Enantioselective transport of R-clenbuterol through a bulk liquid membrane containing O,O'-dibenzoyl-(2S, 3S)-tartaric

Detalhes bibliográficos
Autor(a) principal: Jiao,Feipeng
Data de Publicação: 2007
Outros Autores: Chen,Xiaoqing, Hu,Weiguo, Yang,Ling, Huang,Kelong
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Journal of the Brazilian Chemical Society (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532007000400020
Resumo: A method of bulk liquid membrane (BLM) using O, O'-dibenzoyl-(2S, 3S)-tartaric acid was developed for the enantioselective transport of racemic clenbuterol. The influence of buffer pH, concentration ratio of chiral carrier to clenbuterol were studied. It was an appropriate choice of such as pH 7 in aqueous solution and concentration ratio of 1:4. The model of kinetic transport was established by means of a kinetic model involving two consecutive irreversible first order reactions. The pseudo-first order apparent rate constants were determined. It is helpful for optimizing the transport of BLM systems and realizing the large-scale production of pure enantiomer.
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spelling Enantioselective transport of R-clenbuterol through a bulk liquid membrane containing O,O'-dibenzoyl-(2S, 3S)-tartaricbulk liquid membraneenantioselective transportclenbuterolO, O'-dibenzoyl-(2S, 3S)-tartaric acidkineticsA method of bulk liquid membrane (BLM) using O, O'-dibenzoyl-(2S, 3S)-tartaric acid was developed for the enantioselective transport of racemic clenbuterol. The influence of buffer pH, concentration ratio of chiral carrier to clenbuterol were studied. It was an appropriate choice of such as pH 7 in aqueous solution and concentration ratio of 1:4. The model of kinetic transport was established by means of a kinetic model involving two consecutive irreversible first order reactions. The pseudo-first order apparent rate constants were determined. It is helpful for optimizing the transport of BLM systems and realizing the large-scale production of pure enantiomer.Sociedade Brasileira de Química2007-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532007000400020Journal of the Brazilian Chemical Society v.18 n.4 2007reponame:Journal of the Brazilian Chemical Society (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.1590/S0103-50532007000400020info:eu-repo/semantics/openAccessJiao,FeipengChen,XiaoqingHu,WeiguoYang,LingHuang,Kelongeng2007-09-18T00:00:00Zoai:scielo:S0103-50532007000400020Revistahttp://jbcs.sbq.org.brONGhttps://old.scielo.br/oai/scielo-oai.php||office@jbcs.sbq.org.br1678-47900103-5053opendoar:2007-09-18T00:00Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ)false
dc.title.none.fl_str_mv Enantioselective transport of R-clenbuterol through a bulk liquid membrane containing O,O'-dibenzoyl-(2S, 3S)-tartaric
title Enantioselective transport of R-clenbuterol through a bulk liquid membrane containing O,O'-dibenzoyl-(2S, 3S)-tartaric
spellingShingle Enantioselective transport of R-clenbuterol through a bulk liquid membrane containing O,O'-dibenzoyl-(2S, 3S)-tartaric
Jiao,Feipeng
bulk liquid membrane
enantioselective transport
clenbuterol
O, O'-dibenzoyl-(2S, 3S)-tartaric acid
kinetics
title_short Enantioselective transport of R-clenbuterol through a bulk liquid membrane containing O,O'-dibenzoyl-(2S, 3S)-tartaric
title_full Enantioselective transport of R-clenbuterol through a bulk liquid membrane containing O,O'-dibenzoyl-(2S, 3S)-tartaric
title_fullStr Enantioselective transport of R-clenbuterol through a bulk liquid membrane containing O,O'-dibenzoyl-(2S, 3S)-tartaric
title_full_unstemmed Enantioselective transport of R-clenbuterol through a bulk liquid membrane containing O,O'-dibenzoyl-(2S, 3S)-tartaric
title_sort Enantioselective transport of R-clenbuterol through a bulk liquid membrane containing O,O'-dibenzoyl-(2S, 3S)-tartaric
author Jiao,Feipeng
author_facet Jiao,Feipeng
Chen,Xiaoqing
Hu,Weiguo
Yang,Ling
Huang,Kelong
author_role author
author2 Chen,Xiaoqing
Hu,Weiguo
Yang,Ling
Huang,Kelong
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Jiao,Feipeng
Chen,Xiaoqing
Hu,Weiguo
Yang,Ling
Huang,Kelong
dc.subject.por.fl_str_mv bulk liquid membrane
enantioselective transport
clenbuterol
O, O'-dibenzoyl-(2S, 3S)-tartaric acid
kinetics
topic bulk liquid membrane
enantioselective transport
clenbuterol
O, O'-dibenzoyl-(2S, 3S)-tartaric acid
kinetics
description A method of bulk liquid membrane (BLM) using O, O'-dibenzoyl-(2S, 3S)-tartaric acid was developed for the enantioselective transport of racemic clenbuterol. The influence of buffer pH, concentration ratio of chiral carrier to clenbuterol were studied. It was an appropriate choice of such as pH 7 in aqueous solution and concentration ratio of 1:4. The model of kinetic transport was established by means of a kinetic model involving two consecutive irreversible first order reactions. The pseudo-first order apparent rate constants were determined. It is helpful for optimizing the transport of BLM systems and realizing the large-scale production of pure enantiomer.
publishDate 2007
dc.date.none.fl_str_mv 2007-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532007000400020
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532007000400020
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0103-50532007000400020
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Química
publisher.none.fl_str_mv Sociedade Brasileira de Química
dc.source.none.fl_str_mv Journal of the Brazilian Chemical Society v.18 n.4 2007
reponame:Journal of the Brazilian Chemical Society (Online)
instname:Sociedade Brasileira de Química (SBQ)
instacron:SBQ
instname_str Sociedade Brasileira de Química (SBQ)
instacron_str SBQ
institution SBQ
reponame_str Journal of the Brazilian Chemical Society (Online)
collection Journal of the Brazilian Chemical Society (Online)
repository.name.fl_str_mv Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ)
repository.mail.fl_str_mv ||office@jbcs.sbq.org.br
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