A new biphenyl from Clusia melchiorii and a new tocotrienol from C. obdeltifolia

• Autor(a) principal: Teixeira,Josanaide S. R.
• Data de Publicação: 2006
• Outros Autores: Moreira,Luciana de M., Guedes,Maria L. da S., Cruz,Frederico G.
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Journal of the Brazilian Chemical Society (Online)
• Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532006000400027
• topic: Clusia obdeltifolia; Clusia melchiorii; Clusiaceae; biphenyl; tocotrienol; triterpene; xyloidone

Chromatographic purification of the dichloromethane extract of Clusia melchiorii trunk leading to the isolation of a new biphenyl, 2,2-dimethyl-5-hydroxi-7-phenylchromene, along with the known compounds 2,2-dimethyl-5,10-dihydro-2H-benzo[g]chromene-5,10-dione (xyloidone), betulinic acid, friedelin, friedelinol, euphol, sitostenone, stigmastenone and a mixture of beta-sitosterol and stigmasterol. The hexane extract of Clusia obdeltifolia trunk yielded, after chromatographic fractionation, a new delta-tocotrienilic alcohol 2Z, 6E, 10E-13-(6-hydroxy-2,8-dimethyl-3,4-dihydro-2H,2-chromenyl)-2,6,10-trimethyl-2,6, 10-tridecatrien-1-ol, along with 2Z and 2E-delta-tocotrienoloic acids, betulinic acid, betulonic acid, betunilic aldehyde, glutinol, friedelin, sitostenone and a mixture of beta-sitosterol and stigmasterol. Their structures were determined from spectral data and comparison with data from previously reported compounds.