Antifungal derivatives from Piper mollicomum and P. lhotzkyanum (Piperaceae)
Autor(a) principal: | |
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Data de Publicação: | 2007 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Química Nova (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422007000500032 |
Resumo: | Bioguided fractionation of the extracts from leaves of Piper mollicomum and Piper lhotzkyanum against the fungi Cladosporium cladosporioides and C. sphaerospermum afforded seven bioactive compounds, four being chromenes: methyl 2,2-dimethyl-2H-chromene-6-carboxylate, methyl 8-hydroxy-2,2-dimethyl-2H-chromene-6-carboxylate, 2-methyl-2-[4'-methyl-3'-pentenyl]-2H-1-benzopyran-6-carboxylic acid, 2,2-dimethyl-2H-chromene-6-carboxylic acid, one a dihydrochalcone: 2',6'-dihydroxy-4'-methoxydihydrochalcone, and two flavanones: 7-methoxy-5,4'-dihydroxy-flavanone and 7,4'-dimethoxy-5-hydroxy-flavanone. The structures of the bioactive isolated derivatives were elucidated by interpretation of their NMR data [¹H and 13C (BBD, DEPT 135º)], and mass spectral data as well as by comparison with data described in the literature. |
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Antifungal derivatives from Piper mollicomum and P. lhotzkyanum (Piperaceae)Piper mollicomumPiper lhotzkyanumantifungal derivativesBioguided fractionation of the extracts from leaves of Piper mollicomum and Piper lhotzkyanum against the fungi Cladosporium cladosporioides and C. sphaerospermum afforded seven bioactive compounds, four being chromenes: methyl 2,2-dimethyl-2H-chromene-6-carboxylate, methyl 8-hydroxy-2,2-dimethyl-2H-chromene-6-carboxylate, 2-methyl-2-[4'-methyl-3'-pentenyl]-2H-1-benzopyran-6-carboxylic acid, 2,2-dimethyl-2H-chromene-6-carboxylic acid, one a dihydrochalcone: 2',6'-dihydroxy-4'-methoxydihydrochalcone, and two flavanones: 7-methoxy-5,4'-dihydroxy-flavanone and 7,4'-dimethoxy-5-hydroxy-flavanone. The structures of the bioactive isolated derivatives were elucidated by interpretation of their NMR data [¹H and 13C (BBD, DEPT 135º)], and mass spectral data as well as by comparison with data described in the literature.Sociedade Brasileira de Química2007-10-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422007000500032Química Nova v.30 n.5 2007reponame:Química Nova (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.1590/S0100-40422007000500032info:eu-repo/semantics/openAccessLago,João Henrique G.Young,Maria Claudia M.Reigada,Juliana B.Soares,Marisi G.Roesler,Bianca P.Kato,Massuo J.eng2007-09-28T00:00:00Zoai:scielo:S0100-40422007000500032Revistahttps://www.scielo.br/j/qn/ONGhttps://old.scielo.br/oai/scielo-oai.phpquimicanova@sbq.org.br1678-70640100-4042opendoar:2007-09-28T00:00Química Nova (Online) - Sociedade Brasileira de Química (SBQ)false |
dc.title.none.fl_str_mv |
Antifungal derivatives from Piper mollicomum and P. lhotzkyanum (Piperaceae) |
title |
Antifungal derivatives from Piper mollicomum and P. lhotzkyanum (Piperaceae) |
spellingShingle |
Antifungal derivatives from Piper mollicomum and P. lhotzkyanum (Piperaceae) Lago,João Henrique G. Piper mollicomum Piper lhotzkyanum antifungal derivatives |
title_short |
Antifungal derivatives from Piper mollicomum and P. lhotzkyanum (Piperaceae) |
title_full |
Antifungal derivatives from Piper mollicomum and P. lhotzkyanum (Piperaceae) |
title_fullStr |
Antifungal derivatives from Piper mollicomum and P. lhotzkyanum (Piperaceae) |
title_full_unstemmed |
Antifungal derivatives from Piper mollicomum and P. lhotzkyanum (Piperaceae) |
title_sort |
Antifungal derivatives from Piper mollicomum and P. lhotzkyanum (Piperaceae) |
author |
Lago,João Henrique G. |
author_facet |
Lago,João Henrique G. Young,Maria Claudia M. Reigada,Juliana B. Soares,Marisi G. Roesler,Bianca P. Kato,Massuo J. |
author_role |
author |
author2 |
Young,Maria Claudia M. Reigada,Juliana B. Soares,Marisi G. Roesler,Bianca P. Kato,Massuo J. |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Lago,João Henrique G. Young,Maria Claudia M. Reigada,Juliana B. Soares,Marisi G. Roesler,Bianca P. Kato,Massuo J. |
dc.subject.por.fl_str_mv |
Piper mollicomum Piper lhotzkyanum antifungal derivatives |
topic |
Piper mollicomum Piper lhotzkyanum antifungal derivatives |
description |
Bioguided fractionation of the extracts from leaves of Piper mollicomum and Piper lhotzkyanum against the fungi Cladosporium cladosporioides and C. sphaerospermum afforded seven bioactive compounds, four being chromenes: methyl 2,2-dimethyl-2H-chromene-6-carboxylate, methyl 8-hydroxy-2,2-dimethyl-2H-chromene-6-carboxylate, 2-methyl-2-[4'-methyl-3'-pentenyl]-2H-1-benzopyran-6-carboxylic acid, 2,2-dimethyl-2H-chromene-6-carboxylic acid, one a dihydrochalcone: 2',6'-dihydroxy-4'-methoxydihydrochalcone, and two flavanones: 7-methoxy-5,4'-dihydroxy-flavanone and 7,4'-dimethoxy-5-hydroxy-flavanone. The structures of the bioactive isolated derivatives were elucidated by interpretation of their NMR data [¹H and 13C (BBD, DEPT 135º)], and mass spectral data as well as by comparison with data described in the literature. |
publishDate |
2007 |
dc.date.none.fl_str_mv |
2007-10-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422007000500032 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422007000500032 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0100-40422007000500032 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Química |
publisher.none.fl_str_mv |
Sociedade Brasileira de Química |
dc.source.none.fl_str_mv |
Química Nova v.30 n.5 2007 reponame:Química Nova (Online) instname:Sociedade Brasileira de Química (SBQ) instacron:SBQ |
instname_str |
Sociedade Brasileira de Química (SBQ) |
instacron_str |
SBQ |
institution |
SBQ |
reponame_str |
Química Nova (Online) |
collection |
Química Nova (Online) |
repository.name.fl_str_mv |
Química Nova (Online) - Sociedade Brasileira de Química (SBQ) |
repository.mail.fl_str_mv |
quimicanova@sbq.org.br |
_version_ |
1750318106530545664 |