Urethral pressure variation: a neglected contributing factor in patients with overactive bladder syndrome?

Detalhes bibliográficos
Autor(a) principal: Kirschner-Hermanns,Ruth
Data de Publicação: 2017
Outros Autores: Anding,Ralf, Gadzhiev,Nariman, Goping,Ing, Campbell,Adele, Huppertz,Nadine
Tipo de documento: Artigo
Idioma: eng
Título da fonte: International Braz J Urol (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382017000200272
Resumo: ABSTRACT Objective To study urethral pressure variations during the whole filling phase among different groups of patients. Material and Methods We investigated 79 consecutive patients from January 2011 to June 2012. All patients were recruited within our routine practice in our continence clinic and were evaluated with urodynamic exam according to the standards of the International Continence Society (ICS) with an additional continuous measurement of the urethral pressure profile (cUPP) that was done in a supine position. Patients with genital prolapse >grade I, as well as patients with impaired cognitive function or neurogenic disorders were excluded. Bacteriuria at the time of investigation was excluded by urine analysis. Urethral pressure changes higher than 15cmH2O were considered as ‘urethral instability’. Results From 79 investigated patients, 29 were clinically diagnosed with OAB syndrome, 19 with stress urinary incontinence (SUI) and 31 with mixed (OAB and SUI) incontinence. The prevalence of ‘urethral instability’ as defined in this study was 54.4% (43/79). The mean Δp in patients with OAB (36.5cmH2O) was significantly higher (p<0.05) than in groups with pure stress (14.9cmH2O) and mixed urinary incontinence (19.3cmH2O). Conclusions Etiology of ‘urethral instability’ is unknown, but high prevalence among patients with overactive bladder syndrome, especially concomitant with detrusor activity can raise a fair question and direct further diagnostic as well as treatment efforts.
id SBU-1_8fea20f7b366b28f380bcbce1a39274d
oai_identifier_str oai:scielo:S1677-55382017000200272
network_acronym_str SBU-1
network_name_str International Braz J Urol (Online)
repository_id_str
spelling Urethral pressure variation: a neglected contributing factor in patients with overactive bladder syndrome?Urinary Bladder, OveractiveUrodynamicsUrethraABSTRACT Objective To study urethral pressure variations during the whole filling phase among different groups of patients. Material and Methods We investigated 79 consecutive patients from January 2011 to June 2012. All patients were recruited within our routine practice in our continence clinic and were evaluated with urodynamic exam according to the standards of the International Continence Society (ICS) with an additional continuous measurement of the urethral pressure profile (cUPP) that was done in a supine position. Patients with genital prolapse >grade I, as well as patients with impaired cognitive function or neurogenic disorders were excluded. Bacteriuria at the time of investigation was excluded by urine analysis. Urethral pressure changes higher than 15cmH2O were considered as ‘urethral instability’. Results From 79 investigated patients, 29 were clinically diagnosed with OAB syndrome, 19 with stress urinary incontinence (SUI) and 31 with mixed (OAB and SUI) incontinence. The prevalence of ‘urethral instability’ as defined in this study was 54.4% (43/79). The mean Δp in patients with OAB (36.5cmH2O) was significantly higher (p<0.05) than in groups with pure stress (14.9cmH2O) and mixed urinary incontinence (19.3cmH2O). Conclusions Etiology of ‘urethral instability’ is unknown, but high prevalence among patients with overactive bladder syndrome, especially concomitant with detrusor activity can raise a fair question and direct further diagnostic as well as treatment efforts.Sociedade Brasileira de Urologia2017-04-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382017000200272International braz j urol v.43 n.2 2017reponame:International Braz J Urol (Online)instname:Sociedade Brasileira de Urologia (SBU)instacron:SBU10.1590/s1677-5538.ibju.2016.0308info:eu-repo/semantics/openAccessKirschner-Hermanns,RuthAnding,RalfGadzhiev,NarimanGoping,IngCampbell,AdeleHuppertz,Nadineeng2017-04-11T00:00:00Zoai:scielo:S1677-55382017000200272Revistahttp://www.brazjurol.com.br/ONGhttps://old.scielo.br/oai/scielo-oai.php||brazjurol@brazjurol.com.br1677-61191677-5538opendoar:2017-04-11T00:00International Braz J Urol (Online) - Sociedade Brasileira de Urologia (SBU)false
dc.title.none.fl_str_mv Urethral pressure variation: a neglected contributing factor in patients with overactive bladder syndrome?
title Urethral pressure variation: a neglected contributing factor in patients with overactive bladder syndrome?
spellingShingle Urethral pressure variation: a neglected contributing factor in patients with overactive bladder syndrome?
