Produtos naturais como candidatos a fármacos úteis no tratamento do Mal de Alzheimer

Detalhes bibliográficos
Autor(a) principal: Viegas Junior,Cláudio
Data de Publicação: 2004
Outros Autores: Bolzani,Vanderlan da Silva, Furlan,Maysa, Fraga,Carlos Alberto Manssour, Barreiro,Eliezer J.
Tipo de documento: Artigo
Idioma: por
Título da fonte: Química Nova (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422004000400021
Resumo: Alzheimer's disease (AD) is a progressive neurodegenerative pathology with severe economic and social impact. There is currently no cure, although cholinesterase inhibitors provide effective temporary relief of symptoms in some patients. Nowadays drug research and development are based on the cholinergic hypothesis that supports the cognition improvement by regulation of the synthesis and release of acetylcholine in the brain. There are only four commercial medicines approved for treatment of AD and natural products have played an important role in the research for new acetylcholinesterase inhibitors.
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spelling Produtos naturais como candidatos a fármacos úteis no tratamento do Mal de AlzheimerAlzheimer's diseaseacetylcholinesterasenatural productsAlzheimer's disease (AD) is a progressive neurodegenerative pathology with severe economic and social impact. There is currently no cure, although cholinesterase inhibitors provide effective temporary relief of symptoms in some patients. Nowadays drug research and development are based on the cholinergic hypothesis that supports the cognition improvement by regulation of the synthesis and release of acetylcholine in the brain. There are only four commercial medicines approved for treatment of AD and natural products have played an important role in the research for new acetylcholinesterase inhibitors.Sociedade Brasileira de Química2004-08-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422004000400021Química Nova v.27 n.4 2004reponame:Química Nova (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.1590/S0100-40422004000400021info:eu-repo/semantics/openAccessViegas Junior,CláudioBolzani,Vanderlan da SilvaFurlan,MaysaFraga,Carlos Alberto ManssourBarreiro,Eliezer J.por2004-07-31T00:00:00Zoai:scielo:S0100-40422004000400021Revistahttps://www.scielo.br/j/qn/ONGhttps://old.scielo.br/oai/scielo-oai.phpquimicanova@sbq.org.br1678-70640100-4042opendoar:2004-07-31T00:00Química Nova (Online) - Sociedade Brasileira de Química (SBQ)false
dc.title.none.fl_str_mv Produtos naturais como candidatos a fármacos úteis no tratamento do Mal de Alzheimer
title Produtos naturais como candidatos a fármacos úteis no tratamento do Mal de Alzheimer
spellingShingle Produtos naturais como candidatos a fármacos úteis no tratamento do Mal de Alzheimer
Viegas Junior,Cláudio
Alzheimer's disease
acetylcholinesterase
natural products
title_short Produtos naturais como candidatos a fármacos úteis no tratamento do Mal de Alzheimer
title_full Produtos naturais como candidatos a fármacos úteis no tratamento do Mal de Alzheimer
title_fullStr Produtos naturais como candidatos a fármacos úteis no tratamento do Mal de Alzheimer
title_full_unstemmed Produtos naturais como candidatos a fármacos úteis no tratamento do Mal de Alzheimer
title_sort Produtos naturais como candidatos a fármacos úteis no tratamento do Mal de Alzheimer
author Viegas Junior,Cláudio
author_facet Viegas Junior,Cláudio
Bolzani,Vanderlan da Silva
Furlan,Maysa
Fraga,Carlos Alberto Manssour
Barreiro,Eliezer J.
author_role author
author2 Bolzani,Vanderlan da Silva
Furlan,Maysa
Fraga,Carlos Alberto Manssour
Barreiro,Eliezer J.
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Viegas Junior,Cláudio
Bolzani,Vanderlan da Silva
Furlan,Maysa
Fraga,Carlos Alberto Manssour
Barreiro,Eliezer J.
dc.subject.por.fl_str_mv Alzheimer's disease
acetylcholinesterase
natural products
topic Alzheimer's disease
acetylcholinesterase
natural products
description Alzheimer's disease (AD) is a progressive neurodegenerative pathology with severe economic and social impact. There is currently no cure, although cholinesterase inhibitors provide effective temporary relief of symptoms in some patients. Nowadays drug research and development are based on the cholinergic hypothesis that supports the cognition improvement by regulation of the synthesis and release of acetylcholine in the brain. There are only four commercial medicines approved for treatment of AD and natural products have played an important role in the research for new acetylcholinesterase inhibitors.
publishDate 2004
dc.date.none.fl_str_mv 2004-08-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422004000400021
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422004000400021
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv 10.1590/S0100-40422004000400021
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dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Química
publisher.none.fl_str_mv Sociedade Brasileira de Química
dc.source.none.fl_str_mv Química Nova v.27 n.4 2004
reponame:Química Nova (Online)
instname:Sociedade Brasileira de Química (SBQ)
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reponame_str Química Nova (Online)
collection Química Nova (Online)
repository.name.fl_str_mv Química Nova (Online) - Sociedade Brasileira de Química (SBQ)
repository.mail.fl_str_mv quimicanova@sbq.org.br
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