Warmingiins A and B, Two New Dimeric Naphthoquinone Derivatives from Sinningia warmingii (Gesneriaceae)

Detalhes bibliográficos
Autor(a) principal: Winiewski,Vanessa
Data de Publicação: 2017
Outros Autores: Verdan,Maria Helena, Ribeiro,Marcos A., Hernandez-Tasco,Alvaro J., Salvador,Marcos J., Stefanello,Maria Elida A.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Journal of the Brazilian Chemical Society (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532017000400598
Resumo: Chemical investigation of Sinningia warmingii (Gesneriaceae) tubers lead to the isolation of two new dimeric naphthoquinone derivatives, named warmingiins A and B, besides six known compounds, aggregatin E, aggregatin F, tectoquinone, halleridone, cleroindicin B, and cornoside. All compounds were identified by spectroscopic analysis, mainly nuclear magnetic resonance (NMR) and mass spectrometry (MS), and comparison with the literature. The structure of the warmingiin A, which is an artifact of warmingiin B, was confirmed by X-ray diffraction analysis. Antimicrobial activity of the ethanolic extract and fractions of S. warmingii was evaluated against Staphylococcus aureus, S. epidermidis, Escherichia coli, Pseudomonas aeruginosa, Candida albicans, C. dubliniensis, C. glabrata and C. parapsilosis. All samples were inactive.
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spelling Warmingiins A and B, Two New Dimeric Naphthoquinone Derivatives from Sinningia warmingii (Gesneriaceae)GesneriaceaeSinningia warmingiinaphthoquinone derivativeantimicrobial evaluationChemical investigation of Sinningia warmingii (Gesneriaceae) tubers lead to the isolation of two new dimeric naphthoquinone derivatives, named warmingiins A and B, besides six known compounds, aggregatin E, aggregatin F, tectoquinone, halleridone, cleroindicin B, and cornoside. All compounds were identified by spectroscopic analysis, mainly nuclear magnetic resonance (NMR) and mass spectrometry (MS), and comparison with the literature. The structure of the warmingiin A, which is an artifact of warmingiin B, was confirmed by X-ray diffraction analysis. Antimicrobial activity of the ethanolic extract and fractions of S. warmingii was evaluated against Staphylococcus aureus, S. epidermidis, Escherichia coli, Pseudomonas aeruginosa, Candida albicans, C. dubliniensis, C. glabrata and C. parapsilosis. All samples were inactive.Sociedade Brasileira de Química2017-04-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532017000400598Journal of the Brazilian Chemical Society v.28 n.4 2017reponame:Journal of the Brazilian Chemical Society (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.21577/0103-5053.20160204info:eu-repo/semantics/openAccessWiniewski,VanessaVerdan,Maria HelenaRibeiro,Marcos A.Hernandez-Tasco,Alvaro J.Salvador,Marcos J.Stefanello,Maria Elida A.eng2017-03-06T00:00:00Zoai:scielo:S0103-50532017000400598Revistahttp://jbcs.sbq.org.brONGhttps://old.scielo.br/oai/scielo-oai.php||office@jbcs.sbq.org.br1678-47900103-5053opendoar:2017-03-06T00:00Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ)false
dc.title.none.fl_str_mv Warmingiins A and B, Two New Dimeric Naphthoquinone Derivatives from Sinningia warmingii (Gesneriaceae)
title Warmingiins A and B, Two New Dimeric Naphthoquinone Derivatives from Sinningia warmingii (Gesneriaceae)
spellingShingle Warmingiins A and B, Two New Dimeric Naphthoquinone Derivatives from Sinningia warmingii (Gesneriaceae)
Winiewski,Vanessa
Gesneriaceae
Sinningia warmingii
naphthoquinone derivative
antimicrobial evaluation
title_short Warmingiins A and B, Two New Dimeric Naphthoquinone Derivatives from Sinningia warmingii (Gesneriaceae)
title_full Warmingiins A and B, Two New Dimeric Naphthoquinone Derivatives from Sinningia warmingii (Gesneriaceae)
title_fullStr Warmingiins A and B, Two New Dimeric Naphthoquinone Derivatives from Sinningia warmingii (Gesneriaceae)
title_full_unstemmed Warmingiins A and B, Two New Dimeric Naphthoquinone Derivatives from Sinningia warmingii (Gesneriaceae)
title_sort Warmingiins A and B, Two New Dimeric Naphthoquinone Derivatives from Sinningia warmingii (Gesneriaceae)
author Winiewski,Vanessa
author_facet Winiewski,Vanessa
Verdan,Maria Helena
Ribeiro,Marcos A.
Hernandez-Tasco,Alvaro J.
Salvador,Marcos J.
Stefanello,Maria Elida A.
author_role author
author2 Verdan,Maria Helena
Ribeiro,Marcos A.
Hernandez-Tasco,Alvaro J.
Salvador,Marcos J.
Stefanello,Maria Elida A.
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Winiewski,Vanessa
Verdan,Maria Helena
Ribeiro,Marcos A.
Hernandez-Tasco,Alvaro J.
Salvador,Marcos J.
Stefanello,Maria Elida A.
dc.subject.por.fl_str_mv Gesneriaceae
Sinningia warmingii
naphthoquinone derivative
antimicrobial evaluation
topic Gesneriaceae
Sinningia warmingii
naphthoquinone derivative
antimicrobial evaluation
description Chemical investigation of Sinningia warmingii (Gesneriaceae) tubers lead to the isolation of two new dimeric naphthoquinone derivatives, named warmingiins A and B, besides six known compounds, aggregatin E, aggregatin F, tectoquinone, halleridone, cleroindicin B, and cornoside. All compounds were identified by spectroscopic analysis, mainly nuclear magnetic resonance (NMR) and mass spectrometry (MS), and comparison with the literature. The structure of the warmingiin A, which is an artifact of warmingiin B, was confirmed by X-ray diffraction analysis. Antimicrobial activity of the ethanolic extract and fractions of S. warmingii was evaluated against Staphylococcus aureus, S. epidermidis, Escherichia coli, Pseudomonas aeruginosa, Candida albicans, C. dubliniensis, C. glabrata and C. parapsilosis. All samples were inactive.
publishDate 2017
dc.date.none.fl_str_mv 2017-04-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532017000400598
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532017000400598
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.21577/0103-5053.20160204
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Química
publisher.none.fl_str_mv Sociedade Brasileira de Química
dc.source.none.fl_str_mv Journal of the Brazilian Chemical Society v.28 n.4 2017
reponame:Journal of the Brazilian Chemical Society (Online)
instname:Sociedade Brasileira de Química (SBQ)
instacron:SBQ
instname_str Sociedade Brasileira de Química (SBQ)
instacron_str SBQ
institution SBQ
reponame_str Journal of the Brazilian Chemical Society (Online)
collection Journal of the Brazilian Chemical Society (Online)
repository.name.fl_str_mv Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ)
repository.mail.fl_str_mv ||office@jbcs.sbq.org.br
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