Testicular mixed germ cell tumor presenting with seizure as the initial symptom: a case report and literature review
Autor(a) principal: | |
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Data de Publicação: | 2019 |
Outros Autores: | , |
Tipo de documento: | Relatório |
Idioma: | eng |
Título da fonte: | International Braz J Urol (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382019000300629 |
Resumo: | Abstract Most patients with testicular germ cell tumor present with a painless scrotal mass. We report a 19-year-old patient who presented with neurological complains. Rapid clinical progression to coma was noted during the staging work up. A diagnosis of testicular mixed germ cell tumor with multiorgan metastasis (lymph node, lung, liver and brain) was made. Patients with brain metastasis should receive chemotherapy alone or combined with surgery or radiotherapy. Because the clinical symptoms deteriorated quickly, surgery was used upfront followed by chemotherapy and radiotherapy for the brain tumor. After the first stage of treatment, the clinical symptoms, tumor markers and imaging findings were improved. The residual brain tumor was eliminated by chemotherapy, and only sparse degenerated tumor cells were noted in the brain tissue. Longer follow up is required to assess the impact of our treatment strategy. |
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Testicular mixed germ cell tumor presenting with seizure as the initial symptom: a case report and literature reviewTestisTesticular Germ Cell Tumor 1 [Supplementary Concept]Neoplasm MetastasisAbstract Most patients with testicular germ cell tumor present with a painless scrotal mass. We report a 19-year-old patient who presented with neurological complains. Rapid clinical progression to coma was noted during the staging work up. A diagnosis of testicular mixed germ cell tumor with multiorgan metastasis (lymph node, lung, liver and brain) was made. Patients with brain metastasis should receive chemotherapy alone or combined with surgery or radiotherapy. Because the clinical symptoms deteriorated quickly, surgery was used upfront followed by chemotherapy and radiotherapy for the brain tumor. After the first stage of treatment, the clinical symptoms, tumor markers and imaging findings were improved. The residual brain tumor was eliminated by chemotherapy, and only sparse degenerated tumor cells were noted in the brain tissue. Longer follow up is required to assess the impact of our treatment strategy.Sociedade Brasileira de Urologia2019-06-01info:eu-repo/semantics/reportinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382019000300629International braz j urol v.45 n.3 2019reponame:International Braz J Urol (Online)instname:Sociedade Brasileira de Urologia (SBU)instacron:SBU10.1590/s1677-5538.ibju.2018.0523info:eu-repo/semantics/openAccessSyu,Syuan-HaoChang,Chia-LunShih,Hung-Jeneng2019-06-18T00:00:00Zoai:scielo:S1677-55382019000300629Revistahttp://www.brazjurol.com.br/ONGhttps://old.scielo.br/oai/scielo-oai.php||brazjurol@brazjurol.com.br1677-61191677-5538opendoar:2019-06-18T00:00International Braz J Urol (Online) - Sociedade Brasileira de Urologia (SBU)false |
dc.title.none.fl_str_mv |
Testicular mixed germ cell tumor presenting with seizure as the initial symptom: a case report and literature review |
title |
Testicular mixed germ cell tumor presenting with seizure as the initial symptom: a case report and literature review |
spellingShingle |
Testicular mixed germ cell tumor presenting with seizure as the initial symptom: a case report and literature review Syu,Syuan-Hao Testis Testicular Germ Cell Tumor 1 [Supplementary Concept] Neoplasm Metastasis |
title_short |
Testicular mixed germ cell tumor presenting with seizure as the initial symptom: a case report and literature review |
title_full |
Testicular mixed germ cell tumor presenting with seizure as the initial symptom: a case report and literature review |
title_fullStr |
Testicular mixed germ cell tumor presenting with seizure as the initial symptom: a case report and literature review |
title_full_unstemmed |
Testicular mixed germ cell tumor presenting with seizure as the initial symptom: a case report and literature review |
title_sort |
Testicular mixed germ cell tumor presenting with seizure as the initial symptom: a case report and literature review |
author |
Syu,Syuan-Hao |
author_facet |
Syu,Syuan-Hao Chang,Chia-Lun Shih,Hung-Jen |
author_role |
author |
author2 |
Chang,Chia-Lun Shih,Hung-Jen |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
Syu,Syuan-Hao Chang,Chia-Lun Shih,Hung-Jen |
dc.subject.por.fl_str_mv |
Testis Testicular Germ Cell Tumor 1 [Supplementary Concept] Neoplasm Metastasis |
topic |
Testis Testicular Germ Cell Tumor 1 [Supplementary Concept] Neoplasm Metastasis |
description |
Abstract Most patients with testicular germ cell tumor present with a painless scrotal mass. We report a 19-year-old patient who presented with neurological complains. Rapid clinical progression to coma was noted during the staging work up. A diagnosis of testicular mixed germ cell tumor with multiorgan metastasis (lymph node, lung, liver and brain) was made. Patients with brain metastasis should receive chemotherapy alone or combined with surgery or radiotherapy. Because the clinical symptoms deteriorated quickly, surgery was used upfront followed by chemotherapy and radiotherapy for the brain tumor. After the first stage of treatment, the clinical symptoms, tumor markers and imaging findings were improved. The residual brain tumor was eliminated by chemotherapy, and only sparse degenerated tumor cells were noted in the brain tissue. Longer follow up is required to assess the impact of our treatment strategy. |
publishDate |
2019 |
dc.date.none.fl_str_mv |
2019-06-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/report |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
report |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382019000300629 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382019000300629 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/s1677-5538.ibju.2018.0523 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Urologia |
publisher.none.fl_str_mv |
Sociedade Brasileira de Urologia |
dc.source.none.fl_str_mv |
International braz j urol v.45 n.3 2019 reponame:International Braz J Urol (Online) instname:Sociedade Brasileira de Urologia (SBU) instacron:SBU |
instname_str |
Sociedade Brasileira de Urologia (SBU) |
instacron_str |
SBU |
institution |
SBU |
reponame_str |
International Braz J Urol (Online) |
collection |
International Braz J Urol (Online) |
repository.name.fl_str_mv |
International Braz J Urol (Online) - Sociedade Brasileira de Urologia (SBU) |
repository.mail.fl_str_mv |
||brazjurol@brazjurol.com.br |
_version_ |
1750318076849553408 |