Cytotoxic Chalcones from Desmodium oxyphyllum

Detalhes bibliográficos
Autor(a) principal: Gao,Xue-Mei
Data de Publicação: 2015
Outros Autores: Wang,Huan, Li,Yin-Ke, Ji,Bing-Kun, Xia,Cong-Fang, Yang,Juan-Xia, Zhou,Min, Ye,Yan-Qing, Hu,Qiu-Fen
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Journal of the Brazilian Chemical Society (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532015000400736
Resumo: Three new chalcones were isolated from Desmodium oxyphyllum. Their structures were elucidated by spectroscopic methods including extensive 1D- and 2D-nuclear magnetic ressonance techniques. The compounds were evaluated for their cytotoxicity against five human tumor cell lines (NB4, A549, SHSY5Y, PC3, and MCF7). The results showed that the compounds exhibited weak cytotoxicity against some selected cell lines with IC50 values ranging from 3.6 to 8.9 μM.
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spelling Cytotoxic Chalcones from Desmodium oxyphyllumchalconescytotoxicityDesmodium oxyphyllumThree new chalcones were isolated from Desmodium oxyphyllum. Their structures were elucidated by spectroscopic methods including extensive 1D- and 2D-nuclear magnetic ressonance techniques. The compounds were evaluated for their cytotoxicity against five human tumor cell lines (NB4, A549, SHSY5Y, PC3, and MCF7). The results showed that the compounds exhibited weak cytotoxicity against some selected cell lines with IC50 values ranging from 3.6 to 8.9 μM.Sociedade Brasileira de Química2015-04-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532015000400736Journal of the Brazilian Chemical Society v.26 n.4 2015reponame:Journal of the Brazilian Chemical Society (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.5935/0103-5053.20150034info:eu-repo/semantics/openAccessGao,Xue-MeiWang,HuanLi,Yin-KeJi,Bing-KunXia,Cong-FangYang,Juan-XiaZhou,MinYe,Yan-QingHu,Qiu-Feneng2015-05-11T00:00:00Zoai:scielo:S0103-50532015000400736Revistahttp://jbcs.sbq.org.brONGhttps://old.scielo.br/oai/scielo-oai.php||office@jbcs.sbq.org.br1678-47900103-5053opendoar:2015-05-11T00:00Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ)false
dc.title.none.fl_str_mv Cytotoxic Chalcones from Desmodium oxyphyllum
title Cytotoxic Chalcones from Desmodium oxyphyllum
spellingShingle Cytotoxic Chalcones from Desmodium oxyphyllum
Gao,Xue-Mei
chalcones
cytotoxicity
Desmodium oxyphyllum
title_short Cytotoxic Chalcones from Desmodium oxyphyllum
title_full Cytotoxic Chalcones from Desmodium oxyphyllum
title_fullStr Cytotoxic Chalcones from Desmodium oxyphyllum
title_full_unstemmed Cytotoxic Chalcones from Desmodium oxyphyllum
title_sort Cytotoxic Chalcones from Desmodium oxyphyllum
author Gao,Xue-Mei
author_facet Gao,Xue-Mei
Wang,Huan
Li,Yin-Ke
Ji,Bing-Kun
Xia,Cong-Fang
Yang,Juan-Xia
Zhou,Min
Ye,Yan-Qing
Hu,Qiu-Fen
author_role author
author2 Wang,Huan
Li,Yin-Ke
Ji,Bing-Kun
Xia,Cong-Fang
Yang,Juan-Xia
Zhou,Min
Ye,Yan-Qing
Hu,Qiu-Fen
author2_role author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Gao,Xue-Mei
Wang,Huan
Li,Yin-Ke
Ji,Bing-Kun
Xia,Cong-Fang
Yang,Juan-Xia
Zhou,Min
Ye,Yan-Qing
Hu,Qiu-Fen
dc.subject.por.fl_str_mv chalcones
cytotoxicity
Desmodium oxyphyllum
topic chalcones
cytotoxicity
Desmodium oxyphyllum
description Three new chalcones were isolated from Desmodium oxyphyllum. Their structures were elucidated by spectroscopic methods including extensive 1D- and 2D-nuclear magnetic ressonance techniques. The compounds were evaluated for their cytotoxicity against five human tumor cell lines (NB4, A549, SHSY5Y, PC3, and MCF7). The results showed that the compounds exhibited weak cytotoxicity against some selected cell lines with IC50 values ranging from 3.6 to 8.9 μM.
publishDate 2015
dc.date.none.fl_str_mv 2015-04-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532015000400736
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532015000400736
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.5935/0103-5053.20150034
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Química
publisher.none.fl_str_mv Sociedade Brasileira de Química
dc.source.none.fl_str_mv Journal of the Brazilian Chemical Society v.26 n.4 2015
reponame:Journal of the Brazilian Chemical Society (Online)
instname:Sociedade Brasileira de Química (SBQ)
instacron:SBQ
instname_str Sociedade Brasileira de Química (SBQ)
instacron_str SBQ
institution SBQ
reponame_str Journal of the Brazilian Chemical Society (Online)
collection Journal of the Brazilian Chemical Society (Online)
repository.name.fl_str_mv Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ)
repository.mail.fl_str_mv ||office@jbcs.sbq.org.br
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