Synthesis and evaluation of octocrylene-inspired compounds for UV-filter activity

Detalhes bibliográficos
Autor(a) principal: Polonini,Hudson C.
Data de Publicação: 2014
Outros Autores: Lopes,Rosângela S., Beatriz,Adilson, Gomes,Roberto S., Silva,Adriano O., Lima,Ricardo V. de, Nunes,Gláucia. A., Brandão,Marcos Antônio F., Raposo,Nádia R. B., Lima,Dênis P. de
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Química Nova (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422014000600014
Resumo: Octocrylene (2-ethylhexyl 2-cyano-3,3-diphenyl-2-propenoate) is present in several sunscreens and is known to work synergistically with UV filters. We prepared eight octocrylene-related compounds to test their photoprotective activities by measuring diffuse transmittance. The compounds had varied photoprotection profiles, with Sun Protection Factors (SPF) ranging from 1 to 5 and UVA Protection Factors (UVAPF) ranging from 1 to 8. Compounds 4, 5, and 7 showed the best protection against UVB sunrays, while compounds 5, 6, and 7 presented the best results for protection from UVA, so compound 7 had the most balanced protection overall. Results for compounds 4, 8, and 9 are reported for the first time in the literature.
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spelling Synthesis and evaluation of octocrylene-inspired compounds for UV-filter activitysunscreensoctocrylenephotoprotective activityOctocrylene (2-ethylhexyl 2-cyano-3,3-diphenyl-2-propenoate) is present in several sunscreens and is known to work synergistically with UV filters. We prepared eight octocrylene-related compounds to test their photoprotective activities by measuring diffuse transmittance. The compounds had varied photoprotection profiles, with Sun Protection Factors (SPF) ranging from 1 to 5 and UVA Protection Factors (UVAPF) ranging from 1 to 8. Compounds 4, 5, and 7 showed the best protection against UVB sunrays, while compounds 5, 6, and 7 presented the best results for protection from UVA, so compound 7 had the most balanced protection overall. Results for compounds 4, 8, and 9 are reported for the first time in the literature.Sociedade Brasileira de Química2014-07-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422014000600014Química Nova v.37 n.6 2014reponame:Química Nova (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.5935/0100-4042.20140160info:eu-repo/semantics/openAccessPolonini,Hudson C.Lopes,Rosângela S.Beatriz,AdilsonGomes,Roberto S.Silva,Adriano O.Lima,Ricardo V. deNunes,Gláucia. A.Brandão,Marcos Antônio F.Raposo,Nádia R. B.Lima,Dênis P. deeng2014-08-01T00:00:00Zoai:scielo:S0100-40422014000600014Revistahttps://www.scielo.br/j/qn/ONGhttps://old.scielo.br/oai/scielo-oai.phpquimicanova@sbq.org.br1678-70640100-4042opendoar:2014-08-01T00:00Química Nova (Online) - Sociedade Brasileira de Química (SBQ)false
dc.title.none.fl_str_mv Synthesis and evaluation of octocrylene-inspired compounds for UV-filter activity
title Synthesis and evaluation of octocrylene-inspired compounds for UV-filter activity
spellingShingle Synthesis and evaluation of octocrylene-inspired compounds for UV-filter activity
Polonini,Hudson C.
sunscreens
octocrylene
photoprotective activity
title_short Synthesis and evaluation of octocrylene-inspired compounds for UV-filter activity
title_full Synthesis and evaluation of octocrylene-inspired compounds for UV-filter activity
title_fullStr Synthesis and evaluation of octocrylene-inspired compounds for UV-filter activity
title_full_unstemmed Synthesis and evaluation of octocrylene-inspired compounds for UV-filter activity
title_sort Synthesis and evaluation of octocrylene-inspired compounds for UV-filter activity
author Polonini,Hudson C.
author_facet Polonini,Hudson C.
Lopes,Rosângela S.
Beatriz,Adilson
Gomes,Roberto S.
Silva,Adriano O.
Lima,Ricardo V. de
Nunes,Gláucia. A.
Brandão,Marcos Antônio F.
Raposo,Nádia R. B.
Lima,Dênis P. de
author_role author
author2 Lopes,Rosângela S.
Beatriz,Adilson
Gomes,Roberto S.
Silva,Adriano O.
Lima,Ricardo V. de
Nunes,Gláucia. A.
Brandão,Marcos Antônio F.
Raposo,Nádia R. B.
Lima,Dênis P. de
author2_role author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Polonini,Hudson C.
Lopes,Rosângela S.
Beatriz,Adilson
Gomes,Roberto S.
Silva,Adriano O.
Lima,Ricardo V. de
Nunes,Gláucia. A.
Brandão,Marcos Antônio F.
Raposo,Nádia R. B.
Lima,Dênis P. de
dc.subject.por.fl_str_mv sunscreens
octocrylene
photoprotective activity
topic sunscreens
octocrylene
photoprotective activity
description Octocrylene (2-ethylhexyl 2-cyano-3,3-diphenyl-2-propenoate) is present in several sunscreens and is known to work synergistically with UV filters. We prepared eight octocrylene-related compounds to test their photoprotective activities by measuring diffuse transmittance. The compounds had varied photoprotection profiles, with Sun Protection Factors (SPF) ranging from 1 to 5 and UVA Protection Factors (UVAPF) ranging from 1 to 8. Compounds 4, 5, and 7 showed the best protection against UVB sunrays, while compounds 5, 6, and 7 presented the best results for protection from UVA, so compound 7 had the most balanced protection overall. Results for compounds 4, 8, and 9 are reported for the first time in the literature.
publishDate 2014
dc.date.none.fl_str_mv 2014-07-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422014000600014
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422014000600014
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.5935/0100-4042.20140160
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Química
publisher.none.fl_str_mv Sociedade Brasileira de Química
dc.source.none.fl_str_mv Química Nova v.37 n.6 2014
reponame:Química Nova (Online)
instname:Sociedade Brasileira de Química (SBQ)
instacron:SBQ
instname_str Sociedade Brasileira de Química (SBQ)
instacron_str SBQ
institution SBQ
reponame_str Química Nova (Online)
collection Química Nova (Online)
repository.name.fl_str_mv Química Nova (Online) - Sociedade Brasileira de Química (SBQ)
repository.mail.fl_str_mv quimicanova@sbq.org.br
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