DEVELOPMENT AND OPTIMIZATION OF A MICROWAVE-ASSISTED EXTRACTION OF PLUMIERIDE FROM Allamanda cathartica L. FLOWERS

Detalhes bibliográficos
Autor(a) principal: Bonomini,Tiago J.
Data de Publicação: 2018
Outros Autores: Góes,Jaqueline A., Machado,Marina da S., Silva,Ruth M. L. da, Malheiros,Angela
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Química Nova (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422018000100036
Resumo: A simple and efficient microwave-assisted extraction process has been developed in order to extract plumieride from Allamanda cathartica flowers. The extracts have been obtained through microwave-assisted extraction (MAE) process with ethanol and ethyl acetate at different time, power and temperatures. Static maceration at room temperature with ethanol and ethyl acetate was obtained in order to compare the efficiency of extraction. HPLC method was validated to quantify plumieride in the extracts. The analyzed parameters: linearity (R2 = 0.999), precision (CV 3.3%), recovery (98%), specificity (97%), limit of detection (1 µg mL-1), and limit of quantification (2 µg mL-1) were satisfactory. The yield of plumieride reached 43% in the extracts under the optimal MAE conditions (10 min, 300W). Plumieride recoveries by conventional extraction method were 12% with ethanol and 22% with ethyl acetate. Time and power parameters on plumieride extraction yield was determined by applying a factorial design and surface plots. Ethanol was the best extractor solvent and it was possible to obtain high contents (52 mg g-1 of dry flowers) at optimized conditions. It can be concluded that MAE process has actual advantages over the conventional extraction method in terms of shorter time and higher efficiency to recover plumieride from A. cathartica flowers.
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spelling DEVELOPMENT AND OPTIMIZATION OF A MICROWAVE-ASSISTED EXTRACTION OF PLUMIERIDE FROM Allamanda cathartica L. FLOWERSAllamanda catharticahigh performance liquid chromatographymicrowave assisted extractionplumierideA simple and efficient microwave-assisted extraction process has been developed in order to extract plumieride from Allamanda cathartica flowers. The extracts have been obtained through microwave-assisted extraction (MAE) process with ethanol and ethyl acetate at different time, power and temperatures. Static maceration at room temperature with ethanol and ethyl acetate was obtained in order to compare the efficiency of extraction. HPLC method was validated to quantify plumieride in the extracts. The analyzed parameters: linearity (R2 = 0.999), precision (CV 3.3%), recovery (98%), specificity (97%), limit of detection (1 µg mL-1), and limit of quantification (2 µg mL-1) were satisfactory. The yield of plumieride reached 43% in the extracts under the optimal MAE conditions (10 min, 300W). Plumieride recoveries by conventional extraction method were 12% with ethanol and 22% with ethyl acetate. Time and power parameters on plumieride extraction yield was determined by applying a factorial design and surface plots. Ethanol was the best extractor solvent and it was possible to obtain high contents (52 mg g-1 of dry flowers) at optimized conditions. It can be concluded that MAE process has actual advantages over the conventional extraction method in terms of shorter time and higher efficiency to recover plumieride from A. cathartica flowers.Sociedade Brasileira de Química2018-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422018000100036Química Nova v.41 n.1 2018reponame:Química Nova (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.21577/0100-4042.20170153info:eu-repo/semantics/openAccessBonomini,Tiago J.Góes,Jaqueline A.Machado,Marina da S.Silva,Ruth M. L. daMalheiros,Angelaeng2018-02-16T00:00:00Zoai:scielo:S0100-40422018000100036Revistahttps://www.scielo.br/j/qn/ONGhttps://old.scielo.br/oai/scielo-oai.phpquimicanova@sbq.org.br1678-70640100-4042opendoar:2018-02-16T00:00Química Nova (Online) - Sociedade Brasileira de Química (SBQ)false
dc.title.none.fl_str_mv DEVELOPMENT AND OPTIMIZATION OF A MICROWAVE-ASSISTED EXTRACTION OF PLUMIERIDE FROM Allamanda cathartica L. FLOWERS
title DEVELOPMENT AND OPTIMIZATION OF A MICROWAVE-ASSISTED EXTRACTION OF PLUMIERIDE FROM Allamanda cathartica L. FLOWERS
spellingShingle DEVELOPMENT AND OPTIMIZATION OF A MICROWAVE-ASSISTED EXTRACTION OF PLUMIERIDE FROM Allamanda cathartica L. FLOWERS
Bonomini,Tiago J.
