STRAIGHTFORWARD, ECONOMICAL PROCEDURES FOR MICROSCALE ELLMAN'S TEST FOR CHOLINESTERASE INHIBITION AND REACTIVATION

Detalhes bibliográficos
Autor(a) principal: Cavalcante,Samir F. de A.
Data de Publicação: 2018
Outros Autores: Kitagawa,Daniel A. S., Rodrigues,Rafael B., Cardozo,Monique, Paula,Reuel L. de, Correa,Ana Beatriz de A., Simas,Alessandro B. C.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Química Nova (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422018001001192
Resumo: Straightforward, microscale, Ellman's cholinesterase test procedures are presented, useful for screening of novel compounds aiming at neurodegenerative diseases and antidotes towards nerve agents and pesticides. Herein, we detail the different procedure features and set forth guidelines on experimental choices researchers may make. The detailed procedure lowers the costs for Ellman´s test, what is highly desirable for low-budget groups in science-lagging and developing countries.
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spelling STRAIGHTFORWARD, ECONOMICAL PROCEDURES FOR MICROSCALE ELLMAN'S TEST FOR CHOLINESTERASE INHIBITION AND REACTIVATIONEllman's testcholinesteraseneurodegenerative diseasesnerve agentspesticidesStraightforward, microscale, Ellman's cholinesterase test procedures are presented, useful for screening of novel compounds aiming at neurodegenerative diseases and antidotes towards nerve agents and pesticides. Herein, we detail the different procedure features and set forth guidelines on experimental choices researchers may make. The detailed procedure lowers the costs for Ellman´s test, what is highly desirable for low-budget groups in science-lagging and developing countries.Sociedade Brasileira de Química2018-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422018001001192Química Nova v.41 n.10 2018reponame:Química Nova (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.21577/0100-4042.20170278info:eu-repo/semantics/openAccessCavalcante,Samir F. de A.Kitagawa,Daniel A. S.Rodrigues,Rafael B.Cardozo,MoniquePaula,Reuel L. deCorrea,Ana Beatriz de A.Simas,Alessandro B. C.eng2018-12-03T00:00:00Zoai:scielo:S0100-40422018001001192Revistahttps://www.scielo.br/j/qn/ONGhttps://old.scielo.br/oai/scielo-oai.phpquimicanova@sbq.org.br1678-70640100-4042opendoar:2018-12-03T00:00Química Nova (Online) - Sociedade Brasileira de Química (SBQ)false
dc.title.none.fl_str_mv STRAIGHTFORWARD, ECONOMICAL PROCEDURES FOR MICROSCALE ELLMAN'S TEST FOR CHOLINESTERASE INHIBITION AND REACTIVATION
title STRAIGHTFORWARD, ECONOMICAL PROCEDURES FOR MICROSCALE ELLMAN'S TEST FOR CHOLINESTERASE INHIBITION AND REACTIVATION
spellingShingle STRAIGHTFORWARD, ECONOMICAL PROCEDURES FOR MICROSCALE ELLMAN'S TEST FOR CHOLINESTERASE INHIBITION AND REACTIVATION
Cavalcante,Samir F. de A.
Ellman's test
cholinesterase
neurodegenerative diseases
nerve agents
pesticides
title_short STRAIGHTFORWARD, ECONOMICAL PROCEDURES FOR MICROSCALE ELLMAN'S TEST FOR CHOLINESTERASE INHIBITION AND REACTIVATION
title_full STRAIGHTFORWARD, ECONOMICAL PROCEDURES FOR MICROSCALE ELLMAN'S TEST FOR CHOLINESTERASE INHIBITION AND REACTIVATION
title_fullStr STRAIGHTFORWARD, ECONOMICAL PROCEDURES FOR MICROSCALE ELLMAN'S TEST FOR CHOLINESTERASE INHIBITION AND REACTIVATION
title_full_unstemmed STRAIGHTFORWARD, ECONOMICAL PROCEDURES FOR MICROSCALE ELLMAN'S TEST FOR CHOLINESTERASE INHIBITION AND REACTIVATION
title_sort STRAIGHTFORWARD, ECONOMICAL PROCEDURES FOR MICROSCALE ELLMAN'S TEST FOR CHOLINESTERASE INHIBITION AND REACTIVATION
author Cavalcante,Samir F. de A.
author_facet Cavalcante,Samir F. de A.
Kitagawa,Daniel A. S.
Rodrigues,Rafael B.
Cardozo,Monique
Paula,Reuel L. de
Correa,Ana Beatriz de A.
Simas,Alessandro B. C.
author_role author
author2 Kitagawa,Daniel A. S.
Rodrigues,Rafael B.
Cardozo,Monique
Paula,Reuel L. de
Correa,Ana Beatriz de A.
Simas,Alessandro B. C.
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Cavalcante,Samir F. de A.
Kitagawa,Daniel A. S.
Rodrigues,Rafael B.
Cardozo,Monique
Paula,Reuel L. de
Correa,Ana Beatriz de A.
Simas,Alessandro B. C.
dc.subject.por.fl_str_mv Ellman's test
cholinesterase
neurodegenerative diseases
nerve agents
pesticides
topic Ellman's test
cholinesterase
neurodegenerative diseases
nerve agents
pesticides
description Straightforward, microscale, Ellman's cholinesterase test procedures are presented, useful for screening of novel compounds aiming at neurodegenerative diseases and antidotes towards nerve agents and pesticides. Herein, we detail the different procedure features and set forth guidelines on experimental choices researchers may make. The detailed procedure lowers the costs for Ellman´s test, what is highly desirable for low-budget groups in science-lagging and developing countries.
publishDate 2018
dc.date.none.fl_str_mv 2018-12-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422018001001192
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422018001001192
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.21577/0100-4042.20170278
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Química
publisher.none.fl_str_mv Sociedade Brasileira de Química
dc.source.none.fl_str_mv Química Nova v.41 n.10 2018
reponame:Química Nova (Online)
instname:Sociedade Brasileira de Química (SBQ)
instacron:SBQ
instname_str Sociedade Brasileira de Química (SBQ)
instacron_str SBQ
institution SBQ
reponame_str Química Nova (Online)
collection Química Nova (Online)
repository.name.fl_str_mv Química Nova (Online) - Sociedade Brasileira de Química (SBQ)
repository.mail.fl_str_mv quimicanova@sbq.org.br
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