Tadalafil rehabilitation therapy preserves penile size after bilateral nerve sparing radical retropubic prostatectomy

Detalhes bibliográficos
Autor(a) principal: Aydogdu,Ozgu
Data de Publicação: 2011
Outros Autores: Gokce,Mehmet Ilker, Burgu,Berk, Baltaci,Sumer, Yaman,Onder
Tipo de documento: Artigo
Idioma: eng
Título da fonte: International Braz J Urol (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382011000300007
Resumo: OBJECTIVE: To evaluate the change in penile size r bilateral nerve sparing retropubic radical prostatectomy (BNSRRP) and possible effect of Tadalafil. MATERIALS AND METHODS: A total of 65 patients underwent BNSRRP and they were evaluated prospectively for a whole year of follow-up . The patients were randomized to control without rehabilitation (Group 1) or Tadalafil rehabilitation group (Group 2). The patients were evaluated at months 3, 6 and 12 postoperatively for erectile function, penile measurements (flaccid penile length, penile length at maximum erection, penile circumference at flaccid status, and penile circumference at maximum erection), penile abnormalities and general health status. Statistical analysis was performed by Chi-Square test and significance was defined as p value < 0.05. RESULTS: In Group 1 there was significant decrease in penile measurements at month 3 compared to preoperative measurements. There was decrease in all parameters at month 6 compared to month 3 but only the decrease in penile length at maximum erection was significant. There were no significant differences between postoperative months 6 and 12 for all measurements. In Group 2 there was a tendency to decrease in all measurements at month 3 compared to baseline. There was no significant difference for penile measurements between postoperative 3rd and 6th months and between 6th month and the first year. CONCLUSION: Although further large sampled trials are needed to describe the possible positive effect of tadalafil or other PDE5-I's on penile size after BNSRRP, tadalafil rehabilitation is effective in preserving penile size especially in the early postoperative period after BNSRRP.
id SBU-1_a632e0cf34c5a4b9d74f471ec9f96d08
oai_identifier_str oai:scielo:S1677-55382011000300007
network_acronym_str SBU-1
network_name_str International Braz J Urol (Online)
repository_id_str
spelling Tadalafil rehabilitation therapy preserves penile size after bilateral nerve sparing radical retropubic prostatectomyPenileerectileprostatectomyerectile dysfunctiontadalafilOBJECTIVE: To evaluate the change in penile size r bilateral nerve sparing retropubic radical prostatectomy (BNSRRP) and possible effect of Tadalafil. MATERIALS AND METHODS: A total of 65 patients underwent BNSRRP and they were evaluated prospectively for a whole year of follow-up . The patients were randomized to control without rehabilitation (Group 1) or Tadalafil rehabilitation group (Group 2). The patients were evaluated at months 3, 6 and 12 postoperatively for erectile function, penile measurements (flaccid penile length, penile length at maximum erection, penile circumference at flaccid status, and penile circumference at maximum erection), penile abnormalities and general health status. Statistical analysis was performed by Chi-Square test and significance was defined as p value < 0.05. RESULTS: In Group 1 there was significant decrease in penile measurements at month 3 compared to preoperative measurements. There was decrease in all parameters at month 6 compared to month 3 but only the decrease in penile length at maximum erection was significant. There were no significant differences between postoperative months 6 and 12 for all measurements. In Group 2 there was a tendency to decrease in all measurements at month 3 compared to baseline. There was no significant difference for penile measurements between postoperative 3rd and 6th months and between 6th month and the first year. CONCLUSION: Although further large sampled trials are needed to describe the possible positive effect of tadalafil or other PDE5-I's on penile size after BNSRRP, tadalafil rehabilitation is effective in preserving penile size especially in the early postoperative period after BNSRRP.Sociedade Brasileira de Urologia2011-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382011000300007International braz j urol v.37 n.3 2011reponame:International Braz J Urol (Online)instname:Sociedade Brasileira de Urologia (SBU)instacron:SBU10.1590/S1677-55382011000300007info:eu-repo/semantics/openAccessAydogdu,OzguGokce,Mehmet IlkerBurgu,BerkBaltaci,SumerYaman,Ondereng2011-07-27T00:00:00Zoai:scielo:S1677-55382011000300007Revistahttp://www.brazjurol.com.br/ONGhttps://old.scielo.br/oai/scielo-oai.php||brazjurol@brazjurol.com.br1677-61191677-5538opendoar:2011-07-27T00:00International Braz J Urol (Online) - Sociedade Brasileira de Urologia (SBU)false
