A green, inexpensive and efficient organocatalyzed procedure for aqueous aldol condensations

Detalhes bibliográficos
Autor(a) principal: Abaee,M. Saeed
Data de Publicação: 2009
Outros Autores: Mojtahedi,Mohammad M., Forghani,Soudabeh, Ghandchi,Nafiseh M., Forouzani,Mehdi, Sharifi,Roholah, Chaharnazm,Behnam
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Journal of the Brazilian Chemical Society (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532009001000018
Resumo: A facile and general procedure is presented for diethylamine-catalyzed double crossed aldol condensation of cyclic ketones with various aromatic aldehydes under aqueous conditions. Excellent yields of 3,5-bisarylmethylidenes of homocyclic and heterocyclic ketones are achieved in a one-pot procedure. Furthermore, the methodology is efficiently applied to the synthesis of chalcones from their corresponding methyl ketones. In the majority of the cases studied, products precipitate from the reaction mixtures and the medium is recycled in subsequent several reactions without significant loss of activity.
id SBQ-2_54e2c9cbf5da2d936546b2869c505818
oai_identifier_str oai:scielo:S0103-50532009001000018
network_acronym_str SBQ-2
network_name_str Journal of the Brazilian Chemical Society (Online)
repository_id_str
spelling A green, inexpensive and efficient organocatalyzed procedure for aqueous aldol condensationsaldol condensationaqueous conditionsorganocatalystbisarylmethylideneschalconesA facile and general procedure is presented for diethylamine-catalyzed double crossed aldol condensation of cyclic ketones with various aromatic aldehydes under aqueous conditions. Excellent yields of 3,5-bisarylmethylidenes of homocyclic and heterocyclic ketones are achieved in a one-pot procedure. Furthermore, the methodology is efficiently applied to the synthesis of chalcones from their corresponding methyl ketones. In the majority of the cases studied, products precipitate from the reaction mixtures and the medium is recycled in subsequent several reactions without significant loss of activity.Sociedade Brasileira de Química2009-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532009001000018Journal of the Brazilian Chemical Society v.20 n.10 2009reponame:Journal of the Brazilian Chemical Society (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.1590/S0103-50532009001000018info:eu-repo/semantics/openAccessAbaee,M. SaeedMojtahedi,Mohammad M.Forghani,SoudabehGhandchi,Nafiseh M.Forouzani,MehdiSharifi,RoholahChaharnazm,Behnameng2011-10-14T00:00:00Zoai:scielo:S0103-50532009001000018Revistahttp://jbcs.sbq.org.brONGhttps://old.scielo.br/oai/scielo-oai.php||office@jbcs.sbq.org.br1678-47900103-5053opendoar:2011-10-14T00:00Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ)false
dc.title.none.fl_str_mv A green, inexpensive and efficient organocatalyzed procedure for aqueous aldol condensations
title A green, inexpensive and efficient organocatalyzed procedure for aqueous aldol condensations
spellingShingle A green, inexpensive and efficient organocatalyzed procedure for aqueous aldol condensations
Abaee,M. Saeed
aldol condensation
aqueous conditions
organocatalyst
bisarylmethylidenes
chalcones
title_short A green, inexpensive and efficient organocatalyzed procedure for aqueous aldol condensations
title_full A green, inexpensive and efficient organocatalyzed procedure for aqueous aldol condensations
title_fullStr A green, inexpensive and efficient organocatalyzed procedure for aqueous aldol condensations
title_full_unstemmed A green, inexpensive and efficient organocatalyzed procedure for aqueous aldol condensations
title_sort A green, inexpensive and efficient organocatalyzed procedure for aqueous aldol condensations
author Abaee,M. Saeed
author_facet Abaee,M. Saeed
Mojtahedi,Mohammad M.
Forghani,Soudabeh
Ghandchi,Nafiseh M.
Forouzani,Mehdi
Sharifi,Roholah
Chaharnazm,Behnam
author_role author
author2 Mojtahedi,Mohammad M.
Forghani,Soudabeh
Ghandchi,Nafiseh M.
Forouzani,Mehdi
Sharifi,Roholah
Chaharnazm,Behnam
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Abaee,M. Saeed
Mojtahedi,Mohammad M.
Forghani,Soudabeh
Ghandchi,Nafiseh M.
Forouzani,Mehdi
Sharifi,Roholah
Chaharnazm,Behnam
dc.subject.por.fl_str_mv aldol condensation
aqueous conditions
organocatalyst
bisarylmethylidenes
chalcones
topic aldol condensation
aqueous conditions
organocatalyst
bisarylmethylidenes
chalcones
description A facile and general procedure is presented for diethylamine-catalyzed double crossed aldol condensation of cyclic ketones with various aromatic aldehydes under aqueous conditions. Excellent yields of 3,5-bisarylmethylidenes of homocyclic and heterocyclic ketones are achieved in a one-pot procedure. Furthermore, the methodology is efficiently applied to the synthesis of chalcones from their corresponding methyl ketones. In the majority of the cases studied, products precipitate from the reaction mixtures and the medium is recycled in subsequent several reactions without significant loss of activity.
publishDate 2009
dc.date.none.fl_str_mv 2009-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532009001000018
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532009001000018
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0103-50532009001000018
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Química
publisher.none.fl_str_mv Sociedade Brasileira de Química
dc.source.none.fl_str_mv Journal of the Brazilian Chemical Society v.20 n.10 2009
reponame:Journal of the Brazilian Chemical Society (Online)
instname:Sociedade Brasileira de Química (SBQ)
instacron:SBQ
instname_str Sociedade Brasileira de Química (SBQ)
instacron_str SBQ
institution SBQ
reponame_str Journal of the Brazilian Chemical Society (Online)
collection Journal of the Brazilian Chemical Society (Online)
repository.name.fl_str_mv Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ)
repository.mail.fl_str_mv ||office@jbcs.sbq.org.br
_version_ 1750318170311229440

Registros relacionados