Synthesis, antimicrobial and cytotoxicity studies of some novel modified Strobilurin derivatives

Detalhes bibliográficos
Autor(a) principal: Sridhara,Ajjanna M
Data de Publicação: 2011
Outros Autores: Reddy,Kallam R. Venugopala, Keshavayya,Jathi, Ambika,Dasannana Malige S, Gopinath,Vadiraj S, Bose,Prosenjit, Goud,Sanath Kumar, Peethambar,Sanenahalli K
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Journal of the Brazilian Chemical Society (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532011000500006
Resumo: A series of some new 3-isoxazoline substituted methyl-3-methoxy-2-(4-oxo-3,4-dihydrophthalazin-1-yl)prop-2-enoate derivatives were designed and synthesized from methyl-(4-oxo-3,4-dihydrophthalazin-1-yl)acetate, which in turn was prepared from phthalic anhydride. The structures of synthesized new compounds were characterized by spectral data and studied for their antimicrobial activities and cytotoxicity. Several of these compounds showed good antimicrobial activity
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spelling Synthesis, antimicrobial and cytotoxicity studies of some novel modified Strobilurin derivativesphthalazin-1(2H)-oneβ-methoxyacrylatestrobilurinsisoxazolineA series of some new 3-isoxazoline substituted methyl-3-methoxy-2-(4-oxo-3,4-dihydrophthalazin-1-yl)prop-2-enoate derivatives were designed and synthesized from methyl-(4-oxo-3,4-dihydrophthalazin-1-yl)acetate, which in turn was prepared from phthalic anhydride. The structures of synthesized new compounds were characterized by spectral data and studied for their antimicrobial activities and cytotoxicity. Several of these compounds showed good antimicrobial activitySociedade Brasileira de Química2011-05-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532011000500006Journal of the Brazilian Chemical Society v.22 n.5 2011reponame:Journal of the Brazilian Chemical Society (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.1590/S0103-50532011000500006info:eu-repo/semantics/openAccessSridhara,Ajjanna MReddy,Kallam R. VenugopalaKeshavayya,JathiAmbika,Dasannana Malige SGopinath,Vadiraj SBose,ProsenjitGoud,Sanath KumarPeethambar,Sanenahalli Keng2011-05-16T00:00:00Zoai:scielo:S0103-50532011000500006Revistahttp://jbcs.sbq.org.brONGhttps://old.scielo.br/oai/scielo-oai.php||office@jbcs.sbq.org.br1678-47900103-5053opendoar:2011-05-16T00:00Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ)false
dc.title.none.fl_str_mv Synthesis, antimicrobial and cytotoxicity studies of some novel modified Strobilurin derivatives
title Synthesis, antimicrobial and cytotoxicity studies of some novel modified Strobilurin derivatives
spellingShingle Synthesis, antimicrobial and cytotoxicity studies of some novel modified Strobilurin derivatives
Sridhara,Ajjanna M
phthalazin-1(2H)-one
β-methoxyacrylate
strobilurins
isoxazoline
title_short Synthesis, antimicrobial and cytotoxicity studies of some novel modified Strobilurin derivatives
title_full Synthesis, antimicrobial and cytotoxicity studies of some novel modified Strobilurin derivatives
title_fullStr Synthesis, antimicrobial and cytotoxicity studies of some novel modified Strobilurin derivatives
title_full_unstemmed Synthesis, antimicrobial and cytotoxicity studies of some novel modified Strobilurin derivatives
title_sort Synthesis, antimicrobial and cytotoxicity studies of some novel modified Strobilurin derivatives
author Sridhara,Ajjanna M
author_facet Sridhara,Ajjanna M
Reddy,Kallam R. Venugopala
Keshavayya,Jathi
Ambika,Dasannana Malige S
Gopinath,Vadiraj S
Bose,Prosenjit
Goud,Sanath Kumar
Peethambar,Sanenahalli K
author_role author
author2 Reddy,Kallam R. Venugopala
Keshavayya,Jathi
Ambika,Dasannana Malige S
Gopinath,Vadiraj S
Bose,Prosenjit
Goud,Sanath Kumar
Peethambar,Sanenahalli K
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Sridhara,Ajjanna M
Reddy,Kallam R. Venugopala
Keshavayya,Jathi
Ambika,Dasannana Malige S
Gopinath,Vadiraj S
Bose,Prosenjit
Goud,Sanath Kumar
Peethambar,Sanenahalli K
dc.subject.por.fl_str_mv phthalazin-1(2H)-one
β-methoxyacrylate
strobilurins
isoxazoline
topic phthalazin-1(2H)-one
β-methoxyacrylate
strobilurins
isoxazoline
description A series of some new 3-isoxazoline substituted methyl-3-methoxy-2-(4-oxo-3,4-dihydrophthalazin-1-yl)prop-2-enoate derivatives were designed and synthesized from methyl-(4-oxo-3,4-dihydrophthalazin-1-yl)acetate, which in turn was prepared from phthalic anhydride. The structures of synthesized new compounds were characterized by spectral data and studied for their antimicrobial activities and cytotoxicity. Several of these compounds showed good antimicrobial activity
publishDate 2011
dc.date.none.fl_str_mv 2011-05-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532011000500006
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532011000500006
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0103-50532011000500006
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Química
publisher.none.fl_str_mv Sociedade Brasileira de Química
dc.source.none.fl_str_mv Journal of the Brazilian Chemical Society v.22 n.5 2011
reponame:Journal of the Brazilian Chemical Society (Online)
instname:Sociedade Brasileira de Química (SBQ)
instacron:SBQ
instname_str Sociedade Brasileira de Química (SBQ)
instacron_str SBQ
institution SBQ
reponame_str Journal of the Brazilian Chemical Society (Online)
collection Journal of the Brazilian Chemical Society (Online)
repository.name.fl_str_mv Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ)
repository.mail.fl_str_mv ||office@jbcs.sbq.org.br
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