dc.title.none.fl_str_mv Tadalafil rehabilitation therapy preserves penile size after bilateral nerve sparing radical retropubic prostatectomy
title Tadalafil rehabilitation therapy preserves penile size after bilateral nerve sparing radical retropubic prostatectomy
spellingShingle Tadalafil rehabilitation therapy preserves penile size after bilateral nerve sparing radical retropubic prostatectomy
Aydogdu,Ozgu
Penile
erectile
prostatectomy
erectile dysfunction
tadalafil
title_short Tadalafil rehabilitation therapy preserves penile size after bilateral nerve sparing radical retropubic prostatectomy
title_full Tadalafil rehabilitation therapy preserves penile size after bilateral nerve sparing radical retropubic prostatectomy
title_fullStr Tadalafil rehabilitation therapy preserves penile size after bilateral nerve sparing radical retropubic prostatectomy
title_full_unstemmed Tadalafil rehabilitation therapy preserves penile size after bilateral nerve sparing radical retropubic prostatectomy
title_sort Tadalafil rehabilitation therapy preserves penile size after bilateral nerve sparing radical retropubic prostatectomy
author Aydogdu,Ozgu
author_facet Aydogdu,Ozgu
Gokce,Mehmet Ilker
Burgu,Berk
Baltaci,Sumer
Yaman,Onder
author_role author
author2 Gokce,Mehmet Ilker
Burgu,Berk
Baltaci,Sumer
Yaman,Onder
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Aydogdu,Ozgu
Gokce,Mehmet Ilker
Burgu,Berk
Baltaci,Sumer
Yaman,Onder
dc.subject.por.fl_str_mv Penile
erectile
prostatectomy
erectile dysfunction
tadalafil
topic Penile
erectile
prostatectomy
erectile dysfunction
tadalafil
description OBJECTIVE: To evaluate the change in penile size r bilateral nerve sparing retropubic radical prostatectomy (BNSRRP) and possible effect of Tadalafil. MATERIALS AND METHODS: A total of 65 patients underwent BNSRRP and they were evaluated prospectively for a whole year of follow-up . The patients were randomized to control without rehabilitation (Group 1) or Tadalafil rehabilitation group (Group 2). The patients were evaluated at months 3, 6 and 12 postoperatively for erectile function, penile measurements (flaccid penile length, penile length at maximum erection, penile circumference at flaccid status, and penile circumference at maximum erection), penile abnormalities and general health status. Statistical analysis was performed by Chi-Square test and significance was defined as p value < 0.05. RESULTS: In Group 1 there was significant decrease in penile measurements at month 3 compared to preoperative measurements. There was decrease in all parameters at month 6 compared to month 3 but only the decrease in penile length at maximum erection was significant. There were no significant differences between postoperative months 6 and 12 for all measurements. In Group 2 there was a tendency to decrease in all measurements at month 3 compared to baseline. There was no significant difference for penile measurements between postoperative 3rd and 6th months and between 6th month and the first year. CONCLUSION: Although further large sampled trials are needed to describe the possible positive effect of tadalafil or other PDE5-I's on penile size after BNSRRP, tadalafil rehabilitation is effective in preserving penile size especially in the early postoperative period after BNSRRP.
publishDate 2011
dc.date.none.fl_str_mv 2011-06-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382011000300007
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382011000300007
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1677-55382011000300007
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Urologia
publisher.none.fl_str_mv Sociedade Brasileira de Urologia
dc.source.none.fl_str_mv International braz j urol v.37 n.3 2011
reponame:International Braz J Urol (Online)
instname:Sociedade Brasileira de Urologia (SBU)
instacron:SBU
instname_str Sociedade Brasileira de Urologia (SBU)
instacron_str SBU
institution SBU
reponame_str International Braz J Urol (Online)
collection International Braz J Urol (Online)
repository.name.fl_str_mv International Braz J Urol (Online) - Sociedade Brasileira de Urologia (SBU)
repository.mail.fl_str_mv ||brazjurol@brazjurol.com.br
_version_ 1750318072312365056