Organotin(IV) complexes with 2-acetylpyridine benzoyl hydrazones: antimicrobial activity

Detalhes bibliográficos
Autor(a) principal: Despaigne,Angel A. R.
Data de Publicação: 2010
Outros Autores: Vieira,Lorena F., Mendes,Isolda C., Costa,Fernanda B. da, Speziali,Nivaldo L., Beraldo,Heloisa
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Journal of the Brazilian Chemical Society (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532010000700012
Resumo: Reaction of n-butyltin trichloride, [Bu nSnCl3], and phenyltin trichloride, [PhSnCl3], with 2-acetylpyridine benzoyl hydrazone (H2AcPh), 2-acetylpyridine para-chloro-benzoyl hydrazone (H2AcpClPh) and 2-acetylpyridine para-nitro-benzoyl hydrazone (H2AcpNO2Ph) gave [Bu nSn(2AcPh)Cl2] (1), [Bu nSn(2AcpClPh)Cl2] (2), [Bu nSn(2AcpNO2Ph)Cl2] (3), [PhSn(2AcPh)Cl2] (4), [PhSn(2AcpClPh)Cl2] (5) and [PhSn(2AcpNO2Ph)Cl2] (6) as products. Among the hydrazones H2AcpClPh proved to be the most active against Staphylococcus aureus and Candida albicans. Upon coordination the antibacterial activity of both tin and the hydrazones significantly increases. Complexes 2 and 5 revealed to be the most active as antimicrobial agents.
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spelling Organotin(IV) complexes with 2-acetylpyridine benzoyl hydrazones: antimicrobial activity2-acetylpyridine benzoyl hydrazonesorganotin(IV) complexescrystal structuresantimicrobial activityReaction of n-butyltin trichloride, [Bu nSnCl3], and phenyltin trichloride, [PhSnCl3], with 2-acetylpyridine benzoyl hydrazone (H2AcPh), 2-acetylpyridine para-chloro-benzoyl hydrazone (H2AcpClPh) and 2-acetylpyridine para-nitro-benzoyl hydrazone (H2AcpNO2Ph) gave [Bu nSn(2AcPh)Cl2] (1), [Bu nSn(2AcpClPh)Cl2] (2), [Bu nSn(2AcpNO2Ph)Cl2] (3), [PhSn(2AcPh)Cl2] (4), [PhSn(2AcpClPh)Cl2] (5) and [PhSn(2AcpNO2Ph)Cl2] (6) as products. Among the hydrazones H2AcpClPh proved to be the most active against Staphylococcus aureus and Candida albicans. Upon coordination the antibacterial activity of both tin and the hydrazones significantly increases. Complexes 2 and 5 revealed to be the most active as antimicrobial agents.Sociedade Brasileira de Química2010-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532010000700012Journal of the Brazilian Chemical Society v.21 n.7 2010reponame:Journal of the Brazilian Chemical Society (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.1590/S0103-50532010000700012info:eu-repo/semantics/openAccessDespaigne,Angel A. R.Vieira,Lorena F.Mendes,Isolda C.Costa,Fernanda B. daSpeziali,Nivaldo L.Beraldo,Heloisaeng2010-07-30T00:00:00Zoai:scielo:S0103-50532010000700012Revistahttp://jbcs.sbq.org.brONGhttps://old.scielo.br/oai/scielo-oai.php||office@jbcs.sbq.org.br1678-47900103-5053opendoar:2010-07-30T00:00Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ)false
dc.title.none.fl_str_mv Organotin(IV) complexes with 2-acetylpyridine benzoyl hydrazones: antimicrobial activity
title Organotin(IV) complexes with 2-acetylpyridine benzoyl hydrazones: antimicrobial activity
spellingShingle Organotin(IV) complexes with 2-acetylpyridine benzoyl hydrazones: antimicrobial activity
Despaigne,Angel A. R.
2-acetylpyridine benzoyl hydrazones
organotin(IV) complexes
crystal structures
antimicrobial activity
title_short Organotin(IV) complexes with 2-acetylpyridine benzoyl hydrazones: antimicrobial activity
title_full Organotin(IV) complexes with 2-acetylpyridine benzoyl hydrazones: antimicrobial activity
title_fullStr Organotin(IV) complexes with 2-acetylpyridine benzoyl hydrazones: antimicrobial activity
title_full_unstemmed Organotin(IV) complexes with 2-acetylpyridine benzoyl hydrazones: antimicrobial activity
title_sort Organotin(IV) complexes with 2-acetylpyridine benzoyl hydrazones: antimicrobial activity
author Despaigne,Angel A. R.
author_facet Despaigne,Angel A. R.
Vieira,Lorena F.
Mendes,Isolda C.
Costa,Fernanda B. da
Speziali,Nivaldo L.
Beraldo,Heloisa
author_role author
author2 Vieira,Lorena F.
Mendes,Isolda C.
Costa,Fernanda B. da
Speziali,Nivaldo L.
Beraldo,Heloisa
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Despaigne,Angel A. R.
Vieira,Lorena F.
Mendes,Isolda C.
Costa,Fernanda B. da
Speziali,Nivaldo L.
Beraldo,Heloisa
dc.subject.por.fl_str_mv 2-acetylpyridine benzoyl hydrazones
organotin(IV) complexes
crystal structures
antimicrobial activity
topic 2-acetylpyridine benzoyl hydrazones
organotin(IV) complexes
crystal structures
antimicrobial activity
description Reaction of n-butyltin trichloride, [Bu nSnCl3], and phenyltin trichloride, [PhSnCl3], with 2-acetylpyridine benzoyl hydrazone (H2AcPh), 2-acetylpyridine para-chloro-benzoyl hydrazone (H2AcpClPh) and 2-acetylpyridine para-nitro-benzoyl hydrazone (H2AcpNO2Ph) gave [Bu nSn(2AcPh)Cl2] (1), [Bu nSn(2AcpClPh)Cl2] (2), [Bu nSn(2AcpNO2Ph)Cl2] (3), [PhSn(2AcPh)Cl2] (4), [PhSn(2AcpClPh)Cl2] (5) and [PhSn(2AcpNO2Ph)Cl2] (6) as products. Among the hydrazones H2AcpClPh proved to be the most active against Staphylococcus aureus and Candida albicans. Upon coordination the antibacterial activity of both tin and the hydrazones significantly increases. Complexes 2 and 5 revealed to be the most active as antimicrobial agents.
publishDate 2010
dc.date.none.fl_str_mv 2010-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532010000700012
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532010000700012
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0103-50532010000700012
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Química
publisher.none.fl_str_mv Sociedade Brasileira de Química
dc.source.none.fl_str_mv Journal of the Brazilian Chemical Society v.21 n.7 2010
reponame:Journal of the Brazilian Chemical Society (Online)
instname:Sociedade Brasileira de Química (SBQ)
instacron:SBQ
instname_str Sociedade Brasileira de Química (SBQ)
instacron_str SBQ
institution SBQ
reponame_str Journal of the Brazilian Chemical Society (Online)
collection Journal of the Brazilian Chemical Society (Online)
repository.name.fl_str_mv Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ)
repository.mail.fl_str_mv ||office@jbcs.sbq.org.br
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