Development and validation of a RP-HPLC method to determine the xanthyletin content in biodegradable polymeric nanoparticles

Detalhes bibliográficos
Autor(a) principal: Cazal,Cristiane de Melo
Data de Publicação: 2014
Outros Autores: Forim,Moacir Rossi, Silva,Maria Fátima G. Fernandes da, Vieira,Paulo Cezar, Fernandes,João Batista
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Química Nova (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422014000700007
Resumo: Xanthyletin is used as an inhibitor of the symbiotic fungus (Leucoagaricus gongylophorus) of the leaf-cutting ant (Atta sexdens rubropilosa), one of the most significant agricultural plague insects. The incorporation of this compound into nanoparticles is a promising approach to effectively control leaf-cutting ants. This study presents the development and validation of a specific analytical method using high-performance liquid chromatography (HPLC) for quantification of the xanthyletin content in biodegradable polymeric nanoparticles. The analytical methodology developed was specific, linear, accurate, precise, and robust. The absolute recovery of xanthyletin in colloidal suspensions was nearly 100%. The HPLC method proved reliable for the quantification of xanthyletin content in nanoparticle formulations.
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spelling Development and validation of a RP-HPLC method to determine the xanthyletin content in biodegradable polymeric nanoparticlesxanthyletinHPLC-UVnanoparticlesXanthyletin is used as an inhibitor of the symbiotic fungus (Leucoagaricus gongylophorus) of the leaf-cutting ant (Atta sexdens rubropilosa), one of the most significant agricultural plague insects. The incorporation of this compound into nanoparticles is a promising approach to effectively control leaf-cutting ants. This study presents the development and validation of a specific analytical method using high-performance liquid chromatography (HPLC) for quantification of the xanthyletin content in biodegradable polymeric nanoparticles. The analytical methodology developed was specific, linear, accurate, precise, and robust. The absolute recovery of xanthyletin in colloidal suspensions was nearly 100%. The HPLC method proved reliable for the quantification of xanthyletin content in nanoparticle formulations.Sociedade Brasileira de Química2014-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422014000700007Química Nova v.37 n.7 2014reponame:Química Nova (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.5935/0100-4042.20140204info:eu-repo/semantics/openAccessCazal,Cristiane de MeloForim,Moacir RossiSilva,Maria Fátima G. Fernandes daVieira,Paulo CezarFernandes,João Batistaeng2014-08-26T00:00:00Zoai:scielo:S0100-40422014000700007Revistahttps://www.scielo.br/j/qn/ONGhttps://old.scielo.br/oai/scielo-oai.phpquimicanova@sbq.org.br1678-70640100-4042opendoar:2014-08-26T00:00Química Nova (Online) - Sociedade Brasileira de Química (SBQ)false
dc.title.none.fl_str_mv Development and validation of a RP-HPLC method to determine the xanthyletin content in biodegradable polymeric nanoparticles
title Development and validation of a RP-HPLC method to determine the xanthyletin content in biodegradable polymeric nanoparticles
spellingShingle Development and validation of a RP-HPLC method to determine the xanthyletin content in biodegradable polymeric nanoparticles
Cazal,Cristiane de Melo
xanthyletin
HPLC-UV
nanoparticles
title_short Development and validation of a RP-HPLC method to determine the xanthyletin content in biodegradable polymeric nanoparticles
title_full Development and validation of a RP-HPLC method to determine the xanthyletin content in biodegradable polymeric nanoparticles
title_fullStr Development and validation of a RP-HPLC method to determine the xanthyletin content in biodegradable polymeric nanoparticles
title_full_unstemmed Development and validation of a RP-HPLC method to determine the xanthyletin content in biodegradable polymeric nanoparticles
title_sort Development and validation of a RP-HPLC method to determine the xanthyletin content in biodegradable polymeric nanoparticles
author Cazal,Cristiane de Melo
author_facet Cazal,Cristiane de Melo
Forim,Moacir Rossi
Silva,Maria Fátima G. Fernandes da
Vieira,Paulo Cezar
Fernandes,João Batista
author_role author
author2 Forim,Moacir Rossi
Silva,Maria Fátima G. Fernandes da
Vieira,Paulo Cezar
Fernandes,João Batista
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Cazal,Cristiane de Melo
Forim,Moacir Rossi
Silva,Maria Fátima G. Fernandes da
Vieira,Paulo Cezar
Fernandes,João Batista
dc.subject.por.fl_str_mv xanthyletin
HPLC-UV
nanoparticles
topic xanthyletin
HPLC-UV
nanoparticles
description Xanthyletin is used as an inhibitor of the symbiotic fungus (Leucoagaricus gongylophorus) of the leaf-cutting ant (Atta sexdens rubropilosa), one of the most significant agricultural plague insects. The incorporation of this compound into nanoparticles is a promising approach to effectively control leaf-cutting ants. This study presents the development and validation of a specific analytical method using high-performance liquid chromatography (HPLC) for quantification of the xanthyletin content in biodegradable polymeric nanoparticles. The analytical methodology developed was specific, linear, accurate, precise, and robust. The absolute recovery of xanthyletin in colloidal suspensions was nearly 100%. The HPLC method proved reliable for the quantification of xanthyletin content in nanoparticle formulations.
publishDate 2014
dc.date.none.fl_str_mv 2014-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422014000700007
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422014000700007
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.5935/0100-4042.20140204
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Química
publisher.none.fl_str_mv Sociedade Brasileira de Química
dc.source.none.fl_str_mv Química Nova v.37 n.7 2014
reponame:Química Nova (Online)
instname:Sociedade Brasileira de Química (SBQ)
instacron:SBQ
instname_str Sociedade Brasileira de Química (SBQ)
instacron_str SBQ
institution SBQ
reponame_str Química Nova (Online)
collection Química Nova (Online)
repository.name.fl_str_mv Química Nova (Online) - Sociedade Brasileira de Química (SBQ)
repository.mail.fl_str_mv quimicanova@sbq.org.br
_version_ 1750318115952001024

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