Chemical Constituents from Cultures of the Fungus Marasmiellus ramealis (Bull.) Singer

Detalhes bibliográficos
Autor(a) principal: Yang,Ningning
Data de Publicação: 2015
Outros Autores: Ma,Qingyun, Huang,Shengzhuo, Dai,Haofu, Guo,Zhikai, Lu,Xuehua, Wang,Yuguang, Yu,Zhifang, Zhao,Youxing
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Journal of the Brazilian Chemical Society (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532015000100009
Resumo: Chemical investigation on the cultures of the fungus Marasmiellus ramealis resulted in the first isolation of eleven compounds including two new eudesmane-type sesquiterpenoids 14(10→1)abeo-eudesmane-13-hydroxyl-11-ene, 14(10→1)abeo-eudesmane-11,13-diol, and the new mellein derivative (R)-(–)-5-ethoxycarbonyl mellein. The first two compounds were evaluated for their inhibitory activity against acetylcholinesterase (AChE), and proved to be active with a percentage inhibition of 29 and 41%, respectively, at a concentration of 100 μmol L-1.
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spelling Chemical Constituents from Cultures of the Fungus Marasmiellus ramealis (Bull.) SingerMarasmiellus ramealis (Bull.) SingereudesmanesesquiterpenoidsmelleinAChE inhibitionChemical investigation on the cultures of the fungus Marasmiellus ramealis resulted in the first isolation of eleven compounds including two new eudesmane-type sesquiterpenoids 14(10→1)abeo-eudesmane-13-hydroxyl-11-ene, 14(10→1)abeo-eudesmane-11,13-diol, and the new mellein derivative (R)-(–)-5-ethoxycarbonyl mellein. The first two compounds were evaluated for their inhibitory activity against acetylcholinesterase (AChE), and proved to be active with a percentage inhibition of 29 and 41%, respectively, at a concentration of 100 μmol L-1.Sociedade Brasileira de Química2015-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532015000100009Journal of the Brazilian Chemical Society v.26 n.1 2015reponame:Journal of the Brazilian Chemical Society (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.5935/0103-5053.20140206info:eu-repo/semantics/openAccessYang,NingningMa,QingyunHuang,ShengzhuoDai,HaofuGuo,ZhikaiLu,XuehuaWang,YuguangYu,ZhifangZhao,Youxingeng2015-02-03T00:00:00Zoai:scielo:S0103-50532015000100009Revistahttp://jbcs.sbq.org.brONGhttps://old.scielo.br/oai/scielo-oai.php||office@jbcs.sbq.org.br1678-47900103-5053opendoar:2015-02-03T00:00Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ)false
dc.title.none.fl_str_mv Chemical Constituents from Cultures of the Fungus Marasmiellus ramealis (Bull.) Singer
title Chemical Constituents from Cultures of the Fungus Marasmiellus ramealis (Bull.) Singer
spellingShingle Chemical Constituents from Cultures of the Fungus Marasmiellus ramealis (Bull.) Singer
Yang,Ningning
Marasmiellus ramealis (Bull.) Singer
eudesmane
sesquiterpenoids
mellein
AChE inhibition
title_short Chemical Constituents from Cultures of the Fungus Marasmiellus ramealis (Bull.) Singer
title_full Chemical Constituents from Cultures of the Fungus Marasmiellus ramealis (Bull.) Singer
title_fullStr Chemical Constituents from Cultures of the Fungus Marasmiellus ramealis (Bull.) Singer
title_full_unstemmed Chemical Constituents from Cultures of the Fungus Marasmiellus ramealis (Bull.) Singer
title_sort Chemical Constituents from Cultures of the Fungus Marasmiellus ramealis (Bull.) Singer
author Yang,Ningning
author_facet Yang,Ningning
Ma,Qingyun
Huang,Shengzhuo
Dai,Haofu
Guo,Zhikai
Lu,Xuehua
Wang,Yuguang
Yu,Zhifang
Zhao,Youxing
author_role author
author2 Ma,Qingyun
Huang,Shengzhuo
Dai,Haofu
Guo,Zhikai
Lu,Xuehua
Wang,Yuguang
Yu,Zhifang
Zhao,Youxing
author2_role author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Yang,Ningning
Ma,Qingyun
Huang,Shengzhuo
Dai,Haofu
Guo,Zhikai
Lu,Xuehua
Wang,Yuguang
Yu,Zhifang
Zhao,Youxing
dc.subject.por.fl_str_mv Marasmiellus ramealis (Bull.) Singer
eudesmane
sesquiterpenoids
mellein
AChE inhibition
topic Marasmiellus ramealis (Bull.) Singer
eudesmane
sesquiterpenoids
mellein
AChE inhibition
description Chemical investigation on the cultures of the fungus Marasmiellus ramealis resulted in the first isolation of eleven compounds including two new eudesmane-type sesquiterpenoids 14(10→1)abeo-eudesmane-13-hydroxyl-11-ene, 14(10→1)abeo-eudesmane-11,13-diol, and the new mellein derivative (R)-(–)-5-ethoxycarbonyl mellein. The first two compounds were evaluated for their inhibitory activity against acetylcholinesterase (AChE), and proved to be active with a percentage inhibition of 29 and 41%, respectively, at a concentration of 100 μmol L-1.
publishDate 2015
dc.date.none.fl_str_mv 2015-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532015000100009
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532015000100009
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.5935/0103-5053.20140206
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Química
publisher.none.fl_str_mv Sociedade Brasileira de Química
dc.source.none.fl_str_mv Journal of the Brazilian Chemical Society v.26 n.1 2015
reponame:Journal of the Brazilian Chemical Society (Online)
instname:Sociedade Brasileira de Química (SBQ)
instacron:SBQ
instname_str Sociedade Brasileira de Química (SBQ)
instacron_str SBQ
institution SBQ
reponame_str Journal of the Brazilian Chemical Society (Online)
collection Journal of the Brazilian Chemical Society (Online)
repository.name.fl_str_mv Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ)
repository.mail.fl_str_mv ||office@jbcs.sbq.org.br
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