Agentes antiasmáticos modernos: antagonistas de receptores de leucotrienos cisteínicos

Detalhes bibliográficos
Autor(a) principal: Lima,Lídia Moreira
Data de Publicação: 2002
Outros Autores: Fraga,Carlos Alberto Manssour, Barreiro,Eliezer J.
Tipo de documento: Artigo
Idioma: por
Título da fonte: Química Nova (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422002000500019
Resumo: In the early 1990s numerous clinical trials with antileukotriene drugs confirmed the hypothesis that cysteinyl leukotrienes are important bronchoconstrictor agents in asthma. Newly released"antiasthmatic medications include antileukotriene agents which function either by blocking the interaction of leukotrienes with receptors or by inhibiting leukotriene synthesis. Representatives of cysteinyl leukotriene receptors antagonists are zafirlukast (7), montelukast (8) and pranlukast (9). The bronchodilator efficacy and antiinflammatory property of antileukotriene drugs provided the main impetus behind their introduction as the first novel class of asthma therapy in more than 20 years.
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spelling Agentes antiasmáticos modernos: antagonistas de receptores de leucotrienos cisteínicosantileukotrienesantiasthmatic drugsleukotrieneIn the early 1990s numerous clinical trials with antileukotriene drugs confirmed the hypothesis that cysteinyl leukotrienes are important bronchoconstrictor agents in asthma. Newly released"antiasthmatic medications include antileukotriene agents which function either by blocking the interaction of leukotrienes with receptors or by inhibiting leukotriene synthesis. Representatives of cysteinyl leukotriene receptors antagonists are zafirlukast (7), montelukast (8) and pranlukast (9). The bronchodilator efficacy and antiinflammatory property of antileukotriene drugs provided the main impetus behind their introduction as the first novel class of asthma therapy in more than 20 years.Sociedade Brasileira de Química2002-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422002000500019Química Nova v.25 n.5 2002reponame:Química Nova (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.1590/S0100-40422002000500019info:eu-repo/semantics/openAccessLima,Lídia MoreiraFraga,Carlos Alberto ManssourBarreiro,Eliezer J.por2002-11-13T00:00:00Zoai:scielo:S0100-40422002000500019Revistahttps://www.scielo.br/j/qn/ONGhttps://old.scielo.br/oai/scielo-oai.phpquimicanova@sbq.org.br1678-70640100-4042opendoar:2002-11-13T00:00Química Nova (Online) - Sociedade Brasileira de Química (SBQ)false
dc.title.none.fl_str_mv Agentes antiasmáticos modernos: antagonistas de receptores de leucotrienos cisteínicos
title Agentes antiasmáticos modernos: antagonistas de receptores de leucotrienos cisteínicos
spellingShingle Agentes antiasmáticos modernos: antagonistas de receptores de leucotrienos cisteínicos
Lima,Lídia Moreira
antileukotrienes
antiasthmatic drugs
leukotriene
title_short Agentes antiasmáticos modernos: antagonistas de receptores de leucotrienos cisteínicos
title_full Agentes antiasmáticos modernos: antagonistas de receptores de leucotrienos cisteínicos
title_fullStr Agentes antiasmáticos modernos: antagonistas de receptores de leucotrienos cisteínicos
title_full_unstemmed Agentes antiasmáticos modernos: antagonistas de receptores de leucotrienos cisteínicos
title_sort Agentes antiasmáticos modernos: antagonistas de receptores de leucotrienos cisteínicos
author Lima,Lídia Moreira
author_facet Lima,Lídia Moreira
Fraga,Carlos Alberto Manssour
Barreiro,Eliezer J.
author_role author
author2 Fraga,Carlos Alberto Manssour
Barreiro,Eliezer J.
author2_role author
author
dc.contributor.author.fl_str_mv Lima,Lídia Moreira
Fraga,Carlos Alberto Manssour
Barreiro,Eliezer J.
dc.subject.por.fl_str_mv antileukotrienes
antiasthmatic drugs
leukotriene
topic antileukotrienes
antiasthmatic drugs
leukotriene
description In the early 1990s numerous clinical trials with antileukotriene drugs confirmed the hypothesis that cysteinyl leukotrienes are important bronchoconstrictor agents in asthma. Newly released"antiasthmatic medications include antileukotriene agents which function either by blocking the interaction of leukotrienes with receptors or by inhibiting leukotriene synthesis. Representatives of cysteinyl leukotriene receptors antagonists are zafirlukast (7), montelukast (8) and pranlukast (9). The bronchodilator efficacy and antiinflammatory property of antileukotriene drugs provided the main impetus behind their introduction as the first novel class of asthma therapy in more than 20 years.
publishDate 2002
dc.date.none.fl_str_mv 2002-09-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422002000500019
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422002000500019
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv 10.1590/S0100-40422002000500019
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Química
publisher.none.fl_str_mv Sociedade Brasileira de Química
dc.source.none.fl_str_mv Química Nova v.25 n.5 2002
reponame:Química Nova (Online)
instname:Sociedade Brasileira de Química (SBQ)
instacron:SBQ
instname_str Sociedade Brasileira de Química (SBQ)
instacron_str SBQ
institution SBQ
reponame_str Química Nova (Online)
collection Química Nova (Online)
repository.name.fl_str_mv Química Nova (Online) - Sociedade Brasileira de Química (SBQ)
repository.mail.fl_str_mv quimicanova@sbq.org.br
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