Fc gamma receptor IIIa polymorphism is not associated with susceptibility to systemic lupus erythematosus in Brazilian patients

Detalhes bibliográficos
Autor(a) principal: Grecco,Marcelle
Data de Publicação: 2016
Outros Autores: Santos,Viviane Cardoso dos, Pereira,Kaline Medeiros Costa, Andrade,Luís Eduardo Coelho, Silva,Neusa Pereira da
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista Brasileira de Reumatologia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0482-50042016000600515
Resumo: ABSTRACT We evaluated the possible association between FCGR3A V/F (158) polymorphism and SLE susceptibility and clinical phenotype in 305 sequentially retrieved SLE patients and 300 healthy controls from the southeastern part of Brazil by allele-specific polymerase chain reaction. Our results showed no association between FCGR3A 158V/F alleles and susceptibility to SLE in this series of patients albeit the heterozygous genotype was strongly associated with the disease.
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spelling Fc gamma receptor IIIa polymorphism is not associated with susceptibility to systemic lupus erythematosus in Brazilian patientsSystemic lupus erythematosusFc gamma receptor IIIaSingle nucleotide polymorphismGene polymorphismImmunogeneticsABSTRACT We evaluated the possible association between FCGR3A V/F (158) polymorphism and SLE susceptibility and clinical phenotype in 305 sequentially retrieved SLE patients and 300 healthy controls from the southeastern part of Brazil by allele-specific polymerase chain reaction. Our results showed no association between FCGR3A 158V/F alleles and susceptibility to SLE in this series of patients albeit the heterozygous genotype was strongly associated with the disease.Sociedade Brasileira de Reumatologia2016-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0482-50042016000600515Revista Brasileira de Reumatologia v.56 n.6 2016reponame:Revista Brasileira de Reumatologia (Online)instname:Sociedade Brasileira de Reumatologia (SBR)instacron:SBR10.1016/j.rbre.2016.07.013info:eu-repo/semantics/openAccessGrecco,MarcelleSantos,Viviane Cardoso dosPereira,Kaline Medeiros CostaAndrade,Luís Eduardo CoelhoSilva,Neusa Pereira daeng2016-12-15T00:00:00Zoai:scielo:S0482-50042016000600515Revistahttp://www.scielo.br/scielo.php?script=sci_serial&pid=0482-5004&lng=pt&nrm=isoONGhttps://old.scielo.br/oai/scielo-oai.php||sbre@terra.com.br1809-45700482-5004opendoar:2016-12-15T00:00Revista Brasileira de Reumatologia (Online) - Sociedade Brasileira de Reumatologia (SBR)false
dc.title.none.fl_str_mv Fc gamma receptor IIIa polymorphism is not associated with susceptibility to systemic lupus erythematosus in Brazilian patients
title Fc gamma receptor IIIa polymorphism is not associated with susceptibility to systemic lupus erythematosus in Brazilian patients
spellingShingle Fc gamma receptor IIIa polymorphism is not associated with susceptibility to systemic lupus erythematosus in Brazilian patients
Grecco,Marcelle
Systemic lupus erythematosus
Fc gamma receptor IIIa
Single nucleotide polymorphism
Gene polymorphism
Immunogenetics
title_short Fc gamma receptor IIIa polymorphism is not associated with susceptibility to systemic lupus erythematosus in Brazilian patients
title_full Fc gamma receptor IIIa polymorphism is not associated with susceptibility to systemic lupus erythematosus in Brazilian patients
title_fullStr Fc gamma receptor IIIa polymorphism is not associated with susceptibility to systemic lupus erythematosus in Brazilian patients
title_full_unstemmed Fc gamma receptor IIIa polymorphism is not associated with susceptibility to systemic lupus erythematosus in Brazilian patients
title_sort Fc gamma receptor IIIa polymorphism is not associated with susceptibility to systemic lupus erythematosus in Brazilian patients
author Grecco,Marcelle
author_facet Grecco,Marcelle
Santos,Viviane Cardoso dos
Pereira,Kaline Medeiros Costa
Andrade,Luís Eduardo Coelho
Silva,Neusa Pereira da
author_role author
author2 Santos,Viviane Cardoso dos
Pereira,Kaline Medeiros Costa
Andrade,Luís Eduardo Coelho
Silva,Neusa Pereira da
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Grecco,Marcelle
Santos,Viviane Cardoso dos
Pereira,Kaline Medeiros Costa
Andrade,Luís Eduardo Coelho
Silva,Neusa Pereira da
dc.subject.por.fl_str_mv Systemic lupus erythematosus
Fc gamma receptor IIIa
Single nucleotide polymorphism
Gene polymorphism
Immunogenetics
topic Systemic lupus erythematosus
Fc gamma receptor IIIa
Single nucleotide polymorphism
Gene polymorphism
Immunogenetics
description ABSTRACT We evaluated the possible association between FCGR3A V/F (158) polymorphism and SLE susceptibility and clinical phenotype in 305 sequentially retrieved SLE patients and 300 healthy controls from the southeastern part of Brazil by allele-specific polymerase chain reaction. Our results showed no association between FCGR3A 158V/F alleles and susceptibility to SLE in this series of patients albeit the heterozygous genotype was strongly associated with the disease.
publishDate 2016
dc.date.none.fl_str_mv 2016-12-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0482-50042016000600515
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0482-50042016000600515
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1016/j.rbre.2016.07.013
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Reumatologia
publisher.none.fl_str_mv Sociedade Brasileira de Reumatologia
dc.source.none.fl_str_mv Revista Brasileira de Reumatologia v.56 n.6 2016
reponame:Revista Brasileira de Reumatologia (Online)
instname:Sociedade Brasileira de Reumatologia (SBR)
instacron:SBR
instname_str Sociedade Brasileira de Reumatologia (SBR)
instacron_str SBR
institution SBR
reponame_str Revista Brasileira de Reumatologia (Online)
collection Revista Brasileira de Reumatologia (Online)
repository.name.fl_str_mv Revista Brasileira de Reumatologia (Online) - Sociedade Brasileira de Reumatologia (SBR)
repository.mail.fl_str_mv ||sbre@terra.com.br
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