Proteínas tirosina fosfatases: propriedades e funções biológicas

Detalhes bibliográficos
Autor(a) principal: Aoyama,Hiroshi
Data de Publicação: 2003
Outros Autores: Silva,Telma Maria Araújo, Miranda,Márcio André, Ferreira,Carmen Veríssima
Tipo de documento: Artigo
Idioma: por
Título da fonte: Química Nova (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422003000600019
Resumo: Protein phosphorylation-dephosphorylation catalyzed by the opposing and dynamic action of protein kinases and phosphatases probably, is the most crucial chemical reaction taking place in living organisms. Protein phosphatases are classified according to their substrate specificity and sensitivity to inhibitory or activator agents, into two families of protein phosphatases: serine/threonine phosphatases and tyrosine phosphatases (PTPs). PTPs can be divided into 3 groups: tyrosine specific phosphatases, dual and low molecular weight phosphatases. The role of tyrosine phosphorylation in mitogenic signaling is well documented, and one would predict that vanadate, pervanadate and other oxidant agents (protein tyrosine phosphatase inhibitors) may act as a growth stimulator.
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spelling Proteínas tirosina fosfatases: propriedades e funções biológicasprotein tyrosine phosphatasessignal transductionbiological functionProtein phosphorylation-dephosphorylation catalyzed by the opposing and dynamic action of protein kinases and phosphatases probably, is the most crucial chemical reaction taking place in living organisms. Protein phosphatases are classified according to their substrate specificity and sensitivity to inhibitory or activator agents, into two families of protein phosphatases: serine/threonine phosphatases and tyrosine phosphatases (PTPs). PTPs can be divided into 3 groups: tyrosine specific phosphatases, dual and low molecular weight phosphatases. The role of tyrosine phosphorylation in mitogenic signaling is well documented, and one would predict that vanadate, pervanadate and other oxidant agents (protein tyrosine phosphatase inhibitors) may act as a growth stimulator.Sociedade Brasileira de Química2003-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422003000600019Química Nova v.26 n.6 2003reponame:Química Nova (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.1590/S0100-40422003000600019info:eu-repo/semantics/openAccessAoyama,HiroshiSilva,Telma Maria AraújoMiranda,Márcio AndréFerreira,Carmen Veríssimapor2003-12-03T00:00:00Zoai:scielo:S0100-40422003000600019Revistahttps://www.scielo.br/j/qn/ONGhttps://old.scielo.br/oai/scielo-oai.phpquimicanova@sbq.org.br1678-70640100-4042opendoar:2003-12-03T00:00Química Nova (Online) - Sociedade Brasileira de Química (SBQ)false
dc.title.none.fl_str_mv Proteínas tirosina fosfatases: propriedades e funções biológicas
title Proteínas tirosina fosfatases: propriedades e funções biológicas
spellingShingle Proteínas tirosina fosfatases: propriedades e funções biológicas
Aoyama,Hiroshi
protein tyrosine phosphatases
signal transduction
biological function
title_short Proteínas tirosina fosfatases: propriedades e funções biológicas
title_full Proteínas tirosina fosfatases: propriedades e funções biológicas
title_fullStr Proteínas tirosina fosfatases: propriedades e funções biológicas
title_full_unstemmed Proteínas tirosina fosfatases: propriedades e funções biológicas
title_sort Proteínas tirosina fosfatases: propriedades e funções biológicas
author Aoyama,Hiroshi
author_facet Aoyama,Hiroshi
Silva,Telma Maria Araújo
Miranda,Márcio André
Ferreira,Carmen Veríssima
author_role author
author2 Silva,Telma Maria Araújo
Miranda,Márcio André
Ferreira,Carmen Veríssima
author2_role author
author
author
dc.contributor.author.fl_str_mv Aoyama,Hiroshi
Silva,Telma Maria Araújo
Miranda,Márcio André
Ferreira,Carmen Veríssima
dc.subject.por.fl_str_mv protein tyrosine phosphatases
signal transduction
biological function
topic protein tyrosine phosphatases
signal transduction
biological function
description Protein phosphorylation-dephosphorylation catalyzed by the opposing and dynamic action of protein kinases and phosphatases probably, is the most crucial chemical reaction taking place in living organisms. Protein phosphatases are classified according to their substrate specificity and sensitivity to inhibitory or activator agents, into two families of protein phosphatases: serine/threonine phosphatases and tyrosine phosphatases (PTPs). PTPs can be divided into 3 groups: tyrosine specific phosphatases, dual and low molecular weight phosphatases. The role of tyrosine phosphorylation in mitogenic signaling is well documented, and one would predict that vanadate, pervanadate and other oxidant agents (protein tyrosine phosphatase inhibitors) may act as a growth stimulator.
publishDate 2003
dc.date.none.fl_str_mv 2003-12-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422003000600019
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422003000600019
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv 10.1590/S0100-40422003000600019
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Química
publisher.none.fl_str_mv Sociedade Brasileira de Química
dc.source.none.fl_str_mv Química Nova v.26 n.6 2003
reponame:Química Nova (Online)
instname:Sociedade Brasileira de Química (SBQ)
instacron:SBQ
instname_str Sociedade Brasileira de Química (SBQ)
instacron_str SBQ
institution SBQ
reponame_str Química Nova (Online)
collection Química Nova (Online)
repository.name.fl_str_mv Química Nova (Online) - Sociedade Brasileira de Química (SBQ)
repository.mail.fl_str_mv quimicanova@sbq.org.br
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