Single-Layered Paper-Based Microfluidic Devices Made by Paint-Spraying Technique with Great Barrier Resistance for Colorimetric Assays
Autor(a) principal: | |
---|---|
Data de Publicação: | 2021 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Journal of the Brazilian Chemical Society (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532021000300599 |
Resumo: | The single-layered paint-spraying paper based microfluidic devices (sp-μPADs) have been for the first time integrated with the colorimetric assay. The polymethyl methacrylate (PMMA) board was applied as the mask instead of the iron mask, reducing the power requirement of the cutting machine. The paint was sprayed into the paper, which blocked the pores of the paper and constructed the hydrophobic barrier on the paper. The paint barrier was highly resistant to the various kind of chemicals and the minimum channel dimensions was 1.4 mm. By using the PMMA masks with different designs, the sp-μPADs with different designs have been fabricated and successfully applied to the single analyte assay of iron or bovine serum albumin (BSA) and the simultaneous assay of copper and nickel. Moreover, the feasibility of the multiplexed assay of eight analytes was also demonstrated. The analytical performances indicated that the fabricated sp-μPADs offered a promising platform in the colorimetric assays of either single or multiple analytes. |
id |
SBQ-2_515bdde96bdd8913f9828f9fd0f27f6f |
---|---|
oai_identifier_str |
oai:scielo:S0103-50532021000300599 |
network_acronym_str |
SBQ-2 |
network_name_str |
Journal of the Brazilian Chemical Society (Online) |
repository_id_str |
|
spelling |
Single-Layered Paper-Based Microfluidic Devices Made by Paint-Spraying Technique with Great Barrier Resistance for Colorimetric Assaysmicrofluidicspaper-based devicespaint sprayingcolorimetryThe single-layered paint-spraying paper based microfluidic devices (sp-μPADs) have been for the first time integrated with the colorimetric assay. The polymethyl methacrylate (PMMA) board was applied as the mask instead of the iron mask, reducing the power requirement of the cutting machine. The paint was sprayed into the paper, which blocked the pores of the paper and constructed the hydrophobic barrier on the paper. The paint barrier was highly resistant to the various kind of chemicals and the minimum channel dimensions was 1.4 mm. By using the PMMA masks with different designs, the sp-μPADs with different designs have been fabricated and successfully applied to the single analyte assay of iron or bovine serum albumin (BSA) and the simultaneous assay of copper and nickel. Moreover, the feasibility of the multiplexed assay of eight analytes was also demonstrated. The analytical performances indicated that the fabricated sp-μPADs offered a promising platform in the colorimetric assays of either single or multiple analytes.Sociedade Brasileira de Química2021-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532021000300599Journal of the Brazilian Chemical Society v.32 n.3 2021reponame:Journal of the Brazilian Chemical Society (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.21577/0103-5053.20200213info:eu-repo/semantics/openAccessNie,BeixiZhao,ShaoyuDeng,MuhanYu,PengYang,YiLei,WeixinYin,Lueng2021-02-25T00:00:00Zoai:scielo:S0103-50532021000300599Revistahttp://jbcs.sbq.org.brONGhttps://old.scielo.br/oai/scielo-oai.php||office@jbcs.sbq.org.br1678-47900103-5053opendoar:2021-02-25T00:00Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ)false |
dc.title.none.fl_str_mv |
Single-Layered Paper-Based Microfluidic Devices Made by Paint-Spraying Technique with Great Barrier Resistance for Colorimetric Assays |
title |
Single-Layered Paper-Based Microfluidic Devices Made by Paint-Spraying Technique with Great Barrier Resistance for Colorimetric Assays |
spellingShingle |
Single-Layered Paper-Based Microfluidic Devices Made by Paint-Spraying Technique with Great Barrier Resistance for Colorimetric Assays Nie,Beixi microfluidics paper-based devices paint spraying colorimetry |
title_short |
Single-Layered Paper-Based Microfluidic Devices Made by Paint-Spraying Technique with Great Barrier Resistance for Colorimetric Assays |
title_full |
Single-Layered Paper-Based Microfluidic Devices Made by Paint-Spraying Technique with Great Barrier Resistance for Colorimetric Assays |
title_fullStr |
Single-Layered Paper-Based Microfluidic Devices Made by Paint-Spraying Technique with Great Barrier Resistance for Colorimetric Assays |
title_full_unstemmed |
Single-Layered Paper-Based Microfluidic Devices Made by Paint-Spraying Technique with Great Barrier Resistance for Colorimetric Assays |
title_sort |
Single-Layered Paper-Based Microfluidic Devices Made by Paint-Spraying Technique with Great Barrier Resistance for Colorimetric Assays |
author |
Nie,Beixi |
author_facet |
Nie,Beixi Zhao,Shaoyu Deng,Muhan Yu,Peng Yang,Yi Lei,Weixin Yin,Lu |
author_role |
author |
author2 |
Zhao,Shaoyu Deng,Muhan Yu,Peng Yang,Yi Lei,Weixin Yin,Lu |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Nie,Beixi Zhao,Shaoyu Deng,Muhan Yu,Peng Yang,Yi Lei,Weixin Yin,Lu |
dc.subject.por.fl_str_mv |
microfluidics paper-based devices paint spraying colorimetry |
topic |
microfluidics paper-based devices paint spraying colorimetry |
description |
The single-layered paint-spraying paper based microfluidic devices (sp-μPADs) have been for the first time integrated with the colorimetric assay. The polymethyl methacrylate (PMMA) board was applied as the mask instead of the iron mask, reducing the power requirement of the cutting machine. The paint was sprayed into the paper, which blocked the pores of the paper and constructed the hydrophobic barrier on the paper. The paint barrier was highly resistant to the various kind of chemicals and the minimum channel dimensions was 1.4 mm. By using the PMMA masks with different designs, the sp-μPADs with different designs have been fabricated and successfully applied to the single analyte assay of iron or bovine serum albumin (BSA) and the simultaneous assay of copper and nickel. Moreover, the feasibility of the multiplexed assay of eight analytes was also demonstrated. The analytical performances indicated that the fabricated sp-μPADs offered a promising platform in the colorimetric assays of either single or multiple analytes. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-03-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532021000300599 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532021000300599 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.21577/0103-5053.20200213 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Química |
publisher.none.fl_str_mv |
Sociedade Brasileira de Química |
dc.source.none.fl_str_mv |
Journal of the Brazilian Chemical Society v.32 n.3 2021 reponame:Journal of the Brazilian Chemical Society (Online) instname:Sociedade Brasileira de Química (SBQ) instacron:SBQ |
instname_str |
Sociedade Brasileira de Química (SBQ) |
instacron_str |
SBQ |
institution |
SBQ |
reponame_str |
Journal of the Brazilian Chemical Society (Online) |
collection |
Journal of the Brazilian Chemical Society (Online) |
repository.name.fl_str_mv |
Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ) |
repository.mail.fl_str_mv |
||office@jbcs.sbq.org.br |
_version_ |
1750318183958446080 |