Compounds of Anthostomella brabeji, an Endophytic Fungus Isolated from Paepalanthus planifolius (Eriocaulaceae)
Autor(a) principal: | |
---|---|
Data de Publicação: | 2016 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Journal of the Brazilian Chemical Society (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532016000601048 |
Resumo: | In this study, fifteen endophytic fungi were isolated from Paepalanthus planifolius (Eriocaulaceae). From the capitula, seven endophytes were screened and evaluated for their metabolomic profile and radical scavenging activity (2,2-diphenyl-1-picrylhydrazyl (DPPH) assay). Chemical investigation of ethyl acetate extract of the endophytic fungus Anthostomella brabeji resulted in the isolation of one new compound, (+)-(6R*,7S*,8R*)-6,7,8-trihydroxy-2,2-dimethyl-5,6,7,8-tetrahydro-chroman-4-one, and three known compounds: 6-hydroxy-2,2-dimethyl-5,6,7,8-tetrahydro-7,8-epoxycroman-4-one, siccayne and eutypinol. All of the compound structures were elucidated using 1D and 2D nuclear magnetic resonance (NMR) and mass spectrometry (MS) analyses. The antimicrobial activity of the compounds and A. brabeji extract were assayed against the microorganisms Staphylococcus aureus, Escherichia coli, Salmonella setubal and Candida albicans. Measured minimal inhibitory concentration (MIC) values ranged from 31.25 to 1000.0 µg mL-1. |
id |
SBQ-2_82b0cbf4daa98ac6bdd238659c3740d8 |
---|---|
oai_identifier_str |
oai:scielo:S0103-50532016000601048 |
network_acronym_str |
SBQ-2 |
network_name_str |
Journal of the Brazilian Chemical Society (Online) |
repository_id_str |
|
spelling |
Compounds of Anthostomella brabeji, an Endophytic Fungus Isolated from Paepalanthus planifolius (Eriocaulaceae)Anthostomella brabejiendophytic fungusantimicrobial activityPaepalanthus planifoliusIn this study, fifteen endophytic fungi were isolated from Paepalanthus planifolius (Eriocaulaceae). From the capitula, seven endophytes were screened and evaluated for their metabolomic profile and radical scavenging activity (2,2-diphenyl-1-picrylhydrazyl (DPPH) assay). Chemical investigation of ethyl acetate extract of the endophytic fungus Anthostomella brabeji resulted in the isolation of one new compound, (+)-(6R*,7S*,8R*)-6,7,8-trihydroxy-2,2-dimethyl-5,6,7,8-tetrahydro-chroman-4-one, and three known compounds: 6-hydroxy-2,2-dimethyl-5,6,7,8-tetrahydro-7,8-epoxycroman-4-one, siccayne and eutypinol. All of the compound structures were elucidated using 1D and 2D nuclear magnetic resonance (NMR) and mass spectrometry (MS) analyses. The antimicrobial activity of the compounds and A. brabeji extract were assayed against the microorganisms Staphylococcus aureus, Escherichia coli, Salmonella setubal and Candida albicans. Measured minimal inhibitory concentration (MIC) values ranged from 31.25 to 1000.0 µg mL-1.Sociedade Brasileira de Química2016-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532016000601048Journal of the Brazilian Chemical Society v.27 n.6 2016reponame:Journal of the Brazilian Chemical Society (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.5935/0103-5053.20150362info:eu-repo/semantics/openAccessAmorim,Marcelo R. deSomensi,AndressaAraujo,Angela R.Bonifácio,Bruna V.Bauab,Tais M.Santos,Lourdes C. doseng2016-06-21T00:00:00Zoai:scielo:S0103-50532016000601048Revistahttp://jbcs.sbq.org.brONGhttps://old.scielo.br/oai/scielo-oai.php||office@jbcs.sbq.org.br1678-47900103-5053opendoar:2016-06-21T00:00Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ)false |
dc.title.none.fl_str_mv |
Compounds of Anthostomella brabeji, an Endophytic Fungus Isolated from Paepalanthus planifolius (Eriocaulaceae) |
title |
