OPTIMIZATION OF SOLVENT-FREE GERANYL BUTANOATE PRODUCTION USING NOVOZYME 435 AND HOMEMADE POLYURETHANE IMMOBILIZED NOVOZYME NZL-102-LYO-HQ AS CATALYSTS

• Autor(a) principal: Sbardelotto,Carla R.
• Data de Publicação: 2018
• Outros Autores: Piazza,Suelen P., Nyari,Nadia L. D., Dallago,Rogério M., Oliveira,Débora de, Oliveira,Vladimir de, Zeni,Jamile, Cansian,Rogério L., Paroul,Natalia
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Química Nova (Online)
• Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422018000800905
• topic: esterification; geranyl butanoate; Novozyme 435; Novozyme NZL-102-LYO-HQ

This study reports the optimization of geranyl butanoate production by esterification of geraniol and butanoic acid in a solvent-free system using two immobilized lipases as catalyst. The operating conditions that optimized geranyl butanoate production were determined to be 40 °C, a geraniol to butanoic acid molar ratio of 3:1, 150 rpm, 5 wt% of enzyme, and 1 h of reaction, which resulted in a reaction conversion of about 97% for Novozyme 435. When homemade Novozyme NZL-102-LYO-HQ (Cal-B) immobilized in polyurethane foam was used as catalyst, the experimental conditions of an alcohol to acid molar ratio of 5:1, 70 °C, 150 rpm, 5 wt% of enzyme, and 1 h of reaction gave a conversion of 95%. New experimental data on enzymatic esterification of geraniol and butanoic acid for geranyl butanoate production are reported in this work, showing that the technique is promising for overcoming the well-known drawbacks of the chemical-catalyzed route.