Nonsecretory intestinocystoplasty: postoperative outcomes of 25 years

Detalhes bibliográficos
Autor(a) principal: Dantas,Rose A. F.
Data de Publicação: 2019
Outros Autores: Calisto,Fernanda C. F. S., Vilar,Fabio O., Araujo,Luiz A. P., Lima,Salvador V. C.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: International Braz J Urol (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382019000400681
Resumo: ABSTRACT Objective The objective of bladder augmentation (BA) is to create a low-pressure reservoir with adequate capacity. Despite its benefits, the use of intestinal patches in bladder enlargement provides a high risk of developing complications and BA with demucosalised bowel represents a potential alternative. Therefore, this study evaluated urological parameters and long-term clinical follow-up of patients submitted to non-secretory BA in a single center with 25 years of experience. Materials and Methods Patients treated with BA underwent urological evaluation, which included history, physical examination and urodynamic study. The main urodynamic parameters (bladder capacity and bladder compliance) were assessed in the pre and postoperative moments, and compared by the Wilcoxon Signed Rank test. The main long-term complications were described. Results 269 patients (mean age 14±13 years, 47% male) underwent BA with the use of demucolised intestinal segments. Among the patients in the sample, 187 (69.52%) had neurogenic bladder, 68 (25.28%) had bladder exstrophy, nine had tuberculosis (3.34%), four had a posterior urethral valve (1.49%) and one with hypospadia (0.37%). After the surgical procedure, a significant increment in both urodynamic parameters was found, with a 222% increase in bladder capacity and 604% in bladder compliance (p <0.001 in both analyzes). Mean follow-up time ranged from 2 to 358 months, with a median of 72 months (IQR 74-247). Among all patients, 5 presented spontaneous perforation. Conclusion The study showed statistically significant increase in both compliance and bladder capacity after non-secretory BA, with a low rate of severe complications.
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spelling Nonsecretory intestinocystoplasty: postoperative outcomes of 25 yearsHypopituitarismUrinary BladderDiseaseABSTRACT Objective The objective of bladder augmentation (BA) is to create a low-pressure reservoir with adequate capacity. Despite its benefits, the use of intestinal patches in bladder enlargement provides a high risk of developing complications and BA with demucosalised bowel represents a potential alternative. Therefore, this study evaluated urological parameters and long-term clinical follow-up of patients submitted to non-secretory BA in a single center with 25 years of experience. Materials and Methods Patients treated with BA underwent urological evaluation, which included history, physical examination and urodynamic study. The main urodynamic parameters (bladder capacity and bladder compliance) were assessed in the pre and postoperative moments, and compared by the Wilcoxon Signed Rank test. The main long-term complications were described. Results 269 patients (mean age 14±13 years, 47% male) underwent BA with the use of demucolised intestinal segments. Among the patients in the sample, 187 (69.52%) had neurogenic bladder, 68 (25.28%) had bladder exstrophy, nine had tuberculosis (3.34%), four had a posterior urethral valve (1.49%) and one with hypospadia (0.37%). After the surgical procedure, a significant increment in both urodynamic parameters was found, with a 222% increase in bladder capacity and 604% in bladder compliance (p <0.001 in both analyzes). Mean follow-up time ranged from 2 to 358 months, with a median of 72 months (IQR 74-247). Among all patients, 5 presented spontaneous perforation. Conclusion The study showed statistically significant increase in both compliance and bladder capacity after non-secretory BA, with a low rate of severe complications.Sociedade Brasileira de Urologia2019-08-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382019000400681International braz j urol v.45 n.4 2019reponame:International Braz J Urol (Online)instname:Sociedade Brasileira de Urologia (SBU)instacron:SBU10.1590/s1677-5538.ibju.2018.0595info:eu-repo/semantics/openAccessDantas,Rose A. F.Calisto,Fernanda C. F. S.Vilar,Fabio O.Araujo,Luiz A. P.Lima,Salvador V. C.eng2019-08-30T00:00:00Zoai:scielo:S1677-55382019000400681Revistahttp://www.brazjurol.com.br/ONGhttps://old.scielo.br/oai/scielo-oai.php||brazjurol@brazjurol.com.br1677-61191677-5538opendoar:2019-08-30T00:00International Braz J Urol (Online) - Sociedade Brasileira de Urologia (SBU)false
dc.title.none.fl_str_mv Nonsecretory intestinocystoplasty: postoperative outcomes of 25 years
title Nonsecretory intestinocystoplasty: postoperative outcomes of 25 years
spellingShingle Nonsecretory intestinocystoplasty: postoperative outcomes of 25 years
Dantas,Rose A. F.
