Single-Layered Paper-Based Microfluidic Devices Made by Paint-Spraying Technique with Great Barrier Resistance for Colorimetric Assays

Detalhes bibliográficos
Autor(a) principal: Nie,Beixi
Data de Publicação: 2021
Outros Autores: Zhao,Shaoyu, Deng,Muhan, Yu,Peng, Yang,Yi, Lei,Weixin, Yin,Lu
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Journal of the Brazilian Chemical Society (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532021000300599
Resumo: The single-layered paint-spraying paper based microfluidic devices (sp-μPADs) have been for the first time integrated with the colorimetric assay. The polymethyl methacrylate (PMMA) board was applied as the mask instead of the iron mask, reducing the power requirement of the cutting machine. The paint was sprayed into the paper, which blocked the pores of the paper and constructed the hydrophobic barrier on the paper. The paint barrier was highly resistant to the various kind of chemicals and the minimum channel dimensions was 1.4 mm. By using the PMMA masks with different designs, the sp-μPADs with different designs have been fabricated and successfully applied to the single analyte assay of iron or bovine serum albumin (BSA) and the simultaneous assay of copper and nickel. Moreover, the feasibility of the multiplexed assay of eight analytes was also demonstrated. The analytical performances indicated that the fabricated sp-μPADs offered a promising platform in the colorimetric assays of either single or multiple analytes.
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spelling Single-Layered Paper-Based Microfluidic Devices Made by Paint-Spraying Technique with Great Barrier Resistance for Colorimetric Assaysmicrofluidicspaper-based devicespaint sprayingcolorimetryThe single-layered paint-spraying paper based microfluidic devices (sp-μPADs) have been for the first time integrated with the colorimetric assay. The polymethyl methacrylate (PMMA) board was applied as the mask instead of the iron mask, reducing the power requirement of the cutting machine. The paint was sprayed into the paper, which blocked the pores of the paper and constructed the hydrophobic barrier on the paper. The paint barrier was highly resistant to the various kind of chemicals and the minimum channel dimensions was 1.4 mm. By using the PMMA masks with different designs, the sp-μPADs with different designs have been fabricated and successfully applied to the single analyte assay of iron or bovine serum albumin (BSA) and the simultaneous assay of copper and nickel. Moreover, the feasibility of the multiplexed assay of eight analytes was also demonstrated. The analytical performances indicated that the fabricated sp-μPADs offered a promising platform in the colorimetric assays of either single or multiple analytes.Sociedade Brasileira de Química2021-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532021000300599Journal of the Brazilian Chemical Society v.32 n.3 2021reponame:Journal of the Brazilian Chemical Society (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.21577/0103-5053.20200213info:eu-repo/semantics/openAccessNie,BeixiZhao,ShaoyuDeng,MuhanYu,PengYang,YiLei,WeixinYin,Lueng2021-02-25T00:00:00Zoai:scielo:S0103-50532021000300599Revistahttp://jbcs.sbq.org.brONGhttps://old.scielo.br/oai/scielo-oai.php||office@jbcs.sbq.org.br1678-47900103-5053opendoar:2021-02-25T00:00Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ)false
dc.title.none.fl_str_mv Single-Layered Paper-Based Microfluidic Devices Made by Paint-Spraying Technique with Great Barrier Resistance for Colorimetric Assays
title Single-Layered Paper-Based Microfluidic Devices Made by Paint-Spraying Technique with Great Barrier Resistance for Colorimetric Assays
spellingShingle Single-Layered Paper-Based Microfluidic Devices Made by Paint-Spraying Technique with Great Barrier Resistance for Colorimetric Assays
Nie,Beixi
microfluidics
paper-based devices
paint spraying
colorimetry
title_short Single-Layered Paper-Based Microfluidic Devices Made by Paint-Spraying Technique with Great Barrier Resistance for Colorimetric Assays
title_full Single-Layered Paper-Based Microfluidic Devices Made by Paint-Spraying Technique with Great Barrier Resistance for Colorimetric Assays
title_fullStr Single-Layered Paper-Based Microfluidic Devices Made by Paint-Spraying Technique with Great Barrier Resistance for Colorimetric Assays
title_full_unstemmed Single-Layered Paper-Based Microfluidic Devices Made by Paint-Spraying Technique with Great Barrier Resistance for Colorimetric Assays
title_sort Single-Layered Paper-Based Microfluidic Devices Made by Paint-Spraying Technique with Great Barrier Resistance for Colorimetric Assays
author Nie,Beixi
author_facet Nie,Beixi
Zhao,Shaoyu
Deng,Muhan
Yu,Peng
Yang,Yi
Lei,Weixin
Yin,Lu
author_role author
author2 Zhao,Shaoyu
Deng,Muhan
Yu,Peng
Yang,Yi
Lei,Weixin
Yin,Lu
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Nie,Beixi
Zhao,Shaoyu
Deng,Muhan
Yu,Peng
Yang,Yi
Lei,Weixin
Yin,Lu
dc.subject.por.fl_str_mv microfluidics
paper-based devices
paint spraying
colorimetry
topic microfluidics
paper-based devices
paint spraying
colorimetry
description The single-layered paint-spraying paper based microfluidic devices (sp-μPADs) have been for the first time integrated with the colorimetric assay. The polymethyl methacrylate (PMMA) board was applied as the mask instead of the iron mask, reducing the power requirement of the cutting machine. The paint was sprayed into the paper, which blocked the pores of the paper and constructed the hydrophobic barrier on the paper. The paint barrier was highly resistant to the various kind of chemicals and the minimum channel dimensions was 1.4 mm. By using the PMMA masks with different designs, the sp-μPADs with different designs have been fabricated and successfully applied to the single analyte assay of iron or bovine serum albumin (BSA) and the simultaneous assay of copper and nickel. Moreover, the feasibility of the multiplexed assay of eight analytes was also demonstrated. The analytical performances indicated that the fabricated sp-μPADs offered a promising platform in the colorimetric assays of either single or multiple analytes.
publishDate 2021
dc.date.none.fl_str_mv 2021-03-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532021000300599
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532021000300599
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.21577/0103-5053.20200213
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Química
publisher.none.fl_str_mv Sociedade Brasileira de Química
dc.source.none.fl_str_mv Journal of the Brazilian Chemical Society v.32 n.3 2021
reponame:Journal of the Brazilian Chemical Society (Online)
instname:Sociedade Brasileira de Química (SBQ)
instacron:SBQ
instname_str Sociedade Brasileira de Química (SBQ)
instacron_str SBQ
institution SBQ
reponame_str Journal of the Brazilian Chemical Society (Online)
collection Journal of the Brazilian Chemical Society (Online)
repository.name.fl_str_mv Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ)
repository.mail.fl_str_mv ||office@jbcs.sbq.org.br
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