Antioxidantes dietéticos: controvérsias e perspectivas

Detalhes bibliográficos
Autor(a) principal: Cerqueira,Fernanda Menezes
Data de Publicação: 2007
Outros Autores: Medeiros,Marisa Helena Gennari de, Augusto,Ohara
Tipo de documento: Artigo
Idioma: por
Título da fonte: Química Nova (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422007000200036
Resumo: The generation of reactive oxygen and nitrogen species (ROS and RNS) during metabolism is capable of damaging cellular biomolecules. To be protected against oxidative injury, cells evolved complex cellular defense mechanisms and the capability to use exogenous antioxidants to eliminate ROS/RNS. The potential role of micronutrients as antioxidants (vitamin C, vitamin E, carotenoids and poliphenols) has stimulated intense research efforts. In various human supplementation studies, however, these compounds presented pro-oxidant effects at high doses for most risk groups. Therefore, more studies about the bioavailability, tissue uptake, metabolism and biological activities should be performed before establishing recommendations for disease prevention.
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spelling Antioxidantes dietéticos: controvérsias e perspectivasantioxidant vitaminscarotenoidspoliphenolsThe generation of reactive oxygen and nitrogen species (ROS and RNS) during metabolism is capable of damaging cellular biomolecules. To be protected against oxidative injury, cells evolved complex cellular defense mechanisms and the capability to use exogenous antioxidants to eliminate ROS/RNS. The potential role of micronutrients as antioxidants (vitamin C, vitamin E, carotenoids and poliphenols) has stimulated intense research efforts. In various human supplementation studies, however, these compounds presented pro-oxidant effects at high doses for most risk groups. Therefore, more studies about the bioavailability, tissue uptake, metabolism and biological activities should be performed before establishing recommendations for disease prevention.Sociedade Brasileira de Química2007-04-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422007000200036Química Nova v.30 n.2 2007reponame:Química Nova (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.1590/S0100-40422007000200036info:eu-repo/semantics/openAccessCerqueira,Fernanda MenezesMedeiros,Marisa Helena Gennari deAugusto,Oharapor2007-03-13T00:00:00Zoai:scielo:S0100-40422007000200036Revistahttps://www.scielo.br/j/qn/ONGhttps://old.scielo.br/oai/scielo-oai.phpquimicanova@sbq.org.br1678-70640100-4042opendoar:2007-03-13T00:00Química Nova (Online) - Sociedade Brasileira de Química (SBQ)false
dc.title.none.fl_str_mv Antioxidantes dietéticos: controvérsias e perspectivas
title Antioxidantes dietéticos: controvérsias e perspectivas
spellingShingle Antioxidantes dietéticos: controvérsias e perspectivas
Cerqueira,Fernanda Menezes
antioxidant vitamins
carotenoids
poliphenols
title_short Antioxidantes dietéticos: controvérsias e perspectivas
title_full Antioxidantes dietéticos: controvérsias e perspectivas
title_fullStr Antioxidantes dietéticos: controvérsias e perspectivas
title_full_unstemmed Antioxidantes dietéticos: controvérsias e perspectivas
title_sort Antioxidantes dietéticos: controvérsias e perspectivas
author Cerqueira,Fernanda Menezes
author_facet Cerqueira,Fernanda Menezes
Medeiros,Marisa Helena Gennari de
Augusto,Ohara
author_role author
author2 Medeiros,Marisa Helena Gennari de
Augusto,Ohara
author2_role author
author
dc.contributor.author.fl_str_mv Cerqueira,Fernanda Menezes
Medeiros,Marisa Helena Gennari de
Augusto,Ohara
dc.subject.por.fl_str_mv antioxidant vitamins
carotenoids
poliphenols
topic antioxidant vitamins
carotenoids
poliphenols
description The generation of reactive oxygen and nitrogen species (ROS and RNS) during metabolism is capable of damaging cellular biomolecules. To be protected against oxidative injury, cells evolved complex cellular defense mechanisms and the capability to use exogenous antioxidants to eliminate ROS/RNS. The potential role of micronutrients as antioxidants (vitamin C, vitamin E, carotenoids and poliphenols) has stimulated intense research efforts. In various human supplementation studies, however, these compounds presented pro-oxidant effects at high doses for most risk groups. Therefore, more studies about the bioavailability, tissue uptake, metabolism and biological activities should be performed before establishing recommendations for disease prevention.
publishDate 2007
dc.date.none.fl_str_mv 2007-04-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422007000200036
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422007000200036
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv 10.1590/S0100-40422007000200036
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Química
publisher.none.fl_str_mv Sociedade Brasileira de Química
dc.source.none.fl_str_mv Química Nova v.30 n.2 2007
reponame:Química Nova (Online)
instname:Sociedade Brasileira de Química (SBQ)
instacron:SBQ
instname_str Sociedade Brasileira de Química (SBQ)
instacron_str SBQ
institution SBQ
reponame_str Química Nova (Online)
collection Química Nova (Online)
repository.name.fl_str_mv Química Nova (Online) - Sociedade Brasileira de Química (SBQ)
repository.mail.fl_str_mv quimicanova@sbq.org.br
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