Agentes dopaminérgicos e o tratamento da disfunção erétil

Detalhes bibliográficos
Autor(a) principal: Neves,Gilda
Data de Publicação: 2004
Outros Autores: Rates,Stela M. K., Fraga,Carlos A. M., Barreiro,Eliezer J.
Tipo de documento: Artigo
Idioma: por
Título da fonte: Química Nova (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422004000600020
Resumo: The understanding of the scientific basis of the erectile function expanded rapidly the range of therapies for treating erectile dysfunction in recent years. This article reviews the role of dopamine on the erection mechanisms and its importance for new pro-erectile drug design. The ability of dopaminergic agents to elicit penile erection has been described since 1975 and successively confirmed by numerous studies. The development of apomorphine SL (dopaminergic non selective agonist) to enhance erectile function represents a new pharmacological approach to the management of erectile dysfunction using CNS drugs. The search for selective D4 dopaminergic agents is being explored by some research groups and pharmaceutical companies.
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spelling Agentes dopaminérgicos e o tratamento da disfunção erétilerectile dysfunctiondopaminergic agentsapomorphineThe understanding of the scientific basis of the erectile function expanded rapidly the range of therapies for treating erectile dysfunction in recent years. This article reviews the role of dopamine on the erection mechanisms and its importance for new pro-erectile drug design. The ability of dopaminergic agents to elicit penile erection has been described since 1975 and successively confirmed by numerous studies. The development of apomorphine SL (dopaminergic non selective agonist) to enhance erectile function represents a new pharmacological approach to the management of erectile dysfunction using CNS drugs. The search for selective D4 dopaminergic agents is being explored by some research groups and pharmaceutical companies.Sociedade Brasileira de Química2004-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422004000600020Química Nova v.27 n.6 2004reponame:Química Nova (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.1590/S0100-40422004000600020info:eu-repo/semantics/openAccessNeves,GildaRates,Stela M. K.Fraga,Carlos A. M.Barreiro,Eliezer J.por2004-11-30T00:00:00Zoai:scielo:S0100-40422004000600020Revistahttps://www.scielo.br/j/qn/ONGhttps://old.scielo.br/oai/scielo-oai.phpquimicanova@sbq.org.br1678-70640100-4042opendoar:2004-11-30T00:00Química Nova (Online) - Sociedade Brasileira de Química (SBQ)false
dc.title.none.fl_str_mv Agentes dopaminérgicos e o tratamento da disfunção erétil
title Agentes dopaminérgicos e o tratamento da disfunção erétil
spellingShingle Agentes dopaminérgicos e o tratamento da disfunção erétil
Neves,Gilda
erectile dysfunction
dopaminergic agents
apomorphine
title_short Agentes dopaminérgicos e o tratamento da disfunção erétil
title_full Agentes dopaminérgicos e o tratamento da disfunção erétil
title_fullStr Agentes dopaminérgicos e o tratamento da disfunção erétil
title_full_unstemmed Agentes dopaminérgicos e o tratamento da disfunção erétil
title_sort Agentes dopaminérgicos e o tratamento da disfunção erétil
author Neves,Gilda
author_facet Neves,Gilda
Rates,Stela M. K.
Fraga,Carlos A. M.
Barreiro,Eliezer J.
author_role author
author2 Rates,Stela M. K.
Fraga,Carlos A. M.
Barreiro,Eliezer J.
author2_role author
author
author
dc.contributor.author.fl_str_mv Neves,Gilda
Rates,Stela M. K.
Fraga,Carlos A. M.
Barreiro,Eliezer J.
dc.subject.por.fl_str_mv erectile dysfunction
dopaminergic agents
apomorphine
topic erectile dysfunction
dopaminergic agents
apomorphine
description The understanding of the scientific basis of the erectile function expanded rapidly the range of therapies for treating erectile dysfunction in recent years. This article reviews the role of dopamine on the erection mechanisms and its importance for new pro-erectile drug design. The ability of dopaminergic agents to elicit penile erection has been described since 1975 and successively confirmed by numerous studies. The development of apomorphine SL (dopaminergic non selective agonist) to enhance erectile function represents a new pharmacological approach to the management of erectile dysfunction using CNS drugs. The search for selective D4 dopaminergic agents is being explored by some research groups and pharmaceutical companies.
publishDate 2004
dc.date.none.fl_str_mv 2004-12-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422004000600020
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422004000600020
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv 10.1590/S0100-40422004000600020
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Química
publisher.none.fl_str_mv Sociedade Brasileira de Química
dc.source.none.fl_str_mv Química Nova v.27 n.6 2004
reponame:Química Nova (Online)
instname:Sociedade Brasileira de Química (SBQ)
instacron:SBQ
instname_str Sociedade Brasileira de Química (SBQ)
instacron_str SBQ
institution SBQ
reponame_str Química Nova (Online)
collection Química Nova (Online)
repository.name.fl_str_mv Química Nova (Online) - Sociedade Brasileira de Química (SBQ)
repository.mail.fl_str_mv quimicanova@sbq.org.br
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