Compounds of Anthostomella brabeji, an Endophytic Fungus Isolated from Paepalanthus planifolius (Eriocaulaceae) |
spellingShingle |
Compounds of Anthostomella brabeji, an Endophytic Fungus Isolated from Paepalanthus planifolius (Eriocaulaceae) Amorim,Marcelo R. de Anthostomella brabeji endophytic fungus antimicrobial activity Paepalanthus planifolius |
title_short |
Compounds of Anthostomella brabeji, an Endophytic Fungus Isolated from Paepalanthus planifolius (Eriocaulaceae) |
title_full |
Compounds of Anthostomella brabeji, an Endophytic Fungus Isolated from Paepalanthus planifolius (Eriocaulaceae) |
title_fullStr |
Compounds of Anthostomella brabeji, an Endophytic Fungus Isolated from Paepalanthus planifolius (Eriocaulaceae) |
title_full_unstemmed |
Compounds of Anthostomella brabeji, an Endophytic Fungus Isolated from Paepalanthus planifolius (Eriocaulaceae) |
title_sort |
Compounds of Anthostomella brabeji, an Endophytic Fungus Isolated from Paepalanthus planifolius (Eriocaulaceae) |
author |
Amorim,Marcelo R. de |
author_facet |
Amorim,Marcelo R. de Somensi,Andressa Araujo,Angela R. Bonifácio,Bruna V. Bauab,Tais M. Santos,Lourdes C. dos |
author_role |
author |
author2 |
Somensi,Andressa Araujo,Angela R. Bonifácio,Bruna V. Bauab,Tais M. Santos,Lourdes C. dos |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Amorim,Marcelo R. de Somensi,Andressa Araujo,Angela R. Bonifácio,Bruna V. Bauab,Tais M. Santos,Lourdes C. dos |
dc.subject.por.fl_str_mv |
Anthostomella brabeji endophytic fungus antimicrobial activity Paepalanthus planifolius |
topic |
Anthostomella brabeji endophytic fungus antimicrobial activity Paepalanthus planifolius |
description |
In this study, fifteen endophytic fungi were isolated from Paepalanthus planifolius (Eriocaulaceae). From the capitula, seven endophytes were screened and evaluated for their metabolomic profile and radical scavenging activity (2,2-diphenyl-1-picrylhydrazyl (DPPH) assay). Chemical investigation of ethyl acetate extract of the endophytic fungus Anthostomella brabeji resulted in the isolation of one new compound, (+)-(6R*,7S*,8R*)-6,7,8-trihydroxy-2,2-dimethyl-5,6,7,8-tetrahydro-chroman-4-one, and three known compounds: 6-hydroxy-2,2-dimethyl-5,6,7,8-tetrahydro-7,8-epoxycroman-4-one, siccayne and eutypinol. All of the compound structures were elucidated using 1D and 2D nuclear magnetic resonance (NMR) and mass spectrometry (MS) analyses. The antimicrobial activity of the compounds and A. brabeji extract were assayed against the microorganisms Staphylococcus aureus, Escherichia coli, Salmonella setubal and Candida albicans. Measured minimal inhibitory concentration (MIC) values ranged from 31.25 to 1000.0 µg mL-1. |
publishDate |
2016 |
dc.date.none.fl_str_mv |
2016-06-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532016000601048 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532016000601048 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.5935/0103-5053.20150362 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Química |
publisher.none.fl_str_mv |
Sociedade Brasileira de Química |
dc.source.none.fl_str_mv |
Journal of the Brazilian Chemical Society v.27 n.6 2016 reponame:Journal of the Brazilian Chemical Society (Online) instname:Sociedade Brasileira de Química (SBQ) instacron:SBQ |
instname_str |
Sociedade Brasileira de Química (SBQ) |
instacron_str |
SBQ |
institution |
SBQ |
reponame_str |
Journal of the Brazilian Chemical Society (Online) |
collection |
Journal of the Brazilian Chemical Society (Online) |
repository.name.fl_str_mv |
Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ) |
repository.mail.fl_str_mv |
||office@jbcs.sbq.org.br |
_version_ |
1750318178356953088 |