Platelet-rich plasma for osteoarthritis treatment

Detalhes bibliográficos
Autor(a) principal: Knop,Eduardo
Data de Publicação: 2016
Outros Autores: Paula,Luiz Eduardo de, Fuller,Ricardo
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista Brasileira de Reumatologia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0482-50042016000200152
Resumo: ABSTRACT We conducted a comprehensive and systematic search of the literature on the use of platelet-rich plasma (PRP) in the treatment of osteoarthritis, using the Medline, Lilacs, Cochrane and SciELO databases, from May 2012 to October 2013. A total of 23 studies were selected, with nine being controlled trials and, of these, seven randomized, which included 725 patients. In this series, the group receiving PRP showed improvement in pain and joint function compared to placebo and hyaluronic acid. The response lasted up to two years and was better in milder cases. However it was found that there is no standardization in the PRP production method, neither in the number, timing, and volume of applications. Furthermore, the populations studied were not clearly described in many studies. Thus, these results should be analyzed with caution, and further studies with more standardized methods would be necessary for a more consistent conclusion about the PRP role in osteoarthritis.
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spelling Platelet-rich plasma for osteoarthritis treatmentPlatelet-rich plasmaCartilageOsteoarthritisABSTRACT We conducted a comprehensive and systematic search of the literature on the use of platelet-rich plasma (PRP) in the treatment of osteoarthritis, using the Medline, Lilacs, Cochrane and SciELO databases, from May 2012 to October 2013. A total of 23 studies were selected, with nine being controlled trials and, of these, seven randomized, which included 725 patients. In this series, the group receiving PRP showed improvement in pain and joint function compared to placebo and hyaluronic acid. The response lasted up to two years and was better in milder cases. However it was found that there is no standardization in the PRP production method, neither in the number, timing, and volume of applications. Furthermore, the populations studied were not clearly described in many studies. Thus, these results should be analyzed with caution, and further studies with more standardized methods would be necessary for a more consistent conclusion about the PRP role in osteoarthritis.Sociedade Brasileira de Reumatologia2016-04-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0482-50042016000200152Revista Brasileira de Reumatologia v.56 n.2 2016reponame:Revista Brasileira de Reumatologia (Online)instname:Sociedade Brasileira de Reumatologia (SBR)instacron:SBR10.1016/j.rbre.2015.07.002info:eu-repo/semantics/openAccessKnop,EduardoPaula,Luiz Eduardo deFuller,Ricardoeng2016-04-27T00:00:00Zoai:scielo:S0482-50042016000200152Revistahttp://www.scielo.br/scielo.php?script=sci_serial&pid=0482-5004&lng=pt&nrm=isoONGhttps://old.scielo.br/oai/scielo-oai.php||sbre@terra.com.br1809-45700482-5004opendoar:2016-04-27T00:00Revista Brasileira de Reumatologia (Online) - Sociedade Brasileira de Reumatologia (SBR)false
dc.title.none.fl_str_mv Platelet-rich plasma for osteoarthritis treatment
title Platelet-rich plasma for osteoarthritis treatment
spellingShingle Platelet-rich plasma for osteoarthritis treatment
Knop,Eduardo
Platelet-rich plasma
Cartilage
Osteoarthritis
title_short Platelet-rich plasma for osteoarthritis treatment
title_full Platelet-rich plasma for osteoarthritis treatment
title_fullStr Platelet-rich plasma for osteoarthritis treatment
title_full_unstemmed Platelet-rich plasma for osteoarthritis treatment
title_sort Platelet-rich plasma for osteoarthritis treatment
author Knop,Eduardo
author_facet Knop,Eduardo
Paula,Luiz Eduardo de
Fuller,Ricardo
author_role author
author2 Paula,Luiz Eduardo de
Fuller,Ricardo
author2_role author
author
dc.contributor.author.fl_str_mv Knop,Eduardo
Paula,Luiz Eduardo de
Fuller,Ricardo
dc.subject.por.fl_str_mv Platelet-rich plasma
Cartilage
Osteoarthritis
topic Platelet-rich plasma
Cartilage
Osteoarthritis
description ABSTRACT We conducted a comprehensive and systematic search of the literature on the use of platelet-rich plasma (PRP) in the treatment of osteoarthritis, using the Medline, Lilacs, Cochrane and SciELO databases, from May 2012 to October 2013. A total of 23 studies were selected, with nine being controlled trials and, of these, seven randomized, which included 725 patients. In this series, the group receiving PRP showed improvement in pain and joint function compared to placebo and hyaluronic acid. The response lasted up to two years and was better in milder cases. However it was found that there is no standardization in the PRP production method, neither in the number, timing, and volume of applications. Furthermore, the populations studied were not clearly described in many studies. Thus, these results should be analyzed with caution, and further studies with more standardized methods would be necessary for a more consistent conclusion about the PRP role in osteoarthritis.
publishDate 2016
dc.date.none.fl_str_mv 2016-04-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0482-50042016000200152
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dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1016/j.rbre.2015.07.002
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eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Reumatologia
publisher.none.fl_str_mv Sociedade Brasileira de Reumatologia
dc.source.none.fl_str_mv Revista Brasileira de Reumatologia v.56 n.2 2016
reponame:Revista Brasileira de Reumatologia (Online)
instname:Sociedade Brasileira de Reumatologia (SBR)
instacron:SBR
instname_str Sociedade Brasileira de Reumatologia (SBR)
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reponame_str Revista Brasileira de Reumatologia (Online)
collection Revista Brasileira de Reumatologia (Online)
repository.name.fl_str_mv Revista Brasileira de Reumatologia (Online) - Sociedade Brasileira de Reumatologia (SBR)
repository.mail.fl_str_mv ||sbre@terra.com.br
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