NH4Cl-CH3OH: an efficient, acid- and metal-free catalyst system for the synthesis of quinoxalines
Autor(a) principal: | |
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Data de Publicação: | 2008 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Journal of the Brazilian Chemical Society (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532008000800028 |
Resumo: | The direct condensation of various benzene-1,2-diamines [4-R-Ph-(NH2)2, where R = H, Me, Cl and NO2] and 1,2-dicarbonyl compounds (R'-CO-CO-R', where R' = Ph, 4-MeO-Ph and Me) has been successfully achieved mostly in excellent yields (95-100%) using (NH4Cl-CH3OH) as a mild, efficient, cost-effective, readily available, acid-free, metal-free and eco-friendly catalyst system at room temperature. The procedure can be performed for a broad scope of quinoxalines, however, the nature of the functional group on the aromatic ring of 1,2-diamine exerts a strong influence on the time and the reaction yield. The condensation efficiency could be further regulated by the amount of catalyst and reaction time. |
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NH4Cl-CH3OH: an efficient, acid- and metal-free catalyst system for the synthesis of quinoxalinesquinoxalinesammonium chloride-methanoleco-friendly catalyst systemroom temperatureThe direct condensation of various benzene-1,2-diamines [4-R-Ph-(NH2)2, where R = H, Me, Cl and NO2] and 1,2-dicarbonyl compounds (R'-CO-CO-R', where R' = Ph, 4-MeO-Ph and Me) has been successfully achieved mostly in excellent yields (95-100%) using (NH4Cl-CH3OH) as a mild, efficient, cost-effective, readily available, acid-free, metal-free and eco-friendly catalyst system at room temperature. The procedure can be performed for a broad scope of quinoxalines, however, the nature of the functional group on the aromatic ring of 1,2-diamine exerts a strong influence on the time and the reaction yield. The condensation efficiency could be further regulated by the amount of catalyst and reaction time.Sociedade Brasileira de Química2008-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532008000800028Journal of the Brazilian Chemical Society v.19 n.8 2008reponame:Journal of the Brazilian Chemical Society (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.1590/S0103-50532008000800028info:eu-repo/semantics/openAccessDarabi,Hossein RezaTahoori,FatemehAghapoor,KioumarsTaala,FatemehMohsenzadeh,Farshideng2008-12-09T00:00:00Zoai:scielo:S0103-50532008000800028Revistahttp://jbcs.sbq.org.brONGhttps://old.scielo.br/oai/scielo-oai.php||office@jbcs.sbq.org.br1678-47900103-5053opendoar:2008-12-09T00:00Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ)false |
dc.title.none.fl_str_mv |
NH4Cl-CH3OH: an efficient, acid- and metal-free catalyst system for the synthesis of quinoxalines |
title |
NH4Cl-CH3OH: an efficient, acid- and metal-free catalyst system for the synthesis of quinoxalines |
spellingShingle |
NH4Cl-CH3OH: an efficient, acid- and metal-free catalyst system for the synthesis of quinoxalines Darabi,Hossein Reza quinoxalines ammonium chloride-methanol eco-friendly catalyst system room temperature |
title_short |
NH4Cl-CH3OH: an efficient, acid- and metal-free catalyst system for the synthesis of quinoxalines |
title_full |
NH4Cl-CH3OH: an efficient, acid- and metal-free catalyst system for the synthesis of quinoxalines |
title_fullStr |
NH4Cl-CH3OH: an efficient, acid- and metal-free catalyst system for the synthesis of quinoxalines |
title_full_unstemmed |
NH4Cl-CH3OH: an efficient, acid- and metal-free catalyst system for the synthesis of quinoxalines |
title_sort |
NH4Cl-CH3OH: an efficient, acid- and metal-free catalyst system for the synthesis of quinoxalines |
author |
Darabi,Hossein Reza |
author_facet |
Darabi,Hossein Reza Tahoori,Fatemeh Aghapoor,Kioumars Taala,Fatemeh Mohsenzadeh,Farshid |
author_role |
author |
author2 |
Tahoori,Fatemeh Aghapoor,Kioumars Taala,Fatemeh Mohsenzadeh,Farshid |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Darabi,Hossein Reza Tahoori,Fatemeh Aghapoor,Kioumars Taala,Fatemeh Mohsenzadeh,Farshid |
dc.subject.por.fl_str_mv |
quinoxalines ammonium chloride-methanol eco-friendly catalyst system room temperature |
topic |
quinoxalines ammonium chloride-methanol eco-friendly catalyst system room temperature |
description |
The direct condensation of various benzene-1,2-diamines [4-R-Ph-(NH2)2, where R = H, Me, Cl and NO2] and 1,2-dicarbonyl compounds (R'-CO-CO-R', where R' = Ph, 4-MeO-Ph and Me) has been successfully achieved mostly in excellent yields (95-100%) using (NH4Cl-CH3OH) as a mild, efficient, cost-effective, readily available, acid-free, metal-free and eco-friendly catalyst system at room temperature. The procedure can be performed for a broad scope of quinoxalines, however, the nature of the functional group on the aromatic ring of 1,2-diamine exerts a strong influence on the time and the reaction yield. The condensation efficiency could be further regulated by the amount of catalyst and reaction time. |
publishDate |
2008 |
dc.date.none.fl_str_mv |
2008-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532008000800028 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532008000800028 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0103-50532008000800028 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Química |
publisher.none.fl_str_mv |
Sociedade Brasileira de Química |
dc.source.none.fl_str_mv |
Journal of the Brazilian Chemical Society v.19 n.8 2008 reponame:Journal of the Brazilian Chemical Society (Online) instname:Sociedade Brasileira de Química (SBQ) instacron:SBQ |
instname_str |
Sociedade Brasileira de Química (SBQ) |
instacron_str |
SBQ |
institution |
SBQ |
reponame_str |
Journal of the Brazilian Chemical Society (Online) |
collection |
Journal of the Brazilian Chemical Society (Online) |
repository.name.fl_str_mv |
Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ) |
repository.mail.fl_str_mv |
||office@jbcs.sbq.org.br |
_version_ |
1750318169415745536 |