Kirschner-Hermanns,Ruth
Urinary Bladder, Overactive
Urodynamics
Urethra
title_short Urethral pressure variation: a neglected contributing factor in patients with overactive bladder syndrome?
title_full Urethral pressure variation: a neglected contributing factor in patients with overactive bladder syndrome?
title_fullStr Urethral pressure variation: a neglected contributing factor in patients with overactive bladder syndrome?
title_full_unstemmed Urethral pressure variation: a neglected contributing factor in patients with overactive bladder syndrome?
title_sort Urethral pressure variation: a neglected contributing factor in patients with overactive bladder syndrome?
author Kirschner-Hermanns,Ruth
author_facet Kirschner-Hermanns,Ruth
Anding,Ralf
Gadzhiev,Nariman
Goping,Ing
Campbell,Adele
Huppertz,Nadine
author_role author
author2 Anding,Ralf
Gadzhiev,Nariman
Goping,Ing
Campbell,Adele
Huppertz,Nadine
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Kirschner-Hermanns,Ruth
Anding,Ralf
Gadzhiev,Nariman
Goping,Ing
Campbell,Adele
Huppertz,Nadine
dc.subject.por.fl_str_mv Urinary Bladder, Overactive
Urodynamics
Urethra
topic Urinary Bladder, Overactive
Urodynamics
Urethra
description ABSTRACT Objective To study urethral pressure variations during the whole filling phase among different groups of patients. Material and Methods We investigated 79 consecutive patients from January 2011 to June 2012. All patients were recruited within our routine practice in our continence clinic and were evaluated with urodynamic exam according to the standards of the International Continence Society (ICS) with an additional continuous measurement of the urethral pressure profile (cUPP) that was done in a supine position. Patients with genital prolapse >grade I, as well as patients with impaired cognitive function or neurogenic disorders were excluded. Bacteriuria at the time of investigation was excluded by urine analysis. Urethral pressure changes higher than 15cmH2O were considered as ‘urethral instability’. Results From 79 investigated patients, 29 were clinically diagnosed with OAB syndrome, 19 with stress urinary incontinence (SUI) and 31 with mixed (OAB and SUI) incontinence. The prevalence of ‘urethral instability’ as defined in this study was 54.4% (43/79). The mean Δp in patients with OAB (36.5cmH2O) was significantly higher (p<0.05) than in groups with pure stress (14.9cmH2O) and mixed urinary incontinence (19.3cmH2O). Conclusions Etiology of ‘urethral instability’ is unknown, but high prevalence among patients with overactive bladder syndrome, especially concomitant with detrusor activity can raise a fair question and direct further diagnostic as well as treatment efforts.
publishDate 2017
dc.date.none.fl_str_mv 2017-04-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382017000200272
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382017000200272
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/s1677-5538.ibju.2016.0308
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Urologia
publisher.none.fl_str_mv Sociedade Brasileira de Urologia
dc.source.none.fl_str_mv International braz j urol v.43 n.2 2017
reponame:International Braz J Urol (Online)
instname:Sociedade Brasileira de Urologia (SBU)
instacron:SBU
instname_str Sociedade Brasileira de Urologia (SBU)
instacron_str SBU
institution SBU
reponame_str International Braz J Urol (Online)
collection International Braz J Urol (Online)
repository.name.fl_str_mv International Braz J Urol (Online) - Sociedade Brasileira de Urologia (SBU)
repository.mail.fl_str_mv ||brazjurol@brazjurol.com.br
_version_ 1750318075421392896