Glycyrrhizin and glycyrrhetic acid: scaffolds to promising new pharmacologically active compounds

Detalhes bibliográficos
Autor(a) principal: Graebin,Cedric S
Data de Publicação: 2010
Outros Autores: Verli,Hugo, Guimarães,Jorge A
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Journal of the Brazilian Chemical Society (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532010000900002
Resumo: Glycyrrhizinic acid (GL), also known as glycyrrhizin, is a triterpene saponin, a natural product found on the root of Glycyrrhyza glabra L. ("licquorice"), used worldwide as sweetener and in the traditional eastern medicines. This review is focused on a series of new derivatives synthesized using GL and its aglycon, glycyrrhetinic acid (GLA), as starting materials, the pharmacological activities described for those compounds, as well as new activities reported for GL and GLA themselves.
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spelling Glycyrrhizin and glycyrrhetic acid: scaffolds to promising new pharmacologically active compoundsglycyrrhizinglycyrrhetic acidglycyrrhetinic acidlicquoriceorganic synthesispharmacological activityGlycyrrhizinic acid (GL), also known as glycyrrhizin, is a triterpene saponin, a natural product found on the root of Glycyrrhyza glabra L. ("licquorice"), used worldwide as sweetener and in the traditional eastern medicines. This review is focused on a series of new derivatives synthesized using GL and its aglycon, glycyrrhetinic acid (GLA), as starting materials, the pharmacological activities described for those compounds, as well as new activities reported for GL and GLA themselves.Sociedade Brasileira de Química2010-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532010000900002Journal of the Brazilian Chemical Society v.21 n.9 2010reponame:Journal of the Brazilian Chemical Society (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.1590/S0103-50532010000900002info:eu-repo/semantics/openAccessGraebin,Cedric SVerli,HugoGuimarães,Jorge Aeng2010-09-10T00:00:00Zoai:scielo:S0103-50532010000900002Revistahttp://jbcs.sbq.org.brONGhttps://old.scielo.br/oai/scielo-oai.php||office@jbcs.sbq.org.br1678-47900103-5053opendoar:2010-09-10T00:00Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ)false
dc.title.none.fl_str_mv Glycyrrhizin and glycyrrhetic acid: scaffolds to promising new pharmacologically active compounds
title Glycyrrhizin and glycyrrhetic acid: scaffolds to promising new pharmacologically active compounds
spellingShingle Glycyrrhizin and glycyrrhetic acid: scaffolds to promising new pharmacologically active compounds
Graebin,Cedric S
glycyrrhizin
glycyrrhetic acid
glycyrrhetinic acid
licquorice
organic synthesis
pharmacological activity
title_short Glycyrrhizin and glycyrrhetic acid: scaffolds to promising new pharmacologically active compounds
title_full Glycyrrhizin and glycyrrhetic acid: scaffolds to promising new pharmacologically active compounds
title_fullStr Glycyrrhizin and glycyrrhetic acid: scaffolds to promising new pharmacologically active compounds
title_full_unstemmed Glycyrrhizin and glycyrrhetic acid: scaffolds to promising new pharmacologically active compounds
title_sort Glycyrrhizin and glycyrrhetic acid: scaffolds to promising new pharmacologically active compounds
author Graebin,Cedric S
author_facet Graebin,Cedric S
Verli,Hugo
Guimarães,Jorge A
author_role author
author2 Verli,Hugo
Guimarães,Jorge A
author2_role author
author
dc.contributor.author.fl_str_mv Graebin,Cedric S
Verli,Hugo
Guimarães,Jorge A
dc.subject.por.fl_str_mv glycyrrhizin
glycyrrhetic acid
glycyrrhetinic acid
licquorice
organic synthesis
pharmacological activity
topic glycyrrhizin
glycyrrhetic acid
glycyrrhetinic acid
licquorice
organic synthesis
pharmacological activity
description Glycyrrhizinic acid (GL), also known as glycyrrhizin, is a triterpene saponin, a natural product found on the root of Glycyrrhyza glabra L. ("licquorice"), used worldwide as sweetener and in the traditional eastern medicines. This review is focused on a series of new derivatives synthesized using GL and its aglycon, glycyrrhetinic acid (GLA), as starting materials, the pharmacological activities described for those compounds, as well as new activities reported for GL and GLA themselves.
publishDate 2010
dc.date.none.fl_str_mv 2010-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532010000900002
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532010000900002
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0103-50532010000900002
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Química
publisher.none.fl_str_mv Sociedade Brasileira de Química
dc.source.none.fl_str_mv Journal of the Brazilian Chemical Society v.21 n.9 2010
reponame:Journal of the Brazilian Chemical Society (Online)
instname:Sociedade Brasileira de Química (SBQ)
instacron:SBQ
instname_str Sociedade Brasileira de Química (SBQ)
instacron_str SBQ
institution SBQ
reponame_str Journal of the Brazilian Chemical Society (Online)
collection Journal of the Brazilian Chemical Society (Online)
repository.name.fl_str_mv Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ)
repository.mail.fl_str_mv ||office@jbcs.sbq.org.br
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