Interação de compostos organossulfurados derivados do alho com o citocromo-c: um estudo eletroquímico

Detalhes bibliográficos
Autor(a) principal: Reina,Luisa del Carmen Barrett
Data de Publicação: 2002
Outros Autores: Montanari,Carlos Alberto, Donnici,Claudio Luis, Diógenes,Izaura Cirino Nogueira, Moreira,Ícaro de Sousa
Tipo de documento: Artigo
Idioma: por
Título da fonte: Química Nova (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422002000100002
Resumo: Organosulfur compounds present in garlic and onion have been evaluated as inhibitors of chemical carcinogenesis. Among them diallylsulfide was mainly investigated and studies demonstrated its metabolization to the corresponding sulfoxide and sulfone. In this work, we report the investigation of the interaction between the diallylsulfide and its oxidized derivatives, through cyclic voltammetry, with horse heart cytocrome-c (on a modified electrode with 4-mercaptopyridine). Our results suggest that there is a reversible interaction between cytocrome-c and diallylsulfide and diallylsulfone and an irreversible interaction with the diallylsulfoxide.
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spelling Interação de compostos organossulfurados derivados do alho com o citocromo-c: um estudo eletroquímicodiallylsulfide derivativescyclic voltammetrycytochrome-cOrganosulfur compounds present in garlic and onion have been evaluated as inhibitors of chemical carcinogenesis. Among them diallylsulfide was mainly investigated and studies demonstrated its metabolization to the corresponding sulfoxide and sulfone. In this work, we report the investigation of the interaction between the diallylsulfide and its oxidized derivatives, through cyclic voltammetry, with horse heart cytocrome-c (on a modified electrode with 4-mercaptopyridine). Our results suggest that there is a reversible interaction between cytocrome-c and diallylsulfide and diallylsulfone and an irreversible interaction with the diallylsulfoxide.Sociedade Brasileira de Química2002-02-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422002000100002Química Nova v.25 n.1 2002reponame:Química Nova (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.1590/S0100-40422002000100002info:eu-repo/semantics/openAccessReina,Luisa del Carmen BarrettMontanari,Carlos AlbertoDonnici,Claudio LuisDiógenes,Izaura Cirino NogueiraMoreira,Ícaro de Sousapor2002-07-31T00:00:00Zoai:scielo:S0100-40422002000100002Revistahttps://www.scielo.br/j/qn/ONGhttps://old.scielo.br/oai/scielo-oai.phpquimicanova@sbq.org.br1678-70640100-4042opendoar:2002-07-31T00:00Química Nova (Online) - Sociedade Brasileira de Química (SBQ)false
dc.title.none.fl_str_mv Interação de compostos organossulfurados derivados do alho com o citocromo-c: um estudo eletroquímico
title Interação de compostos organossulfurados derivados do alho com o citocromo-c: um estudo eletroquímico
spellingShingle Interação de compostos organossulfurados derivados do alho com o citocromo-c: um estudo eletroquímico
Reina,Luisa del Carmen Barrett
diallylsulfide derivatives
cyclic voltammetry
cytochrome-c
title_short Interação de compostos organossulfurados derivados do alho com o citocromo-c: um estudo eletroquímico
title_full Interação de compostos organossulfurados derivados do alho com o citocromo-c: um estudo eletroquímico
title_fullStr Interação de compostos organossulfurados derivados do alho com o citocromo-c: um estudo eletroquímico
title_full_unstemmed Interação de compostos organossulfurados derivados do alho com o citocromo-c: um estudo eletroquímico
title_sort Interação de compostos organossulfurados derivados do alho com o citocromo-c: um estudo eletroquímico
author Reina,Luisa del Carmen Barrett
author_facet Reina,Luisa del Carmen Barrett
Montanari,Carlos Alberto
Donnici,Claudio Luis
Diógenes,Izaura Cirino Nogueira
Moreira,Ícaro de Sousa
author_role author
author2 Montanari,Carlos Alberto
Donnici,Claudio Luis
Diógenes,Izaura Cirino Nogueira
Moreira,Ícaro de Sousa
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Reina,Luisa del Carmen Barrett
Montanari,Carlos Alberto
Donnici,Claudio Luis
Diógenes,Izaura Cirino Nogueira
Moreira,Ícaro de Sousa
dc.subject.por.fl_str_mv diallylsulfide derivatives
cyclic voltammetry
cytochrome-c
topic diallylsulfide derivatives
cyclic voltammetry
cytochrome-c
description Organosulfur compounds present in garlic and onion have been evaluated as inhibitors of chemical carcinogenesis. Among them diallylsulfide was mainly investigated and studies demonstrated its metabolization to the corresponding sulfoxide and sulfone. In this work, we report the investigation of the interaction between the diallylsulfide and its oxidized derivatives, through cyclic voltammetry, with horse heart cytocrome-c (on a modified electrode with 4-mercaptopyridine). Our results suggest that there is a reversible interaction between cytocrome-c and diallylsulfide and diallylsulfone and an irreversible interaction with the diallylsulfoxide.
publishDate 2002
dc.date.none.fl_str_mv 2002-02-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422002000100002
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422002000100002
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv 10.1590/S0100-40422002000100002
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Química
publisher.none.fl_str_mv Sociedade Brasileira de Química
dc.source.none.fl_str_mv Química Nova v.25 n.1 2002
reponame:Química Nova (Online)
instname:Sociedade Brasileira de Química (SBQ)
instacron:SBQ
instname_str Sociedade Brasileira de Química (SBQ)
instacron_str SBQ
institution SBQ
reponame_str Química Nova (Online)
collection Química Nova (Online)
repository.name.fl_str_mv Química Nova (Online) - Sociedade Brasileira de Química (SBQ)
repository.mail.fl_str_mv quimicanova@sbq.org.br
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