Low-dose-rate brachytherapy for patients with transurethral resection before implantation in prostate cancer. Long-term results
Autor(a) principal: | |
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Data de Publicação: | 2016 |
Outros Autores: | , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | International Braz J Urol (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382016000100047 |
Resumo: | ABSTRACT Objectives We analyzed the long-term oncologic outcome for patients with prostate cancer and transurethral resection who were treated using low-dose-rate (LDR) prostate brachytherapy. Methods and Materials From January 2001 to December 2005, 57 consecutive patients were treated with clinically localized prostate cancer. No patients received external beam radiation. All of them underwent LDR prostate brachytherapy. Biochemical failure was defined according to the “Phoenix consensus”. Patients were stratified as low and intermediate risk based on The Memorial Sloan Kettering group definition. Results The median follow-up time for these 57 patients was 104 months. The overall survival according to Kaplan-Meier estimates was 88% (±6%) at 5 years and 77% (±6%) at 12 years. The 5 and 10 years for failure in tumour-free survival (TFS) was 96% and respectively (±2%), whereas for biochemical control was 94% and respectively (±3%) at 5 and 10 years, 98% (±1%) of patients being free of local recurrence. A patient reported incontinence after treatment (1.7%). The chronic genitourinary complains grade I were 7% and grade II, 10%. At six months 94% of patients reported no change in bowel function. Conclusions The excellent long-term results and low morbidity presented, as well as the many advantages of prostate brachytherapy over other treatments, demonstrates that brachytherapy is an effective treatment for patients with transurethral resection and clinical organ-confined prostate cancer. |
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International Braz J Urol (Online) |
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Low-dose-rate brachytherapy for patients with transurethral resection before implantation in prostate cancer. Long-term resultsBrachytherapyTransurethral Resection of ProstateProstatic NeoplasmsABSTRACT Objectives We analyzed the long-term oncologic outcome for patients with prostate cancer and transurethral resection who were treated using low-dose-rate (LDR) prostate brachytherapy. Methods and Materials From January 2001 to December 2005, 57 consecutive patients were treated with clinically localized prostate cancer. No patients received external beam radiation. All of them underwent LDR prostate brachytherapy. Biochemical failure was defined according to the “Phoenix consensus”. Patients were stratified as low and intermediate risk based on The Memorial Sloan Kettering group definition. Results The median follow-up time for these 57 patients was 104 months. The overall survival according to Kaplan-Meier estimates was 88% (±6%) at 5 years and 77% (±6%) at 12 years. The 5 and 10 years for failure in tumour-free survival (TFS) was 96% and respectively (±2%), whereas for biochemical control was 94% and respectively (±3%) at 5 and 10 years, 98% (±1%) of patients being free of local recurrence. A patient reported incontinence after treatment (1.7%). The chronic genitourinary complains grade I were 7% and grade II, 10%. At six months 94% of patients reported no change in bowel function. Conclusions The excellent long-term results and low morbidity presented, as well as the many advantages of prostate brachytherapy over other treatments, demonstrates that brachytherapy is an effective treatment for patients with transurethral resection and clinical organ-confined prostate cancer.Sociedade Brasileira de Urologia2016-02-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382016000100047International braz j urol v.42 n.1 2016reponame:International Braz J Urol (Online)instname:Sociedade Brasileira de Urologia (SBU)instacron:SBU10.1590/S1677-5538.IBJU.2014.0531info:eu-repo/semantics/openAccessPrada,Pedro J.Anchuelo,JavierBlanco,Ana GarcíaPayá,GemaCardenal,JuanAcuña,EnriqueFerri,MaríaVázquez,AndrésPacheco,MaiteSanchez,Jesicaeng2016-03-28T00:00:00Zoai:scielo:S1677-55382016000100047Revistahttp://www.brazjurol.com.br/ONGhttps://old.scielo.br/oai/scielo-oai.php||brazjurol@brazjurol.com.br1677-61191677-5538opendoar:2016-03-28T00:00International Braz J Urol (Online) - Sociedade Brasileira de Urologia (SBU)false |
dc.title.none.fl_str_mv |
