Hemoglobina extracelular gigante de Glossoscolex paulistus: um extraordinário sistema supramolecular hemoproteico

Detalhes bibliográficos
Autor(a) principal: Moreira,Leonardo Marmo
Data de Publicação: 2011
Outros Autores: Moraes,Pedro Claudio Guaranho de, Mendonça,José Paulo Rodrigues Furtado de, Guimarães,Luciana, Lyon,Juliana Pereira, Aimbire,Flávio, Poli,Alessandra Lima, Imasato,Hidetake
Tipo de documento: Artigo
Idioma: por
Título da fonte: Química Nova (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422011000100023
Resumo: Giant extracellular hemoglobins are considered the summit of complexity in systems that carry oxygen, constituting an extraordinary model system to the study of hemoproteins. This class includes the hemoglobin of the annelid Glossoscolex paulistus that presents high cooperativity, great oligomeric and redox stabilities and ability of oligomeric reassociation. These properties have motivated evaluations about its utilization as prototype of artificial blood and biosensor. Kinetic studies involving autoxidation and detailed spectroscopic characterizations of its ferrous and ferric species have propitiated information about the structure-activity relationship of this macromolecule. The present review analyzes several biochemical issues, evaluating the state-of-art of this subject.
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spelling Hemoglobina extracelular gigante de Glossoscolex paulistus: um extraordinário sistema supramolecular hemoproteicohemoglobinligand exchangeautoxidationGiant extracellular hemoglobins are considered the summit of complexity in systems that carry oxygen, constituting an extraordinary model system to the study of hemoproteins. This class includes the hemoglobin of the annelid Glossoscolex paulistus that presents high cooperativity, great oligomeric and redox stabilities and ability of oligomeric reassociation. These properties have motivated evaluations about its utilization as prototype of artificial blood and biosensor. Kinetic studies involving autoxidation and detailed spectroscopic characterizations of its ferrous and ferric species have propitiated information about the structure-activity relationship of this macromolecule. The present review analyzes several biochemical issues, evaluating the state-of-art of this subject.Sociedade Brasileira de Química2011-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422011000100023Química Nova v.34 n.1 2011reponame:Química Nova (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.1590/S0100-40422011000100023info:eu-repo/semantics/openAccessMoreira,Leonardo MarmoMoraes,Pedro Claudio Guaranho deMendonça,José Paulo Rodrigues Furtado deGuimarães,LucianaLyon,Juliana PereiraAimbire,FlávioPoli,Alessandra LimaImasato,Hidetakepor2011-02-10T00:00:00Zoai:scielo:S0100-40422011000100023Revistahttps://www.scielo.br/j/qn/ONGhttps://old.scielo.br/oai/scielo-oai.phpquimicanova@sbq.org.br1678-70640100-4042opendoar:2011-02-10T00:00Química Nova (Online) - Sociedade Brasileira de Química (SBQ)false
dc.title.none.fl_str_mv Hemoglobina extracelular gigante de Glossoscolex paulistus: um extraordinário sistema supramolecular hemoproteico
title Hemoglobina extracelular gigante de Glossoscolex paulistus: um extraordinário sistema supramolecular hemoproteico
spellingShingle Hemoglobina extracelular gigante de Glossoscolex paulistus: um extraordinário sistema supramolecular hemoproteico
Moreira,Leonardo Marmo
hemoglobin
ligand exchange
autoxidation
title_short Hemoglobina extracelular gigante de Glossoscolex paulistus: um extraordinário sistema supramolecular hemoproteico
title_full Hemoglobina extracelular gigante de Glossoscolex paulistus: um extraordinário sistema supramolecular hemoproteico
title_fullStr Hemoglobina extracelular gigante de Glossoscolex paulistus: um extraordinário sistema supramolecular hemoproteico
title_full_unstemmed Hemoglobina extracelular gigante de Glossoscolex paulistus: um extraordinário sistema supramolecular hemoproteico
title_sort Hemoglobina extracelular gigante de Glossoscolex paulistus: um extraordinário sistema supramolecular hemoproteico
author Moreira,Leonardo Marmo
author_facet Moreira,Leonardo Marmo
Moraes,Pedro Claudio Guaranho de
Mendonça,José Paulo Rodrigues Furtado de
Guimarães,Luciana
Lyon,Juliana Pereira
Aimbire,Flávio
Poli,Alessandra Lima
Imasato,Hidetake
author_role author
author2 Moraes,Pedro Claudio Guaranho de
Mendonça,José Paulo Rodrigues Furtado de
Guimarães,Luciana
Lyon,Juliana Pereira
Aimbire,Flávio
Poli,Alessandra Lima
Imasato,Hidetake
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Moreira,Leonardo Marmo
Moraes,Pedro Claudio Guaranho de
Mendonça,José Paulo Rodrigues Furtado de
Guimarães,Luciana
Lyon,Juliana Pereira
Aimbire,Flávio
Poli,Alessandra Lima
Imasato,Hidetake
dc.subject.por.fl_str_mv hemoglobin
ligand exchange
autoxidation
topic hemoglobin
ligand exchange
autoxidation
description Giant extracellular hemoglobins are considered the summit of complexity in systems that carry oxygen, constituting an extraordinary model system to the study of hemoproteins. This class includes the hemoglobin of the annelid Glossoscolex paulistus that presents high cooperativity, great oligomeric and redox stabilities and ability of oligomeric reassociation. These properties have motivated evaluations about its utilization as prototype of artificial blood and biosensor. Kinetic studies involving autoxidation and detailed spectroscopic characterizations of its ferrous and ferric species have propitiated information about the structure-activity relationship of this macromolecule. The present review analyzes several biochemical issues, evaluating the state-of-art of this subject.
publishDate 2011
dc.date.none.fl_str_mv 2011-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422011000100023
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422011000100023
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv 10.1590/S0100-40422011000100023
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Química
publisher.none.fl_str_mv Sociedade Brasileira de Química
dc.source.none.fl_str_mv Química Nova v.34 n.1 2011
reponame:Química Nova (Online)
instname:Sociedade Brasileira de Química (SBQ)
instacron:SBQ
instname_str Sociedade Brasileira de Química (SBQ)
instacron_str SBQ
institution SBQ
reponame_str Química Nova (Online)
collection Química Nova (Online)
repository.name.fl_str_mv Química Nova (Online) - Sociedade Brasileira de Química (SBQ)
repository.mail.fl_str_mv quimicanova@sbq.org.br
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