16,17-Seco- and 2,3:16,17-di-Seco-pregnanes from Guarea guidonia

Detalhes bibliográficos
Autor(a) principal: Garcez,Walmir Silva
Data de Publicação: 2008
Outros Autores: Garcez,Fernanda Rodrigues, Soares,Luzinátia Ramos
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Journal of the Brazilian Chemical Society (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532008000600004
Resumo: Two new seco- and di-seco-pregnanes, 2α,3β-dihydroxy-16,17-seco-pregn-17-ene-16-oic acid methyl ester 2β,19-hemiketal (1) and 2,3:16,17-di-seco-pregn-17-ene-3-oic acid-16-oic acid methyl ester-19-hydroxy-2-carboxylic acid-2,19-lactone (2), have been obtained from the trunk bark of Guarea guidonia. Their structures have been established by a combination of 1D- and 2D-NMR spectroscopic techniques and MS data. The unique seco- and di-seco-pregnane carbocyclic skeletal types as found in compounds 1 and 2 are being reported in the Meliaceae for the first time as well as the occurrence of pregnanes in the genus Guarea.
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spelling 16,17-Seco- and 2,3:16,17-di-Seco-pregnanes from Guarea guidoniaGuarea guidoniaMeliaceaeseco-pregnanedi-seco-pregnaneTwo new seco- and di-seco-pregnanes, 2α,3β-dihydroxy-16,17-seco-pregn-17-ene-16-oic acid methyl ester 2β,19-hemiketal (1) and 2,3:16,17-di-seco-pregn-17-ene-3-oic acid-16-oic acid methyl ester-19-hydroxy-2-carboxylic acid-2,19-lactone (2), have been obtained from the trunk bark of Guarea guidonia. Their structures have been established by a combination of 1D- and 2D-NMR spectroscopic techniques and MS data. The unique seco- and di-seco-pregnane carbocyclic skeletal types as found in compounds 1 and 2 are being reported in the Meliaceae for the first time as well as the occurrence of pregnanes in the genus Guarea.Sociedade Brasileira de Química2008-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532008000600004Journal of the Brazilian Chemical Society v.19 n.6 2008reponame:Journal of the Brazilian Chemical Society (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.1590/S0103-50532008000600004info:eu-repo/semantics/openAccessGarcez,Walmir SilvaGarcez,Fernanda RodriguesSoares,Luzinátia Ramoseng2008-09-12T00:00:00Zoai:scielo:S0103-50532008000600004Revistahttp://jbcs.sbq.org.brONGhttps://old.scielo.br/oai/scielo-oai.php||office@jbcs.sbq.org.br1678-47900103-5053opendoar:2008-09-12T00:00Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ)false
dc.title.none.fl_str_mv 16,17-Seco- and 2,3:16,17-di-Seco-pregnanes from Guarea guidonia
title 16,17-Seco- and 2,3:16,17-di-Seco-pregnanes from Guarea guidonia
spellingShingle 16,17-Seco- and 2,3:16,17-di-Seco-pregnanes from Guarea guidonia
Garcez,Walmir Silva
Guarea guidonia
Meliaceae
seco-pregnane
di-seco-pregnane
title_short 16,17-Seco- and 2,3:16,17-di-Seco-pregnanes from Guarea guidonia
title_full 16,17-Seco- and 2,3:16,17-di-Seco-pregnanes from Guarea guidonia
title_fullStr 16,17-Seco- and 2,3:16,17-di-Seco-pregnanes from Guarea guidonia
title_full_unstemmed 16,17-Seco- and 2,3:16,17-di-Seco-pregnanes from Guarea guidonia
title_sort 16,17-Seco- and 2,3:16,17-di-Seco-pregnanes from Guarea guidonia
author Garcez,Walmir Silva
author_facet Garcez,Walmir Silva
Garcez,Fernanda Rodrigues
Soares,Luzinátia Ramos
author_role author
author2 Garcez,Fernanda Rodrigues
Soares,Luzinátia Ramos
author2_role author
author
dc.contributor.author.fl_str_mv Garcez,Walmir Silva
Garcez,Fernanda Rodrigues
Soares,Luzinátia Ramos
dc.subject.por.fl_str_mv Guarea guidonia
Meliaceae
seco-pregnane
di-seco-pregnane
topic Guarea guidonia
Meliaceae
seco-pregnane
di-seco-pregnane
description Two new seco- and di-seco-pregnanes, 2α,3β-dihydroxy-16,17-seco-pregn-17-ene-16-oic acid methyl ester 2β,19-hemiketal (1) and 2,3:16,17-di-seco-pregn-17-ene-3-oic acid-16-oic acid methyl ester-19-hydroxy-2-carboxylic acid-2,19-lactone (2), have been obtained from the trunk bark of Guarea guidonia. Their structures have been established by a combination of 1D- and 2D-NMR spectroscopic techniques and MS data. The unique seco- and di-seco-pregnane carbocyclic skeletal types as found in compounds 1 and 2 are being reported in the Meliaceae for the first time as well as the occurrence of pregnanes in the genus Guarea.
publishDate 2008
dc.date.none.fl_str_mv 2008-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532008000600004
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532008000600004
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0103-50532008000600004
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Química
publisher.none.fl_str_mv Sociedade Brasileira de Química
dc.source.none.fl_str_mv Journal of the Brazilian Chemical Society v.19 n.6 2008
reponame:Journal of the Brazilian Chemical Society (Online)
instname:Sociedade Brasileira de Química (SBQ)
instacron:SBQ
instname_str Sociedade Brasileira de Química (SBQ)
instacron_str SBQ
institution SBQ
reponame_str Journal of the Brazilian Chemical Society (Online)
collection Journal of the Brazilian Chemical Society (Online)
repository.name.fl_str_mv Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ)
repository.mail.fl_str_mv ||office@jbcs.sbq.org.br
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