A home-made hybrid system for the simultaneous determination of ergotamine, dipyrone and caffeine in pharmaceutical preparations

Detalhes bibliográficos
Autor(a) principal: Di Nezio,María S.
Data de Publicação: 2007
Outros Autores: Pistonesi,Marcelo F., Centurión,María E., Palomeque,Miriam E., Lista,Adriana G., Fernández Band,Beatriz S.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Journal of the Brazilian Chemical Society (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532007000700020
Resumo: A novel home-made hybrid detection system was designed for simultaneous determination of caffeine (CAF), dipyrone (DIP) and ergotamine (ERG) in pharmaceutical preparations. Thus, ERG was determined by a fluorimetric signal and PLS-1 method for resolving DIP and CAF UV-Vis spectral data was used. The calibration curve for ERG was linear over the range 2.5-10 mg L-1. The calibration set consisted of 18 mixtures with 0.5 to 4 mg L-1 for CAF, 5 to 20 mg L-1 for DIP and 2.5 and 10 mg L-1 for ERG. Sample preparation prior to analysis was not required. A recovery study with the real samples was carried out and the obtained results were highly satisfactory.
id SBQ-2_e07e90cdbe96364a5d1f380d936261de
oai_identifier_str oai:scielo:S0103-50532007000700020
network_acronym_str SBQ-2
network_name_str Journal of the Brazilian Chemical Society (Online)
repository_id_str
spelling A home-made hybrid system for the simultaneous determination of ergotamine, dipyrone and caffeine in pharmaceutical preparationshybrid systemergotaminedipyronecaffeinesimultaneous determination, PLS-1A novel home-made hybrid detection system was designed for simultaneous determination of caffeine (CAF), dipyrone (DIP) and ergotamine (ERG) in pharmaceutical preparations. Thus, ERG was determined by a fluorimetric signal and PLS-1 method for resolving DIP and CAF UV-Vis spectral data was used. The calibration curve for ERG was linear over the range 2.5-10 mg L-1. The calibration set consisted of 18 mixtures with 0.5 to 4 mg L-1 for CAF, 5 to 20 mg L-1 for DIP and 2.5 and 10 mg L-1 for ERG. Sample preparation prior to analysis was not required. A recovery study with the real samples was carried out and the obtained results were highly satisfactory.Sociedade Brasileira de Química2007-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532007000700020Journal of the Brazilian Chemical Society v.18 n.7 2007reponame:Journal of the Brazilian Chemical Society (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.1590/S0103-50532007000700020info:eu-repo/semantics/openAccessDi Nezio,María S.Pistonesi,Marcelo F.Centurión,María E.Palomeque,Miriam E.Lista,Adriana G.Fernández Band,Beatriz S.eng2008-01-08T00:00:00Zoai:scielo:S0103-50532007000700020Revistahttp://jbcs.sbq.org.brONGhttps://old.scielo.br/oai/scielo-oai.php||office@jbcs.sbq.org.br1678-47900103-5053opendoar:2008-01-08T00:00Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ)false
dc.title.none.fl_str_mv A home-made hybrid system for the simultaneous determination of ergotamine, dipyrone and caffeine in pharmaceutical preparations
title A home-made hybrid system for the simultaneous determination of ergotamine, dipyrone and caffeine in pharmaceutical preparations
spellingShingle A home-made hybrid system for the simultaneous determination of ergotamine, dipyrone and caffeine in pharmaceutical preparations
Di Nezio,María S.
hybrid system
ergotamine
dipyrone
caffeine
simultaneous determination, PLS-1
title_short A home-made hybrid system for the simultaneous determination of ergotamine, dipyrone and caffeine in pharmaceutical preparations
title_full A home-made hybrid system for the simultaneous determination of ergotamine, dipyrone and caffeine in pharmaceutical preparations
title_fullStr A home-made hybrid system for the simultaneous determination of ergotamine, dipyrone and caffeine in pharmaceutical preparations
title_full_unstemmed A home-made hybrid system for the simultaneous determination of ergotamine, dipyrone and caffeine in pharmaceutical preparations
title_sort A home-made hybrid system for the simultaneous determination of ergotamine, dipyrone and caffeine in pharmaceutical preparations
author Di Nezio,María S.
author_facet Di Nezio,María S.
Pistonesi,Marcelo F.
Centurión,María E.
Palomeque,Miriam E.
Lista,Adriana G.
Fernández Band,Beatriz S.
author_role author
author2 Pistonesi,Marcelo F.
Centurión,María E.
Palomeque,Miriam E.
Lista,Adriana G.
Fernández Band,Beatriz S.
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Di Nezio,María S.
Pistonesi,Marcelo F.
Centurión,María E.
Palomeque,Miriam E.
Lista,Adriana G.
Fernández Band,Beatriz S.
dc.subject.por.fl_str_mv hybrid system
ergotamine
dipyrone
caffeine
simultaneous determination, PLS-1
topic hybrid system
ergotamine
dipyrone
caffeine
simultaneous determination, PLS-1
description A novel home-made hybrid detection system was designed for simultaneous determination of caffeine (CAF), dipyrone (DIP) and ergotamine (ERG) in pharmaceutical preparations. Thus, ERG was determined by a fluorimetric signal and PLS-1 method for resolving DIP and CAF UV-Vis spectral data was used. The calibration curve for ERG was linear over the range 2.5-10 mg L-1. The calibration set consisted of 18 mixtures with 0.5 to 4 mg L-1 for CAF, 5 to 20 mg L-1 for DIP and 2.5 and 10 mg L-1 for ERG. Sample preparation prior to analysis was not required. A recovery study with the real samples was carried out and the obtained results were highly satisfactory.
publishDate 2007
dc.date.none.fl_str_mv 2007-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532007000700020
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532007000700020
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0103-50532007000700020
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Química
publisher.none.fl_str_mv Sociedade Brasileira de Química
dc.source.none.fl_str_mv Journal of the Brazilian Chemical Society v.18 n.7 2007
reponame:Journal of the Brazilian Chemical Society (Online)
instname:Sociedade Brasileira de Química (SBQ)
instacron:SBQ
instname_str Sociedade Brasileira de Química (SBQ)
instacron_str SBQ
institution SBQ
reponame_str Journal of the Brazilian Chemical Society (Online)
collection Journal of the Brazilian Chemical Society (Online)
repository.name.fl_str_mv Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ)
repository.mail.fl_str_mv ||office@jbcs.sbq.org.br
_version_ 1750318168532844544

Registros relacionados