Hypopituitarism
Urinary Bladder
Disease
title_short Nonsecretory intestinocystoplasty: postoperative outcomes of 25 years
title_full Nonsecretory intestinocystoplasty: postoperative outcomes of 25 years
title_fullStr Nonsecretory intestinocystoplasty: postoperative outcomes of 25 years
title_full_unstemmed Nonsecretory intestinocystoplasty: postoperative outcomes of 25 years
title_sort Nonsecretory intestinocystoplasty: postoperative outcomes of 25 years
author Dantas,Rose A. F.
author_facet Dantas,Rose A. F.
Calisto,Fernanda C. F. S.
Vilar,Fabio O.
Araujo,Luiz A. P.
Lima,Salvador V. C.
author_role author
author2 Calisto,Fernanda C. F. S.
Vilar,Fabio O.
Araujo,Luiz A. P.
Lima,Salvador V. C.
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Dantas,Rose A. F.
Calisto,Fernanda C. F. S.
Vilar,Fabio O.
Araujo,Luiz A. P.
Lima,Salvador V. C.
dc.subject.por.fl_str_mv Hypopituitarism
Urinary Bladder
Disease
topic Hypopituitarism
Urinary Bladder
Disease
description ABSTRACT Objective The objective of bladder augmentation (BA) is to create a low-pressure reservoir with adequate capacity. Despite its benefits, the use of intestinal patches in bladder enlargement provides a high risk of developing complications and BA with demucosalised bowel represents a potential alternative. Therefore, this study evaluated urological parameters and long-term clinical follow-up of patients submitted to non-secretory BA in a single center with 25 years of experience. Materials and Methods Patients treated with BA underwent urological evaluation, which included history, physical examination and urodynamic study. The main urodynamic parameters (bladder capacity and bladder compliance) were assessed in the pre and postoperative moments, and compared by the Wilcoxon Signed Rank test. The main long-term complications were described. Results 269 patients (mean age 14±13 years, 47% male) underwent BA with the use of demucolised intestinal segments. Among the patients in the sample, 187 (69.52%) had neurogenic bladder, 68 (25.28%) had bladder exstrophy, nine had tuberculosis (3.34%), four had a posterior urethral valve (1.49%) and one with hypospadia (0.37%). After the surgical procedure, a significant increment in both urodynamic parameters was found, with a 222% increase in bladder capacity and 604% in bladder compliance (p <0.001 in both analyzes). Mean follow-up time ranged from 2 to 358 months, with a median of 72 months (IQR 74-247). Among all patients, 5 presented spontaneous perforation. Conclusion The study showed statistically significant increase in both compliance and bladder capacity after non-secretory BA, with a low rate of severe complications.
publishDate 2019
dc.date.none.fl_str_mv 2019-08-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382019000400681
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dc.language.iso.fl_str_mv eng
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dc.relation.none.fl_str_mv 10.1590/s1677-5538.ibju.2018.0595
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dc.publisher.none.fl_str_mv Sociedade Brasileira de Urologia
publisher.none.fl_str_mv Sociedade Brasileira de Urologia
dc.source.none.fl_str_mv International braz j urol v.45 n.4 2019
reponame:International Braz J Urol (Online)
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reponame_str International Braz J Urol (Online)
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