Chemiluminescence determination of mezlocillin by the luminol-potassium periodate system

Detalhes bibliográficos
Autor(a) principal: Shi,Wen Bing
Data de Publicação: 2008
Outros Autores: Yang,Ji Dong
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Journal of the Brazilian Chemical Society (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532008000600019
Resumo: A new, simple and sensitive method has been proposed for the determination of mezlocillin. It is based on the enhancement of the chemiluminescence (CL) emission generated from the oxidation of luminol in alkaline medium by postassium periodate. The optimization of the experimental and instrumental variables affecting the CL enhancement effect has been carried out using flow-injection system. In the optimum conditions, the method is efficient to determine mezlocillin in the linear range of 0.01-30×10-6 g mL-1 with a detection limit (3σ) of 3.0×10-9 g mL-1 and the relative standard deviation (RSD) is 1.0% for 1.0×10-6 g mL-1 mezlocillin (n=11). It has been successfully applied to the mezlocillin determination in commercial preparations, synthetic samples and biological fluids formulations.
id SBQ-2_a9bc586b47a1733ec3cb4e35f03d1274
oai_identifier_str oai:scielo:S0103-50532008000600019
network_acronym_str SBQ-2
network_name_str Journal of the Brazilian Chemical Society (Online)
repository_id_str
spelling Chemiluminescence determination of mezlocillin by the luminol-potassium periodate systemchemiluminescenceflow injectionmezlocillinA new, simple and sensitive method has been proposed for the determination of mezlocillin. It is based on the enhancement of the chemiluminescence (CL) emission generated from the oxidation of luminol in alkaline medium by postassium periodate. The optimization of the experimental and instrumental variables affecting the CL enhancement effect has been carried out using flow-injection system. In the optimum conditions, the method is efficient to determine mezlocillin in the linear range of 0.01-30×10-6 g mL-1 with a detection limit (3σ) of 3.0×10-9 g mL-1 and the relative standard deviation (RSD) is 1.0% for 1.0×10-6 g mL-1 mezlocillin (n=11). It has been successfully applied to the mezlocillin determination in commercial preparations, synthetic samples and biological fluids formulations.Sociedade Brasileira de Química2008-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532008000600019Journal of the Brazilian Chemical Society v.19 n.6 2008reponame:Journal of the Brazilian Chemical Society (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.1590/S0103-50532008000600019info:eu-repo/semantics/openAccessShi,Wen BingYang,Ji Dongeng2008-09-12T00:00:00Zoai:scielo:S0103-50532008000600019Revistahttp://jbcs.sbq.org.brONGhttps://old.scielo.br/oai/scielo-oai.php||office@jbcs.sbq.org.br1678-47900103-5053opendoar:2008-09-12T00:00Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ)false
dc.title.none.fl_str_mv Chemiluminescence determination of mezlocillin by the luminol-potassium periodate system
title Chemiluminescence determination of mezlocillin by the luminol-potassium periodate system
spellingShingle Chemiluminescence determination of mezlocillin by the luminol-potassium periodate system
Shi,Wen Bing
chemiluminescence
flow injection
mezlocillin
title_short Chemiluminescence determination of mezlocillin by the luminol-potassium periodate system
title_full Chemiluminescence determination of mezlocillin by the luminol-potassium periodate system
title_fullStr Chemiluminescence determination of mezlocillin by the luminol-potassium periodate system
title_full_unstemmed Chemiluminescence determination of mezlocillin by the luminol-potassium periodate system
title_sort Chemiluminescence determination of mezlocillin by the luminol-potassium periodate system
author Shi,Wen Bing
author_facet Shi,Wen Bing
Yang,Ji Dong
author_role author
author2 Yang,Ji Dong
author2_role author
dc.contributor.author.fl_str_mv Shi,Wen Bing
Yang,Ji Dong
dc.subject.por.fl_str_mv chemiluminescence
flow injection
mezlocillin
topic chemiluminescence
flow injection
mezlocillin
description A new, simple and sensitive method has been proposed for the determination of mezlocillin. It is based on the enhancement of the chemiluminescence (CL) emission generated from the oxidation of luminol in alkaline medium by postassium periodate. The optimization of the experimental and instrumental variables affecting the CL enhancement effect has been carried out using flow-injection system. In the optimum conditions, the method is efficient to determine mezlocillin in the linear range of 0.01-30×10-6 g mL-1 with a detection limit (3σ) of 3.0×10-9 g mL-1 and the relative standard deviation (RSD) is 1.0% for 1.0×10-6 g mL-1 mezlocillin (n=11). It has been successfully applied to the mezlocillin determination in commercial preparations, synthetic samples and biological fluids formulations.
publishDate 2008
dc.date.none.fl_str_mv 2008-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532008000600019
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532008000600019
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0103-50532008000600019
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Química
publisher.none.fl_str_mv Sociedade Brasileira de Química
dc.source.none.fl_str_mv Journal of the Brazilian Chemical Society v.19 n.6 2008
reponame:Journal of the Brazilian Chemical Society (Online)
instname:Sociedade Brasileira de Química (SBQ)
instacron:SBQ
instname_str Sociedade Brasileira de Química (SBQ)
instacron_str SBQ
institution SBQ
reponame_str Journal of the Brazilian Chemical Society (Online)
collection Journal of the Brazilian Chemical Society (Online)
repository.name.fl_str_mv Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ)
repository.mail.fl_str_mv ||office@jbcs.sbq.org.br
_version_ 1750318169061326848

Registros relacionados