ATIVIDADE ANTIMICROBIANA DE QUITOSANAS E SEUS DERIVADOS: INFLUÊNCIA DAS CARACTERÍSTICAS ESTRUTURAIS
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Química Nova (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422022000600690 |
Resumo: | In recent years, there has been an increasing interest in the development of antimicrobial materials for different applications, especially in the biomedical field. In this context, chitosan is one of the most employed materials due to its highly attractive properties, such as biocompatibility, biodegradability, non-toxicity, and antimicrobial activity against gram-negative and gram-positive bacteria and fungi. In this review, we discuss the different methods used to obtain chitosan and point out how they affect the structural and chemical properties of this material, followed by a detailed discussion on how these properties influence its antimicrobial activities. Additionally, we summarize the most accepted antimicrobial mechanisms of action for chitosans. Specifically, we aim to provide a comprehensive overview on the last findings and progress reported in the literature on the factors that influence the antimicrobial activity of chitosan, e.g., polymeric average molecular weight ( M W ¯), average degree of acetylation ( D A ¯), water-soluble derivatization and sample degree of purity. The data available in the literature indicate that in addition to the structural properties, the effectiveness of such antimicrobial activity of chitosan is also dependent on the target microorganisms. This review will help researchers to better understand the mechanism of action of chitosan against microorganisms based on its structural characteristics. |
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ATIVIDADE ANTIMICROBIANA DE QUITOSANAS E SEUS DERIVADOS: INFLUÊNCIA DAS CARACTERÍSTICAS ESTRUTURAISchitosanantimicrobial mechanismssourceaverage acetylation degreemolecular weight.In recent years, there has been an increasing interest in the development of antimicrobial materials for different applications, especially in the biomedical field. In this context, chitosan is one of the most employed materials due to its highly attractive properties, such as biocompatibility, biodegradability, non-toxicity, and antimicrobial activity against gram-negative and gram-positive bacteria and fungi. In this review, we discuss the different methods used to obtain chitosan and point out how they affect the structural and chemical properties of this material, followed by a detailed discussion on how these properties influence its antimicrobial activities. Additionally, we summarize the most accepted antimicrobial mechanisms of action for chitosans. Specifically, we aim to provide a comprehensive overview on the last findings and progress reported in the literature on the factors that influence the antimicrobial activity of chitosan, e.g., polymeric average molecular weight ( M W ¯), average degree of acetylation ( D A ¯), water-soluble derivatization and sample degree of purity. The data available in the literature indicate that in addition to the structural properties, the effectiveness of such antimicrobial activity of chitosan is also dependent on the target microorganisms. This review will help researchers to better understand the mechanism of action of chitosan against microorganisms based on its structural characteristics.Sociedade Brasileira de Química2022-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422022000600690Química Nova v.45 n.6 2022reponame:Química Nova (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.21577/0100-4042.20170867info:eu-repo/semantics/openAccessMacedo,Juliana B.Sanfelice,Rafaela C.Mercante,Luiza A.Santos,Danilo Martins dosHabitzreuter,FilipeCampana-Filho,Sérgio PauloPavinatto,Adrianapor2022-08-26T00:00:00Zoai:scielo:S0100-40422022000600690Revistahttps://www.scielo.br/j/qn/ONGhttps://old.scielo.br/oai/scielo-oai.phpquimicanova@sbq.org.br1678-70640100-4042opendoar:2022-08-26T00:00Química Nova (Online) - Sociedade Brasileira de Química (SBQ)false |
dc.title.none.fl_str_mv |
