Flavonoides e terpenoides de Croton muscicarpa (Euphorbiaceae)

• Autor(a) principal: Barreto,Milena B.
• Data de Publicação: 2013
• Outros Autores: Gomes,Clêrton L., Freitas,João Vito B. de, Pinto,Francisco das Chagas L., Silveira,Edilberto R., Gramosa,Nilce V., Torres,Daniela S. Carneiro
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Química Nova (Online)
• Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422013000500011
• topic: Croton muscicarpa; Euphorbiaceae; cyperene derivative

A new sesquiterpene and twelve known compounds comprising eight flavonoids and four terpenoids, were isolated from the leaves, stems, roots and exudate of Croton muscicarpa Müll. Arg.. Their structures were identified as the terpenoids 6α-methoxy-cyperene, dammaradienol, squalene, acetyl aleuritolic acid and spathulenol, and as the flavonoids retusin, 3,7,4'-trimethoxy kaempferol, ombuine, pachipodol, kaempferol, casticin, 5-hydroxy-3,6,7,4'-tetramethoxyflavone and artemetin. All isolated compounds were characterized based on IR, MS, ¹H and 13C NMR, including 2D analyses (COSY, HSQC, HMBC, NOESY) and comparison with data from the literature.