Métodos de obtenção, reatividade e importância biológica de 4-tiazolidinonas

Detalhes bibliográficos
Autor(a) principal: Liesen,André P.
Data de Publicação: 2008
Outros Autores: Aquino,Thiago M. de, Góes,Alexandre J. S., Lima,José G. de, Faria,Antônio R. de, Alves,Antonio J.
Tipo de documento: Artigo
Idioma: por
Título da fonte: Química Nova (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422008000200033
Resumo: Molecules containing the 4-thiazolidinone ring are known to possess a wide range of biological properties including antimicrobial and anti-inflammatory activities among others. These compounds can be synthesized by cyclization reactions involving alpha-haloacetic acid or alpha-mercaptoacetic acid and employed in several chemoselective reactions. Comprehensive reviews have been written on 4-thiazolidinones in 1961 by Brown and in 1980 by Singh et al. In the recent literature, some new synthesis methods for 4-thiazolidinone derivatives and several reactions have been reported. These advances warrant to review the chemical and biological properties of compounds with this important heterocycle employed in synthetic organic chemistry and medicinal chemistry.
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spelling Métodos de obtenção, reatividade e importância biológica de 4-tiazolidinonas4-thiazolidinonepreparation methodsreactivityMolecules containing the 4-thiazolidinone ring are known to possess a wide range of biological properties including antimicrobial and anti-inflammatory activities among others. These compounds can be synthesized by cyclization reactions involving alpha-haloacetic acid or alpha-mercaptoacetic acid and employed in several chemoselective reactions. Comprehensive reviews have been written on 4-thiazolidinones in 1961 by Brown and in 1980 by Singh et al. In the recent literature, some new synthesis methods for 4-thiazolidinone derivatives and several reactions have been reported. These advances warrant to review the chemical and biological properties of compounds with this important heterocycle employed in synthetic organic chemistry and medicinal chemistry.Sociedade Brasileira de Química2008-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422008000200033Química Nova v.31 n.2 2008reponame:Química Nova (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.1590/S0100-40422008000200033info:eu-repo/semantics/openAccessLiesen,André P.Aquino,Thiago M. deGóes,Alexandre J. S.Lima,José G. deFaria,Antônio R. deAlves,Antonio J.por2009-09-25T00:00:00Zoai:scielo:S0100-40422008000200033Revistahttps://www.scielo.br/j/qn/ONGhttps://old.scielo.br/oai/scielo-oai.phpquimicanova@sbq.org.br1678-70640100-4042opendoar:2009-09-25T00:00Química Nova (Online) - Sociedade Brasileira de Química (SBQ)false
dc.title.none.fl_str_mv Métodos de obtenção, reatividade e importância biológica de 4-tiazolidinonas
title Métodos de obtenção, reatividade e importância biológica de 4-tiazolidinonas
spellingShingle Métodos de obtenção, reatividade e importância biológica de 4-tiazolidinonas
Liesen,André P.
4-thiazolidinone
preparation methods
reactivity
title_short Métodos de obtenção, reatividade e importância biológica de 4-tiazolidinonas
title_full Métodos de obtenção, reatividade e importância biológica de 4-tiazolidinonas
title_fullStr Métodos de obtenção, reatividade e importância biológica de 4-tiazolidinonas
title_full_unstemmed Métodos de obtenção, reatividade e importância biológica de 4-tiazolidinonas
title_sort Métodos de obtenção, reatividade e importância biológica de 4-tiazolidinonas
author Liesen,André P.
author_facet Liesen,André P.
Aquino,Thiago M. de
Góes,Alexandre J. S.
Lima,José G. de
Faria,Antônio R. de
Alves,Antonio J.
author_role author
author2 Aquino,Thiago M. de
Góes,Alexandre J. S.
Lima,José G. de
Faria,Antônio R. de
Alves,Antonio J.
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Liesen,André P.
Aquino,Thiago M. de
Góes,Alexandre J. S.
Lima,José G. de
Faria,Antônio R. de
Alves,Antonio J.
dc.subject.por.fl_str_mv 4-thiazolidinone
preparation methods
reactivity
topic 4-thiazolidinone
preparation methods
reactivity
description Molecules containing the 4-thiazolidinone ring are known to possess a wide range of biological properties including antimicrobial and anti-inflammatory activities among others. These compounds can be synthesized by cyclization reactions involving alpha-haloacetic acid or alpha-mercaptoacetic acid and employed in several chemoselective reactions. Comprehensive reviews have been written on 4-thiazolidinones in 1961 by Brown and in 1980 by Singh et al. In the recent literature, some new synthesis methods for 4-thiazolidinone derivatives and several reactions have been reported. These advances warrant to review the chemical and biological properties of compounds with this important heterocycle employed in synthetic organic chemistry and medicinal chemistry.
publishDate 2008
dc.date.none.fl_str_mv 2008-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422008000200033
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422008000200033
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv 10.1590/S0100-40422008000200033
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Química
publisher.none.fl_str_mv Sociedade Brasileira de Química
dc.source.none.fl_str_mv Química Nova v.31 n.2 2008
reponame:Química Nova (Online)
instname:Sociedade Brasileira de Química (SBQ)
instacron:SBQ
instname_str Sociedade Brasileira de Química (SBQ)
instacron_str SBQ
institution SBQ
reponame_str Química Nova (Online)
collection Química Nova (Online)
repository.name.fl_str_mv Química Nova (Online) - Sociedade Brasileira de Química (SBQ)
repository.mail.fl_str_mv quimicanova@sbq.org.br
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