Two Dibenzylbutyrolactol Derivatives and Other Chemical Constituents from Aristolochia peltato-deltoidea

• Autor(a) principal: Silva,Ana Paula Freitas da
• Data de Publicação: 1999
• Outros Autores: Palmeira Júnior,Sebastião Ferreira, Conserva,Lucia Maria, Guilhon,Giselle Maria S. Pinheiro
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Journal of the Brazilian Chemical Society (Online)
• Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50531999000200009
• topic: Aristolochia peltato-deltoidea; Aristolochiaceae; benzofuran neolignan; dibenzylbutyrolactol lignans; alpha-tocopherylquinone

The hexane extract from the aerial parts of Aristolochia peltato-deltoidea Hoehne (Aristolochiaceae) afforded two new epimeric lignans of the type dibenzylbutyrolactol, rel-(8R, 8’S, 9S)-3,4-dimethoxy-3’,4’-methylenedioxy-9beta-ethoxy- and rel-(8R, 8’S, 9R)-3,4-dimethoxy-3’,4’-methylenedioxy-9alpha-ethoxy-lignans-8.8’,9.O.9’, besides a benzofuran neolignan, known as eupomatenoid-7, alpha-tocopherylquinone, beta-sitosterol and stigmasterol. From the chloroform extract were isolated two diastereomeric dibenzylbutyrolactone lignans: rel-(8R, 8’R)- and rel-(8R, 8’S)-3,4-dimethoxy-3’,4’-methylenedioxy-9-oxo-lignans-8.8’,9.O.9’. Chemical composition analysis by GC/MS of the non polar fractions from the hexane extract was also carried out and ten components were identified. The structures of the isolated compounds were elucidated utilizing spectrometric methods.