ATIVIDADE ANTIMICROBIANA DE QUITOSANAS E SEUS DERIVADOS: INFLUÊNCIA DAS CARACTERÍSTICAS ESTRUTURAIS |
title |
ATIVIDADE ANTIMICROBIANA DE QUITOSANAS E SEUS DERIVADOS: INFLUÊNCIA DAS CARACTERÍSTICAS ESTRUTURAIS |
spellingShingle |
ATIVIDADE ANTIMICROBIANA DE QUITOSANAS E SEUS DERIVADOS: INFLUÊNCIA DAS CARACTERÍSTICAS ESTRUTURAIS Macedo,Juliana B. chitosan antimicrobial mechanisms source average acetylation degree molecular weight. |
title_short |
ATIVIDADE ANTIMICROBIANA DE QUITOSANAS E SEUS DERIVADOS: INFLUÊNCIA DAS CARACTERÍSTICAS ESTRUTURAIS |
title_full |
ATIVIDADE ANTIMICROBIANA DE QUITOSANAS E SEUS DERIVADOS: INFLUÊNCIA DAS CARACTERÍSTICAS ESTRUTURAIS |
title_fullStr |
ATIVIDADE ANTIMICROBIANA DE QUITOSANAS E SEUS DERIVADOS: INFLUÊNCIA DAS CARACTERÍSTICAS ESTRUTURAIS |
title_full_unstemmed |
ATIVIDADE ANTIMICROBIANA DE QUITOSANAS E SEUS DERIVADOS: INFLUÊNCIA DAS CARACTERÍSTICAS ESTRUTURAIS |
title_sort |
ATIVIDADE ANTIMICROBIANA DE QUITOSANAS E SEUS DERIVADOS: INFLUÊNCIA DAS CARACTERÍSTICAS ESTRUTURAIS |
author |
Macedo,Juliana B. |
author_facet |
Macedo,Juliana B. Sanfelice,Rafaela C. Mercante,Luiza A. Santos,Danilo Martins dos Habitzreuter,Filipe Campana-Filho,Sérgio Paulo Pavinatto,Adriana |
author_role |
author |
author2 |
Sanfelice,Rafaela C. Mercante,Luiza A. Santos,Danilo Martins dos Habitzreuter,Filipe Campana-Filho,Sérgio Paulo Pavinatto,Adriana |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Macedo,Juliana B. Sanfelice,Rafaela C. Mercante,Luiza A. Santos,Danilo Martins dos Habitzreuter,Filipe Campana-Filho,Sérgio Paulo Pavinatto,Adriana |
dc.subject.por.fl_str_mv |
chitosan antimicrobial mechanisms source average acetylation degree molecular weight. |
topic |
chitosan antimicrobial mechanisms source average acetylation degree molecular weight. |
description |
In recent years, there has been an increasing interest in the development of antimicrobial materials for different applications, especially in the biomedical field. In this context, chitosan is one of the most employed materials due to its highly attractive properties, such as biocompatibility, biodegradability, non-toxicity, and antimicrobial activity against gram-negative and gram-positive bacteria and fungi. In this review, we discuss the different methods used to obtain chitosan and point out how they affect the structural and chemical properties of this material, followed by a detailed discussion on how these properties influence its antimicrobial activities. Additionally, we summarize the most accepted antimicrobial mechanisms of action for chitosans. Specifically, we aim to provide a comprehensive overview on the last findings and progress reported in the literature on the factors that influence the antimicrobial activity of chitosan, e.g., polymeric average molecular weight ( M W ¯), average degree of acetylation ( D A ¯), water-soluble derivatization and sample degree of purity. The data available in the literature indicate that in addition to the structural properties, the effectiveness of such antimicrobial activity of chitosan is also dependent on the target microorganisms. This review will help researchers to better understand the mechanism of action of chitosan against microorganisms based on its structural characteristics. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-06-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422022000600690 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422022000600690 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
10.21577/0100-4042.20170867 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Química |
publisher.none.fl_str_mv |
Sociedade Brasileira de Química |
dc.source.none.fl_str_mv |
Química Nova v.45 n.6 2022 reponame:Química Nova (Online) instname:Sociedade Brasileira de Química (SBQ) instacron:SBQ |
instname_str |
Sociedade Brasileira de Química (SBQ) |
instacron_str |
SBQ |
institution |
SBQ |
reponame_str |
Química Nova (Online) |
collection |
Química Nova (Online) |
repository.name.fl_str_mv |
Química Nova (Online) - Sociedade Brasileira de Química (SBQ) |
repository.mail.fl_str_mv |
quimicanova@sbq.org.br |
_version_ |
1750318121893232640 |