Factors influencing codon usage bias in genomes

Detalhes bibliográficos
Autor(a) principal: Salim,Hannah M. W.
Data de Publicação: 2008
Outros Autores: Cavalcanti,Andre R. O.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Journal of the Brazilian Chemical Society (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532008000200008
Resumo: The genetic code is degenerate, i.e. some amino acids are coded for by more than one codon. Although coding for the same amino acid, synonymous codons are not equally used in different genomes, and even in a single genome the synonymous codon usage can vary widely among genes, or even along the gene sequences. With the recent advent of full genome sequences we are starting to unravel the reasons for these deviations. In this review we will cover some of the proposed factors that might cause different codon usage bias and the selective forces influencing it.
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spelling Factors influencing codon usage bias in genomescodon usagecodon biastranslationexpression levelselectionThe genetic code is degenerate, i.e. some amino acids are coded for by more than one codon. Although coding for the same amino acid, synonymous codons are not equally used in different genomes, and even in a single genome the synonymous codon usage can vary widely among genes, or even along the gene sequences. With the recent advent of full genome sequences we are starting to unravel the reasons for these deviations. In this review we will cover some of the proposed factors that might cause different codon usage bias and the selective forces influencing it.Sociedade Brasileira de Química2008-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532008000200008Journal of the Brazilian Chemical Society v.19 n.2 2008reponame:Journal of the Brazilian Chemical Society (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.1590/S0103-50532008000200008info:eu-repo/semantics/openAccessSalim,Hannah M. W.Cavalcanti,Andre R. O.eng2008-04-08T00:00:00Zoai:scielo:S0103-50532008000200008Revistahttp://jbcs.sbq.org.brONGhttps://old.scielo.br/oai/scielo-oai.php||office@jbcs.sbq.org.br1678-47900103-5053opendoar:2008-04-08T00:00Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ)false
dc.title.none.fl_str_mv Factors influencing codon usage bias in genomes
title Factors influencing codon usage bias in genomes
spellingShingle Factors influencing codon usage bias in genomes
Salim,Hannah M. W.
codon usage
codon bias
translation
expression level
selection
title_short Factors influencing codon usage bias in genomes
title_full Factors influencing codon usage bias in genomes
title_fullStr Factors influencing codon usage bias in genomes
title_full_unstemmed Factors influencing codon usage bias in genomes
title_sort Factors influencing codon usage bias in genomes
author Salim,Hannah M. W.
author_facet Salim,Hannah M. W.
Cavalcanti,Andre R. O.
author_role author
author2 Cavalcanti,Andre R. O.
author2_role author
dc.contributor.author.fl_str_mv Salim,Hannah M. W.
Cavalcanti,Andre R. O.
dc.subject.por.fl_str_mv codon usage
codon bias
translation
expression level
selection
topic codon usage
codon bias
translation
expression level
selection
description The genetic code is degenerate, i.e. some amino acids are coded for by more than one codon. Although coding for the same amino acid, synonymous codons are not equally used in different genomes, and even in a single genome the synonymous codon usage can vary widely among genes, or even along the gene sequences. With the recent advent of full genome sequences we are starting to unravel the reasons for these deviations. In this review we will cover some of the proposed factors that might cause different codon usage bias and the selective forces influencing it.
publishDate 2008
dc.date.none.fl_str_mv 2008-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532008000200008
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532008000200008
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0103-50532008000200008
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Química
publisher.none.fl_str_mv Sociedade Brasileira de Química
dc.source.none.fl_str_mv Journal of the Brazilian Chemical Society v.19 n.2 2008
reponame:Journal of the Brazilian Chemical Society (Online)
instname:Sociedade Brasileira de Química (SBQ)
instacron:SBQ
instname_str Sociedade Brasileira de Química (SBQ)
instacron_str SBQ
institution SBQ
reponame_str Journal of the Brazilian Chemical Society (Online)
collection Journal of the Brazilian Chemical Society (Online)
repository.name.fl_str_mv Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ)
repository.mail.fl_str_mv ||office@jbcs.sbq.org.br
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