Análise de fármacos em águas por SPE-UPLC-ESI-MS/MS
Autor(a) principal: | |
---|---|
Data de Publicação: | 2014 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Química Nova (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422014000100023 |
Resumo: | A method was developed for the analysis of 31 pharmaceutical compounds in Lisbon's drinking water system, using solid-phase extraction (SPE) and ultra-performance liquid chromatography coupled to tandem mass spectrometry (UPLC-MS/MS). The method was validated through estimation of the linearity range, method detection and quantification limits, matrix effects, precision and accuracy. The method detection and quantification limit ranges were 0.009-10 and 0.03-33 ng/L, respectively. Analytes were quantified in water samples collected from the EPAL (Empresa Portuguesa das Águas Livres S.A.) supply system. Carbamazepine, atenolol, sulfadiazine, sulfamethazine, sulfapyridine, sulfamethoxazole, acetaminophen, caffeine and erythromycin were quantified in the analysed samples. |
id |
SBQ-3_d4f83c8d11fa9e0dcce6d4cdf7998e21 |
---|---|
oai_identifier_str |
oai:scielo:S0100-40422014000100023 |
network_acronym_str |
SBQ-3 |
network_name_str |
Química Nova (Online) |
repository_id_str |
|
spelling |
Análise de fármacos em águas por SPE-UPLC-ESI-MS/MSwaterpharmaceutical compoundsUPLC-MS/MSA method was developed for the analysis of 31 pharmaceutical compounds in Lisbon's drinking water system, using solid-phase extraction (SPE) and ultra-performance liquid chromatography coupled to tandem mass spectrometry (UPLC-MS/MS). The method was validated through estimation of the linearity range, method detection and quantification limits, matrix effects, precision and accuracy. The method detection and quantification limit ranges were 0.009-10 and 0.03-33 ng/L, respectively. Analytes were quantified in water samples collected from the EPAL (Empresa Portuguesa das Águas Livres S.A.) supply system. Carbamazepine, atenolol, sulfadiazine, sulfamethazine, sulfapyridine, sulfamethoxazole, acetaminophen, caffeine and erythromycin were quantified in the analysed samples.Sociedade Brasileira de Química2014-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422014000100023Química Nova v.37 n.1 2014reponame:Química Nova (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.1590/S0100-40422014000100023info:eu-repo/semantics/openAccessGaffney,Vanessa de JesusCardoso,Vitor ValeRodrigues,AlexandreFerreira,ElisabeteBenoliel,Maria JoãoAlmeida,Cristina M. M.por2014-02-18T00:00:00Zoai:scielo:S0100-40422014000100023Revistahttps://www.scielo.br/j/qn/ONGhttps://old.scielo.br/oai/scielo-oai.phpquimicanova@sbq.org.br1678-70640100-4042opendoar:2014-02-18T00:00Química Nova (Online) - Sociedade Brasileira de Química (SBQ)false |
dc.title.none.fl_str_mv |
Análise de fármacos em águas por SPE-UPLC-ESI-MS/MS |
title |
Análise de fármacos em águas por SPE-UPLC-ESI-MS/MS |
spellingShingle |
Análise de fármacos em águas por SPE-UPLC-ESI-MS/MS Gaffney,Vanessa de Jesus water pharmaceutical compounds UPLC-MS/MS |
title_short |
Análise de fármacos em águas por SPE-UPLC-ESI-MS/MS |
title_full |
Análise de fármacos em águas por SPE-UPLC-ESI-MS/MS |
title_fullStr |
Análise de fármacos em águas por SPE-UPLC-ESI-MS/MS |
title_full_unstemmed |
Análise de fármacos em águas por SPE-UPLC-ESI-MS/MS |
title_sort |
Análise de fármacos em águas por SPE-UPLC-ESI-MS/MS |
author |
Gaffney,Vanessa de Jesus |
author_facet |
Gaffney,Vanessa de Jesus Cardoso,Vitor Vale Rodrigues,Alexandre Ferreira,Elisabete Benoliel,Maria João Almeida,Cristina M. M. |
author_role |
author |
author2 |
Cardoso,Vitor Vale Rodrigues,Alexandre Ferreira,Elisabete Benoliel,Maria João Almeida,Cristina M. M. |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Gaffney,Vanessa de Jesus Cardoso,Vitor Vale Rodrigues,Alexandre Ferreira,Elisabete Benoliel,Maria João Almeida,Cristina M. M. |
dc.subject.por.fl_str_mv |
water pharmaceutical compounds UPLC-MS/MS |
topic |
water pharmaceutical compounds UPLC-MS/MS |
description |
A method was developed for the analysis of 31 pharmaceutical compounds in Lisbon's drinking water system, using solid-phase extraction (SPE) and ultra-performance liquid chromatography coupled to tandem mass spectrometry (UPLC-MS/MS). The method was validated through estimation of the linearity range, method detection and quantification limits, matrix effects, precision and accuracy. The method detection and quantification limit ranges were 0.009-10 and 0.03-33 ng/L, respectively. Analytes were quantified in water samples collected from the EPAL (Empresa Portuguesa das Águas Livres S.A.) supply system. Carbamazepine, atenolol, sulfadiazine, sulfamethazine, sulfapyridine, sulfamethoxazole, acetaminophen, caffeine and erythromycin were quantified in the analysed samples. |
publishDate |
2014 |
dc.date.none.fl_str_mv |
2014-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422014000100023 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422014000100023 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
10.1590/S0100-40422014000100023 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Química |
publisher.none.fl_str_mv |
Sociedade Brasileira de Química |
dc.source.none.fl_str_mv |
Química Nova v.37 n.1 2014 reponame:Química Nova (Online) instname:Sociedade Brasileira de Química (SBQ) instacron:SBQ |
instname_str |
Sociedade Brasileira de Química (SBQ) |
instacron_str |
SBQ |
institution |
SBQ |
reponame_str |
Química Nova (Online) |
collection |
Química Nova (Online) |
repository.name.fl_str_mv |
Química Nova (Online) - Sociedade Brasileira de Química (SBQ) |
repository.mail.fl_str_mv |
quimicanova@sbq.org.br |
_version_ |
1750318115499016192 |