Allamanda cathartica
high performance liquid chromatography
microwave assisted extraction
plumieride
title_short DEVELOPMENT AND OPTIMIZATION OF A MICROWAVE-ASSISTED EXTRACTION OF PLUMIERIDE FROM Allamanda cathartica L. FLOWERS
title_full DEVELOPMENT AND OPTIMIZATION OF A MICROWAVE-ASSISTED EXTRACTION OF PLUMIERIDE FROM Allamanda cathartica L. FLOWERS
title_fullStr DEVELOPMENT AND OPTIMIZATION OF A MICROWAVE-ASSISTED EXTRACTION OF PLUMIERIDE FROM Allamanda cathartica L. FLOWERS
title_full_unstemmed DEVELOPMENT AND OPTIMIZATION OF A MICROWAVE-ASSISTED EXTRACTION OF PLUMIERIDE FROM Allamanda cathartica L. FLOWERS
title_sort DEVELOPMENT AND OPTIMIZATION OF A MICROWAVE-ASSISTED EXTRACTION OF PLUMIERIDE FROM Allamanda cathartica L. FLOWERS
author Bonomini,Tiago J.
author_facet Bonomini,Tiago J.
Góes,Jaqueline A.
Machado,Marina da S.
Silva,Ruth M. L. da
Malheiros,Angela
author_role author
author2 Góes,Jaqueline A.
Machado,Marina da S.
Silva,Ruth M. L. da
Malheiros,Angela
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Bonomini,Tiago J.
Góes,Jaqueline A.
Machado,Marina da S.
Silva,Ruth M. L. da
Malheiros,Angela
dc.subject.por.fl_str_mv Allamanda cathartica
high performance liquid chromatography
microwave assisted extraction
plumieride
topic Allamanda cathartica
high performance liquid chromatography
microwave assisted extraction
plumieride
description A simple and efficient microwave-assisted extraction process has been developed in order to extract plumieride from Allamanda cathartica flowers. The extracts have been obtained through microwave-assisted extraction (MAE) process with ethanol and ethyl acetate at different time, power and temperatures. Static maceration at room temperature with ethanol and ethyl acetate was obtained in order to compare the efficiency of extraction. HPLC method was validated to quantify plumieride in the extracts. The analyzed parameters: linearity (R2 = 0.999), precision (CV 3.3%), recovery (98%), specificity (97%), limit of detection (1 µg mL-1), and limit of quantification (2 µg mL-1) were satisfactory. The yield of plumieride reached 43% in the extracts under the optimal MAE conditions (10 min, 300W). Plumieride recoveries by conventional extraction method were 12% with ethanol and 22% with ethyl acetate. Time and power parameters on plumieride extraction yield was determined by applying a factorial design and surface plots. Ethanol was the best extractor solvent and it was possible to obtain high contents (52 mg g-1 of dry flowers) at optimized conditions. It can be concluded that MAE process has actual advantages over the conventional extraction method in terms of shorter time and higher efficiency to recover plumieride from A. cathartica flowers.
publishDate 2018
dc.date.none.fl_str_mv 2018-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
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dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422018000100036
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422018000100036
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.21577/0100-4042.20170153
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Química
publisher.none.fl_str_mv Sociedade Brasileira de Química
dc.source.none.fl_str_mv Química Nova v.41 n.1 2018
reponame:Química Nova (Online)
instname:Sociedade Brasileira de Química (SBQ)
instacron:SBQ
instname_str Sociedade Brasileira de Química (SBQ)
instacron_str SBQ
institution SBQ
reponame_str Química Nova (Online)
collection Química Nova (Online)
repository.name.fl_str_mv Química Nova (Online) - Sociedade Brasileira de Química (SBQ)
repository.mail.fl_str_mv quimicanova@sbq.org.br
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