In vitro bioactivity of polymer matrices reinforced with a bioactive glass phase
Autor(a) principal: | |
---|---|
Data de Publicação: | 2000 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Journal of the Brazilian Chemical Society (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532000000100014 |
Resumo: | Composites that can mimic the in vitro bioactive behavior of bioactive glasses were designed to fulfill two main features of bioactive glasses that are responsible for their high bond-to-bone rates: (1) capability of providing ions such as calcium and phosphate to the nearby environment and (2) ideal surface structure that allows fast heterogeneous precipitation of hydroxy-carbonate-apatite (HCA). The novel composites were prepared by incorporating bioactive glass particles into polymer matrices. The in vitro bioactivity test was performed by introducing samples into a buffered solution as well as into a simulated body fluid solution. FTIR was used to evaluate the kinetics of HCA (hydroxy-carbonate-apatite) precipitation. The results showed that the obtained composites can supply ions, such as silicates and phosphates in rates and concentrations comparable or superior than bulk bioactive glasses. Moreover, the surface chemistry of the composites was altered to mimic the surface of bioactive glasses. It was demonstrated that the in vitro bioactivity of the composites was enhanced by chemically modifying polymer surfaces through the introduction of special alkoxysilane groups. |
id |
SBQ-2_cdbf5be5dbd3b29057fa6b4768f5e3ae |
---|---|
oai_identifier_str |
oai:scielo:S0103-50532000000100014 |
network_acronym_str |
SBQ-2 |
network_name_str |
Journal of the Brazilian Chemical Society (Online) |
repository_id_str |
|
spelling |
In vitro bioactivity of polymer matrices reinforced with a bioactive glass phasebioactive polymer compositesbiomaterialsComposites that can mimic the in vitro bioactive behavior of bioactive glasses were designed to fulfill two main features of bioactive glasses that are responsible for their high bond-to-bone rates: (1) capability of providing ions such as calcium and phosphate to the nearby environment and (2) ideal surface structure that allows fast heterogeneous precipitation of hydroxy-carbonate-apatite (HCA). The novel composites were prepared by incorporating bioactive glass particles into polymer matrices. The in vitro bioactivity test was performed by introducing samples into a buffered solution as well as into a simulated body fluid solution. FTIR was used to evaluate the kinetics of HCA (hydroxy-carbonate-apatite) precipitation. The results showed that the obtained composites can supply ions, such as silicates and phosphates in rates and concentrations comparable or superior than bulk bioactive glasses. Moreover, the surface chemistry of the composites was altered to mimic the surface of bioactive glasses. It was demonstrated that the in vitro bioactivity of the composites was enhanced by chemically modifying polymer surfaces through the introduction of special alkoxysilane groups.Sociedade Brasileira de Química2000-02-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532000000100014Journal of the Brazilian Chemical Society v.11 n.1 2000reponame:Journal of the Brazilian Chemical Society (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.1590/S0103-50532000000100014info:eu-repo/semantics/openAccessOréfice,Rodrigo L.Hench,Larry L.Brennan,Anthony B.eng2000-06-01T00:00:00Zoai:scielo:S0103-50532000000100014Revistahttp://jbcs.sbq.org.brONGhttps://old.scielo.br/oai/scielo-oai.php||office@jbcs.sbq.org.br1678-47900103-5053opendoar:2000-06-01T00:00Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ)false |
dc.title.none.fl_str_mv |
In vitro bioactivity of polymer matrices reinforced with a bioactive glass phase |
title |
In vitro bioactivity of polymer matrices reinforced with a bioactive glass phase |
spellingShingle |
In vitro bioactivity of polymer matrices reinforced with a bioactive glass phase Oréfice,Rodrigo L. bioactive polymer composites biomaterials |
title_short |
In vitro bioactivity of polymer matrices reinforced with a bioactive glass phase |
title_full |
In vitro bioactivity of polymer matrices reinforced with a bioactive glass phase |
title_fullStr |
In vitro bioactivity of polymer matrices reinforced with a bioactive glass phase |
title_full_unstemmed |
In vitro bioactivity of polymer matrices reinforced with a bioactive glass phase |
title_sort |
In vitro bioactivity of polymer matrices reinforced with a bioactive glass phase |
author |
Oréfice,Rodrigo L. |
author_facet |
Oréfice,Rodrigo L. Hench,Larry L. Brennan,Anthony B. |
author_role |
author |
author2 |
Hench,Larry L. Brennan,Anthony B. |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
Oréfice,Rodrigo L. Hench,Larry L. Brennan,Anthony B. |
dc.subject.por.fl_str_mv |
bioactive polymer composites biomaterials |
topic |
bioactive polymer composites biomaterials |
description |
Composites that can mimic the in vitro bioactive behavior of bioactive glasses were designed to fulfill two main features of bioactive glasses that are responsible for their high bond-to-bone rates: (1) capability of providing ions such as calcium and phosphate to the nearby environment and (2) ideal surface structure that allows fast heterogeneous precipitation of hydroxy-carbonate-apatite (HCA). The novel composites were prepared by incorporating bioactive glass particles into polymer matrices. The in vitro bioactivity test was performed by introducing samples into a buffered solution as well as into a simulated body fluid solution. FTIR was used to evaluate the kinetics of HCA (hydroxy-carbonate-apatite) precipitation. The results showed that the obtained composites can supply ions, such as silicates and phosphates in rates and concentrations comparable or superior than bulk bioactive glasses. Moreover, the surface chemistry of the composites was altered to mimic the surface of bioactive glasses. It was demonstrated that the in vitro bioactivity of the composites was enhanced by chemically modifying polymer surfaces through the introduction of special alkoxysilane groups. |
publishDate |
2000 |
dc.date.none.fl_str_mv |
2000-02-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532000000100014 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532000000100014 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0103-50532000000100014 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Química |
publisher.none.fl_str_mv |
Sociedade Brasileira de Química |
dc.source.none.fl_str_mv |
Journal of the Brazilian Chemical Society v.11 n.1 2000 reponame:Journal of the Brazilian Chemical Society (Online) instname:Sociedade Brasileira de Química (SBQ) instacron:SBQ |
instname_str |
Sociedade Brasileira de Química (SBQ) |
instacron_str |
SBQ |
institution |
SBQ |
reponame_str |
Journal of the Brazilian Chemical Society (Online) |
collection |
Journal of the Brazilian Chemical Society (Online) |
repository.name.fl_str_mv |
Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ) |
repository.mail.fl_str_mv |
||office@jbcs.sbq.org.br |
_version_ |
1750318163840466944 |