Pyrrolizidine alkaloids from Heliotropium indicum

Detalhes bibliográficos
Autor(a) principal: Souza,João Sammy N.
Data de Publicação: 2005
Outros Autores: Machado,Luciana L., Pessoa,Otília D. L., Braz-Filho,Raimundo, Overk,Cassia R., Yao,Ping, Cordell,Geoffrey A., Lemos,Telma L. G.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Journal of the Brazilian Chemical Society (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532005000800019
Resumo: Helindicine (1), a new pyrrolizidine alkaloid with unusual structural features, together with the known lycopsamine (2), were isolated from the roots of Heliotropium indicum (Boraginaceae). The structures were established by a combination of 1D and 2D NMR methods (COSY, HMQC, HMBC, and NOESY) and HREIMS. This is the first report of a lactone pyrrolizidine alkaloid in the genus Heliotropium. Compounds 1 and 2 were assayed for antioxidant activity and showed moderate activity.
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spelling Pyrrolizidine alkaloids from Heliotropium indicumHeliotropium indicumBoraginaceaepyrrolizidine alkaloidsantioxidant activityHelindicine (1), a new pyrrolizidine alkaloid with unusual structural features, together with the known lycopsamine (2), were isolated from the roots of Heliotropium indicum (Boraginaceae). The structures were established by a combination of 1D and 2D NMR methods (COSY, HMQC, HMBC, and NOESY) and HREIMS. This is the first report of a lactone pyrrolizidine alkaloid in the genus Heliotropium. Compounds 1 and 2 were assayed for antioxidant activity and showed moderate activity.Sociedade Brasileira de Química2005-11-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532005000800019Journal of the Brazilian Chemical Society v.16 n.6b 2005reponame:Journal of the Brazilian Chemical Society (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.1590/S0103-50532005000800019info:eu-repo/semantics/openAccessSouza,João Sammy N.Machado,Luciana L.Pessoa,Otília D. L.Braz-Filho,RaimundoOverk,Cassia R.Yao,PingCordell,Geoffrey A.Lemos,Telma L. G.eng2006-01-20T00:00:00Zoai:scielo:S0103-50532005000800019Revistahttp://jbcs.sbq.org.brONGhttps://old.scielo.br/oai/scielo-oai.php||office@jbcs.sbq.org.br1678-47900103-5053opendoar:2006-01-20T00:00Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ)false
dc.title.none.fl_str_mv Pyrrolizidine alkaloids from Heliotropium indicum
title Pyrrolizidine alkaloids from Heliotropium indicum
spellingShingle Pyrrolizidine alkaloids from Heliotropium indicum
Souza,João Sammy N.
Heliotropium indicum
Boraginaceae
pyrrolizidine alkaloids
antioxidant activity
title_short Pyrrolizidine alkaloids from Heliotropium indicum
title_full Pyrrolizidine alkaloids from Heliotropium indicum
title_fullStr Pyrrolizidine alkaloids from Heliotropium indicum
title_full_unstemmed Pyrrolizidine alkaloids from Heliotropium indicum
title_sort Pyrrolizidine alkaloids from Heliotropium indicum
author Souza,João Sammy N.
author_facet Souza,João Sammy N.
Machado,Luciana L.
Pessoa,Otília D. L.
Braz-Filho,Raimundo
Overk,Cassia R.
Yao,Ping
Cordell,Geoffrey A.
Lemos,Telma L. G.
author_role author
author2 Machado,Luciana L.
Pessoa,Otília D. L.
Braz-Filho,Raimundo
Overk,Cassia R.
Yao,Ping
Cordell,Geoffrey A.
Lemos,Telma L. G.
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Souza,João Sammy N.
Machado,Luciana L.
Pessoa,Otília D. L.
Braz-Filho,Raimundo
Overk,Cassia R.
Yao,Ping
Cordell,Geoffrey A.
Lemos,Telma L. G.
dc.subject.por.fl_str_mv Heliotropium indicum
Boraginaceae
pyrrolizidine alkaloids
antioxidant activity
topic Heliotropium indicum
Boraginaceae
pyrrolizidine alkaloids
antioxidant activity
description Helindicine (1), a new pyrrolizidine alkaloid with unusual structural features, together with the known lycopsamine (2), were isolated from the roots of Heliotropium indicum (Boraginaceae). The structures were established by a combination of 1D and 2D NMR methods (COSY, HMQC, HMBC, and NOESY) and HREIMS. This is the first report of a lactone pyrrolizidine alkaloid in the genus Heliotropium. Compounds 1 and 2 were assayed for antioxidant activity and showed moderate activity.
publishDate 2005
dc.date.none.fl_str_mv 2005-11-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532005000800019
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532005000800019
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0103-50532005000800019
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Química
publisher.none.fl_str_mv Sociedade Brasileira de Química
dc.source.none.fl_str_mv Journal of the Brazilian Chemical Society v.16 n.6b 2005
reponame:Journal of the Brazilian Chemical Society (Online)
instname:Sociedade Brasileira de Química (SBQ)
instacron:SBQ
instname_str Sociedade Brasileira de Química (SBQ)
instacron_str SBQ
institution SBQ
reponame_str Journal of the Brazilian Chemical Society (Online)
collection Journal of the Brazilian Chemical Society (Online)
repository.name.fl_str_mv Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ)
repository.mail.fl_str_mv ||office@jbcs.sbq.org.br
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