Antimicrobial Ellagitannin of Punica granatum Fruits
Autor(a) principal: | |
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Data de Publicação: | 2002 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Journal of the Brazilian Chemical Society (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532002000500010 |
Resumo: | The ethyl acetate extract of Punica granatum fruits was fractionated by chromatographic techniques to afford the ellagitannin punicalagin. The substance was found to be active against methicillin-resistant Staphylococcus aureus strains and was identified by HPLC/UV and ¹HNMR. The antibacterial assays which guided the isolation of the tannin were conducted using the disc diffusion method. Minimum inhibitory concentration (MIC) was determined by the dilution method according to NCCLS (National Committee for Clinical Laboratory Standards) procedure. |
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Journal of the Brazilian Chemical Society (Online) |
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Antimicrobial Ellagitannin of Punica granatum FruitsPunica granatumpunicalaginantimicrobial activityThe ethyl acetate extract of Punica granatum fruits was fractionated by chromatographic techniques to afford the ellagitannin punicalagin. The substance was found to be active against methicillin-resistant Staphylococcus aureus strains and was identified by HPLC/UV and ¹HNMR. The antibacterial assays which guided the isolation of the tannin were conducted using the disc diffusion method. Minimum inhibitory concentration (MIC) was determined by the dilution method according to NCCLS (National Committee for Clinical Laboratory Standards) procedure.Sociedade Brasileira de Química2002-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532002000500010Journal of the Brazilian Chemical Society v.13 n.5 2002reponame:Journal of the Brazilian Chemical Society (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.1590/S0103-50532002000500010info:eu-repo/semantics/openAccessMachado,Thelma de B.Leal,Ivana C. R.Amaral,Ana Claudia F.Santos,Kátia R. N. dosSilva,Marlei G. daKuster,Ricardo M.eng2008-10-08T00:00:00Zoai:scielo:S0103-50532002000500010Revistahttp://jbcs.sbq.org.brONGhttps://old.scielo.br/oai/scielo-oai.php||office@jbcs.sbq.org.br1678-47900103-5053opendoar:2008-10-08T00:00Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ)false |
dc.title.none.fl_str_mv |
Antimicrobial Ellagitannin of Punica granatum Fruits |
title |
Antimicrobial Ellagitannin of Punica granatum Fruits |
spellingShingle |
Antimicrobial Ellagitannin of Punica granatum Fruits Machado,Thelma de B. Punica granatum punicalagin antimicrobial activity |
title_short |
Antimicrobial Ellagitannin of Punica granatum Fruits |
title_full |
Antimicrobial Ellagitannin of Punica granatum Fruits |
title_fullStr |
Antimicrobial Ellagitannin of Punica granatum Fruits |
title_full_unstemmed |
Antimicrobial Ellagitannin of Punica granatum Fruits |
title_sort |
Antimicrobial Ellagitannin of Punica granatum Fruits |
author |
Machado,Thelma de B. |
author_facet |
Machado,Thelma de B. Leal,Ivana C. R. Amaral,Ana Claudia F. Santos,Kátia R. N. dos Silva,Marlei G. da Kuster,Ricardo M. |
author_role |
author |
author2 |
Leal,Ivana C. R. Amaral,Ana Claudia F. Santos,Kátia R. N. dos Silva,Marlei G. da Kuster,Ricardo M. |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Machado,Thelma de B. Leal,Ivana C. R. Amaral,Ana Claudia F. Santos,Kátia R. N. dos Silva,Marlei G. da Kuster,Ricardo M. |
dc.subject.por.fl_str_mv |
Punica granatum punicalagin antimicrobial activity |
topic |
Punica granatum punicalagin antimicrobial activity |
description |
The ethyl acetate extract of Punica granatum fruits was fractionated by chromatographic techniques to afford the ellagitannin punicalagin. The substance was found to be active against methicillin-resistant Staphylococcus aureus strains and was identified by HPLC/UV and ¹HNMR. The antibacterial assays which guided the isolation of the tannin were conducted using the disc diffusion method. Minimum inhibitory concentration (MIC) was determined by the dilution method according to NCCLS (National Committee for Clinical Laboratory Standards) procedure. |
publishDate |
2002 |
dc.date.none.fl_str_mv |
2002-09-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532002000500010 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532002000500010 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0103-50532002000500010 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Química |
publisher.none.fl_str_mv |
Sociedade Brasileira de Química |
dc.source.none.fl_str_mv |
Journal of the Brazilian Chemical Society v.13 n.5 2002 reponame:Journal of the Brazilian Chemical Society (Online) instname:Sociedade Brasileira de Química (SBQ) instacron:SBQ |
instname_str |
Sociedade Brasileira de Química (SBQ) |
instacron_str |
SBQ |
institution |
SBQ |
reponame_str |
Journal of the Brazilian Chemical Society (Online) |
collection |
Journal of the Brazilian Chemical Society (Online) |
repository.name.fl_str_mv |
Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ) |
repository.mail.fl_str_mv |
||office@jbcs.sbq.org.br |
_version_ |
1750318164944617472 |