patients with paracoccidioidomycosis admitted to a tertiary referral hospital in the Central-West Region of Brazil from 2000 to 2010, to assess their compliance to treatment. In order to be considered compliant, patients needed to present two established criteria: (1) receive medicines from the pharmacy, and (2) achieve a self-reported utilization of at least 80% of the dispensed antifungal compounds prescribed since their previous appointment. Results: Most patients were male (95.7%), had the chronic form of the disease (94.2%), and were treated with cotrimoxazole (86.2%). Only 44.6% of patients were treatment compliant. The highest loss to follow-up was observed in the first 4 months of treatment (p < 0.02). Treatment compliance was higher for patients with than for those without pulmonary involvement (OR: 2.986; 95%CI 1.351-6.599), and higher for patients with than without tuberculosis as co-morbidity (OR: 2.763; 95%CI 1.004-7.604). Conclusions: Compliance to paracoccidioidomycosis treatment was low, and the period with the highest loss to follow-up corresponds to the first four months. Pulmonary paracoccidioidal involvement or tuberculosis comorbidity predicts a higher compliance to paracoccidioidomycosis therapy.Sociedade Brasileira de Pneumologia e Tisiologia2019-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-37132019000200202Jornal Brasileiro de Pneumologia v.45 n.2 2019reponame:Jornal Brasileiro de Pneumologia (Online)instname:Sociedade Brasileira de Pneumologia e Tisiologia (SBPT)instacron:SBPT10.1590/1806-3713/e20180167info:eu-repo/semantics/openAccessAndrade,Ursulla VilellaOliveira,Sandra Maria do Valle Leone deChang,Marilene RodriguesPereira,Edy FirminaMarques,Ana Paula da CostaCarvalho,Lidia Raquel deMendes,Rinaldo PoncioPaniago,Anamaria Mello Mirandaeng2019-04-15T00:00:00Zoai:scielo:S1806-37132019000200202Revistahttp://www.jornaldepneumologia.com.br/default.aspONGhttps://old.scielo.br/oai/scielo-oai.php||jbp@jbp.org.br|| jpneumo@jornaldepneumologia.com.br1806-37561806-3713opendoar:2019-04-15T00:00Jornal Brasileiro de Pneumologia (Online) - Sociedade Brasileira de Pneumologia e Tisiologia (SBPT)false
dc.title.none.fl_str_mv Treatment compliance of patients with paracoccidioidomycosis in Central-West Brazil
title Treatment compliance of patients with paracoccidioidomycosis in Central-West Brazil
spellingShingle Treatment compliance of patients with paracoccidioidomycosis in Central-West Brazil
Andrade,Ursulla Vilella
Paracoccidioidomycosis
Treatment adherence and compliance
loss to follow-up
mycoses
title_short Treatment compliance of patients with paracoccidioidomycosis in Central-West Brazil
title_full Treatment compliance of patients with paracoccidioidomycosis in Central-West Brazil
title_fullStr Treatment compliance of patients with paracoccidioidomycosis in Central-West Brazil
title_full_unstemmed Treatment compliance of patients with paracoccidioidomycosis in Central-West Brazil
title_sort Treatment compliance of patients with paracoccidioidomycosis in Central-West Brazil
author Andrade,Ursulla Vilella
author_facet Andrade,Ursulla Vilella
Oliveira,Sandra Maria do Valle Leone de
Chang,Marilene Rodrigues
Pereira,Edy Firmina
Marques,Ana Paula da Costa
Carvalho,Lidia Raquel de
Mendes,Rinaldo Poncio
Paniago,Anamaria Mello Miranda
author_role author
author2 Oliveira,Sandra Maria do Valle Leone de
Chang,Marilene Rodrigues
Pereira,Edy Firmina
Marques,Ana Paula da Costa
Carvalho,Lidia Raquel de
Mendes,Rinaldo Poncio
Paniago,Anamaria Mello Miranda
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Andrade,Ursulla Vilella
Oliveira,Sandra Maria do Valle Leone de
Chang,Marilene Rodrigues
Pereira,Edy Firmina
Marques,Ana Paula da Costa
Carvalho,Lidia Raquel de
Mendes,Rinaldo Poncio
Paniago,Anamaria Mello Miranda
dc.subject.por.fl_str_mv Paracoccidioidomycosis
Treatment adherence and compliance
loss to follow-up
mycoses
topic Paracoccidioidomycosis
Treatment adherence and compliance
loss to follow-up
mycoses
description ABSTRACT Objective: To evaluate the treatment compliance of patients with paracoccidioidomycosis. Methods: We studied 188 patients with paracoccidioidomycosis admitted to a tertiary referral hospital in the Central-West Region of Brazil from 2000 to 2010, to assess their compliance to treatment. In order to be considered compliant, patients needed to present two established criteria: (1) receive medicines from the pharmacy, and (2) achieve a self-reported utilization of at least 80% of the dispensed antifungal compounds prescribed since their previous appointment. Results: Most patients were male (95.7%), had the chronic form of the disease (94.2%), and were treated with cotrimoxazole (86.2%). Only 44.6% of patients were treatment compliant. The highest loss to follow-up was observed in the first 4 months of treatment (p < 0.02). Treatment compliance was higher for patients with than for those without pulmonary involvement (OR: 2.986; 95%CI 1.351-6.599), and higher for patients with than without tuberculosis as co-morbidity (OR: 2.763; 95%CI 1.004-7.604). Conclusions: Compliance to paracoccidioidomycosis treatment was low, and the period with the highest loss to follow-up corresponds to the first four months. Pulmonary paracoccidioidal involvement or tuberculosis comorbidity predicts a higher compliance to paracoccidioidomycosis therapy.
publishDate 2019
dc.date.none.fl_str_mv 2019-01-01
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dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/1806-3713/e20180167
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dc.publisher.none.fl_str_mv Sociedade Brasileira de Pneumologia e Tisiologia
publisher.none.fl_str_mv Sociedade Brasileira de Pneumologia e Tisiologia
dc.source.none.fl_str_mv Jornal Brasileiro de Pneumologia v.45 n.2 2019
reponame:Jornal Brasileiro de Pneumologia (Online)
instname:Sociedade Brasileira de Pneumologia e Tisiologia (SBPT)
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reponame_str Jornal Brasileiro de Pneumologia (Online)
collection Jornal Brasileiro de Pneumologia (Online)
repository.name.fl_str_mv Jornal Brasileiro de Pneumologia (Online) - Sociedade Brasileira de Pneumologia e Tisiologia (SBPT)
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