ÁLCOOL EM GEL PARA ASSEPSIA DAS MÃOS – FORMULAÇÃO ADEQUADA E EFICIÊNCIA GARANTIDA EM MEIO À PANDEMIA DA COVID-19
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Química Nova (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422022000300324 |
Resumo: | The use of hand antiseptics became widespread as a routine in the fight against COVID-19. In the market, the availability and purchase of substandard antiseptics create a permanent concern with safety, even after a pandemic. Therefore, the development of easy-to-deploy analytical methods for the quality control of alcohol-based hand antiseptics is needed. In this work, to determine the ethanol content in alcohol gel the use of refractometry and alcohol oxidation method by dichromate accompanied by UV-Vis spectroscopy were applied. The results indicated that 19 brands (out of the 70 evaluated) (27.1%) had levels of ethyl alcohol below the recommended level (68.25%), therefore, they are ineffective for hand asepsis. For the quality control of hand antiseptics, refractometry and the oxidation-reduction reaction are complementary analytical methodologies. As a quick, inexpensive screening method, refractometry provides a more suitable technique. However, the interference of emollients may affect the accuracy of the ethanol content determination. Therefore, applying the ethanol oxidation method coupled with electronic spectroscopy offers a simple and broadly accessible method to confirm the ethanol content in alcohol-based hand antiseptics. In addition to developing quality control protocols, is also described the 3.5-ton production of alcohol gel at the Federal University of Bahia. |
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ÁLCOOL EM GEL PARA ASSEPSIA DAS MÃOS – FORMULAÇÃO ADEQUADA E EFICIÊNCIA GARANTIDA EM MEIO À PANDEMIA DA COVID-19alcohol gelCOVID-19hand sanitizersdisinfectionThe use of hand antiseptics became widespread as a routine in the fight against COVID-19. In the market, the availability and purchase of substandard antiseptics create a permanent concern with safety, even after a pandemic. Therefore, the development of easy-to-deploy analytical methods for the quality control of alcohol-based hand antiseptics is needed. In this work, to determine the ethanol content in alcohol gel the use of refractometry and alcohol oxidation method by dichromate accompanied by UV-Vis spectroscopy were applied. The results indicated that 19 brands (out of the 70 evaluated) (27.1%) had levels of ethyl alcohol below the recommended level (68.25%), therefore, they are ineffective for hand asepsis. For the quality control of hand antiseptics, refractometry and the oxidation-reduction reaction are complementary analytical methodologies. As a quick, inexpensive screening method, refractometry provides a more suitable technique. However, the interference of emollients may affect the accuracy of the ethanol content determination. Therefore, applying the ethanol oxidation method coupled with electronic spectroscopy offers a simple and broadly accessible method to confirm the ethanol content in alcohol-based hand antiseptics. In addition to developing quality control protocols, is also described the 3.5-ton production of alcohol gel at the Federal University of Bahia.Sociedade Brasileira de Química2022-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422022000300324Química Nova v.45 n.3 2022reponame:Química Nova (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.21577/0100-4042.20170831info:eu-repo/semantics/openAccessFerreira,Kleber QueirozRigoli,Isabel C.Silva,Marcus V. S. daEspeleta,Alexandre de FreitasRocha,Zênis Novais dapor2022-05-16T00:00:00Zoai:scielo:S0100-40422022000300324Revistahttps://www.scielo.br/j/qn/ONGhttps://old.scielo.br/oai/scielo-oai.phpquimicanova@sbq.org.br1678-70640100-4042opendoar:2022-05-16T00:00Química Nova (Online) - Sociedade Brasileira de Química (SBQ)false |
dc.title.none.fl_str_mv |