Low-dose-rate brachytherapy for patients with transurethral resection before implantation in prostate cancer. Long-term results |
title |
Low-dose-rate brachytherapy for patients with transurethral resection before implantation in prostate cancer. Long-term results |
spellingShingle |
Low-dose-rate brachytherapy for patients with transurethral resection before implantation in prostate cancer. Long-term results Prada,Pedro J. Brachytherapy Transurethral Resection of Prostate Prostatic Neoplasms |
title_short |
Low-dose-rate brachytherapy for patients with transurethral resection before implantation in prostate cancer. Long-term results |
title_full |
Low-dose-rate brachytherapy for patients with transurethral resection before implantation in prostate cancer. Long-term results |
title_fullStr |
Low-dose-rate brachytherapy for patients with transurethral resection before implantation in prostate cancer. Long-term results |
title_full_unstemmed |
Low-dose-rate brachytherapy for patients with transurethral resection before implantation in prostate cancer. Long-term results |
title_sort |
Low-dose-rate brachytherapy for patients with transurethral resection before implantation in prostate cancer. Long-term results |
author |
Prada,Pedro J. |
author_facet |
Prada,Pedro J. Anchuelo,Javier Blanco,Ana García Payá,Gema Cardenal,Juan Acuña,Enrique Ferri,María Vázquez,Andrés Pacheco,Maite Sanchez,Jesica |
author_role |
author |
author2 |
Anchuelo,Javier Blanco,Ana García Payá,Gema Cardenal,Juan Acuña,Enrique Ferri,María Vázquez,Andrés Pacheco,Maite Sanchez,Jesica |
author2_role |
author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Prada,Pedro J. Anchuelo,Javier Blanco,Ana García Payá,Gema Cardenal,Juan Acuña,Enrique Ferri,María Vázquez,Andrés Pacheco,Maite Sanchez,Jesica |
dc.subject.por.fl_str_mv |
Brachytherapy Transurethral Resection of Prostate Prostatic Neoplasms |
topic |
Brachytherapy Transurethral Resection of Prostate Prostatic Neoplasms |
description |
ABSTRACT Objectives We analyzed the long-term oncologic outcome for patients with prostate cancer and transurethral resection who were treated using low-dose-rate (LDR) prostate brachytherapy. Methods and Materials From January 2001 to December 2005, 57 consecutive patients were treated with clinically localized prostate cancer. No patients received external beam radiation. All of them underwent LDR prostate brachytherapy. Biochemical failure was defined according to the “Phoenix consensus”. Patients were stratified as low and intermediate risk based on The Memorial Sloan Kettering group definition. Results The median follow-up time for these 57 patients was 104 months. The overall survival according to Kaplan-Meier estimates was 88% (±6%) at 5 years and 77% (±6%) at 12 years. The 5 and 10 years for failure in tumour-free survival (TFS) was 96% and respectively (±2%), whereas for biochemical control was 94% and respectively (±3%) at 5 and 10 years, 98% (±1%) of patients being free of local recurrence. A patient reported incontinence after treatment (1.7%). The chronic genitourinary complains grade I were 7% and grade II, 10%. At six months 94% of patients reported no change in bowel function. Conclusions The excellent long-term results and low morbidity presented, as well as the many advantages of prostate brachytherapy over other treatments, demonstrates that brachytherapy is an effective treatment for patients with transurethral resection and clinical organ-confined prostate cancer. |
publishDate |
2016 |
dc.date.none.fl_str_mv |
2016-02-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382016000100047 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382016000100047 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S1677-5538.IBJU.2014.0531 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Urologia |
publisher.none.fl_str_mv |
Sociedade Brasileira de Urologia |
dc.source.none.fl_str_mv |
International braz j urol v.42 n.1 2016 reponame:International Braz J Urol (Online) instname:Sociedade Brasileira de Urologia (SBU) instacron:SBU |
instname_str |
Sociedade Brasileira de Urologia (SBU) |
instacron_str |
SBU |
institution |
SBU |
reponame_str |
International Braz J Urol (Online) |
collection |
International Braz J Urol (Online) |
repository.name.fl_str_mv |
International Braz J Urol (Online) - Sociedade Brasileira de Urologia (SBU) |
repository.mail.fl_str_mv |
||brazjurol@brazjurol.com.br |
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1750318074558414848 |