ÁLCOOL EM GEL PARA ASSEPSIA DAS MÃOS – FORMULAÇÃO ADEQUADA E EFICIÊNCIA GARANTIDA EM MEIO À PANDEMIA DA COVID-19 |
title |
ÁLCOOL EM GEL PARA ASSEPSIA DAS MÃOS – FORMULAÇÃO ADEQUADA E EFICIÊNCIA GARANTIDA EM MEIO À PANDEMIA DA COVID-19 |
spellingShingle |
ÁLCOOL EM GEL PARA ASSEPSIA DAS MÃOS – FORMULAÇÃO ADEQUADA E EFICIÊNCIA GARANTIDA EM MEIO À PANDEMIA DA COVID-19 Ferreira,Kleber Queiroz alcohol gel COVID-19 hand sanitizers disinfection |
title_short |
ÁLCOOL EM GEL PARA ASSEPSIA DAS MÃOS – FORMULAÇÃO ADEQUADA E EFICIÊNCIA GARANTIDA EM MEIO À PANDEMIA DA COVID-19 |
title_full |
ÁLCOOL EM GEL PARA ASSEPSIA DAS MÃOS – FORMULAÇÃO ADEQUADA E EFICIÊNCIA GARANTIDA EM MEIO À PANDEMIA DA COVID-19 |
title_fullStr |
ÁLCOOL EM GEL PARA ASSEPSIA DAS MÃOS – FORMULAÇÃO ADEQUADA E EFICIÊNCIA GARANTIDA EM MEIO À PANDEMIA DA COVID-19 |
title_full_unstemmed |
ÁLCOOL EM GEL PARA ASSEPSIA DAS MÃOS – FORMULAÇÃO ADEQUADA E EFICIÊNCIA GARANTIDA EM MEIO À PANDEMIA DA COVID-19 |
title_sort |
ÁLCOOL EM GEL PARA ASSEPSIA DAS MÃOS – FORMULAÇÃO ADEQUADA E EFICIÊNCIA GARANTIDA EM MEIO À PANDEMIA DA COVID-19 |
author |
Ferreira,Kleber Queiroz |
author_facet |
Ferreira,Kleber Queiroz Rigoli,Isabel C. Silva,Marcus V. S. da Espeleta,Alexandre de Freitas Rocha,Zênis Novais da |
author_role |
author |
author2 |
Rigoli,Isabel C. Silva,Marcus V. S. da Espeleta,Alexandre de Freitas Rocha,Zênis Novais da |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Ferreira,Kleber Queiroz Rigoli,Isabel C. Silva,Marcus V. S. da Espeleta,Alexandre de Freitas Rocha,Zênis Novais da |
dc.subject.por.fl_str_mv |
alcohol gel COVID-19 hand sanitizers disinfection |
topic |
alcohol gel COVID-19 hand sanitizers disinfection |
description |
The use of hand antiseptics became widespread as a routine in the fight against COVID-19. In the market, the availability and purchase of substandard antiseptics create a permanent concern with safety, even after a pandemic. Therefore, the development of easy-to-deploy analytical methods for the quality control of alcohol-based hand antiseptics is needed. In this work, to determine the ethanol content in alcohol gel the use of refractometry and alcohol oxidation method by dichromate accompanied by UV-Vis spectroscopy were applied. The results indicated that 19 brands (out of the 70 evaluated) (27.1%) had levels of ethyl alcohol below the recommended level (68.25%), therefore, they are ineffective for hand asepsis. For the quality control of hand antiseptics, refractometry and the oxidation-reduction reaction are complementary analytical methodologies. As a quick, inexpensive screening method, refractometry provides a more suitable technique. However, the interference of emollients may affect the accuracy of the ethanol content determination. Therefore, applying the ethanol oxidation method coupled with electronic spectroscopy offers a simple and broadly accessible method to confirm the ethanol content in alcohol-based hand antiseptics. In addition to developing quality control protocols, is also described the 3.5-ton production of alcohol gel at the Federal University of Bahia. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422022000300324 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422022000300324 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
10.21577/0100-4042.20170831 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Química |
publisher.none.fl_str_mv |
Sociedade Brasileira de Química |
dc.source.none.fl_str_mv |
Química Nova v.45 n.3 2022 reponame:Química Nova (Online) instname:Sociedade Brasileira de Química (SBQ) instacron:SBQ |
instname_str |
Sociedade Brasileira de Química (SBQ) |
instacron_str |
SBQ |
institution |
SBQ |
reponame_str |
Química Nova (Online) |
collection |
Química Nova (Online) |
repository.name.fl_str_mv |
Química Nova (Online) - Sociedade Brasileira de Química (SBQ) |
repository.mail.fl_str_mv |
quimicanova@sbq.org.br |
_version_ |
1750318121834512384 |