Complete response of metastatic renal cancer with dendritic cell vaccine
Autor(a) principal: | |
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Data de Publicação: | 2003 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | International Braz J Urol (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382003000600006 |
Resumo: | INTRODUCTION: We report a case of metastatic renal cell carcinoma that presented involution following therapy with dendritic cells. CASE REPORT: Male, 51-year old patient underwent left radical nephrectomy in September 1999 due to renal cell carcinoma, evolved with recurrence of the neoplasia in January 2002, confirmed by resection of the lesion. A vaccine therapy based on dendritic cells was then performed during 5 months (4 applications). After this period, there was occurrence of new lesions, whose resection revealed areas of necrosis and inflammatory infiltrate. DISCUSSION: The outcome of renal cell carcinoma is influenced by prognostic factors that confer more aggressive tumor characteristics. However, in cases of recurrence, the systemic therapy with dendritic cells-based vaccine can be associated with a better outcome with regression of disease. |
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International Braz J Urol (Online) |
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Complete response of metastatic renal cancer with dendritic cell vaccinekidney neoplasmscarcinomaneoplasms metastasisdendritic cellvaccinesINTRODUCTION: We report a case of metastatic renal cell carcinoma that presented involution following therapy with dendritic cells. CASE REPORT: Male, 51-year old patient underwent left radical nephrectomy in September 1999 due to renal cell carcinoma, evolved with recurrence of the neoplasia in January 2002, confirmed by resection of the lesion. A vaccine therapy based on dendritic cells was then performed during 5 months (4 applications). After this period, there was occurrence of new lesions, whose resection revealed areas of necrosis and inflammatory infiltrate. DISCUSSION: The outcome of renal cell carcinoma is influenced by prognostic factors that confer more aggressive tumor characteristics. However, in cases of recurrence, the systemic therapy with dendritic cells-based vaccine can be associated with a better outcome with regression of disease.Sociedade Brasileira de Urologia2003-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382003000600006International braz j urol v.29 n.6 2003reponame:International Braz J Urol (Online)instname:Sociedade Brasileira de Urologia (SBU)instacron:SBU10.1590/S1677-55382003000600006info:eu-repo/semantics/openAccessDall'Oglio,MarcosSrougi,MiguelBarbuto,José A.M.eng2004-05-07T00:00:00Zoai:scielo:S1677-55382003000600006Revistahttp://www.brazjurol.com.br/ONGhttps://old.scielo.br/oai/scielo-oai.php||brazjurol@brazjurol.com.br1677-61191677-5538opendoar:2004-05-07T00:00International Braz J Urol (Online) - Sociedade Brasileira de Urologia (SBU)false |
dc.title.none.fl_str_mv |
Complete response of metastatic renal cancer with dendritic cell vaccine |
title |
Complete response of metastatic renal cancer with dendritic cell vaccine |
spellingShingle |
Complete response of metastatic renal cancer with dendritic cell vaccine Dall'Oglio,Marcos kidney neoplasms carcinoma neoplasms metastasis dendritic cell vaccines |
title_short |
Complete response of metastatic renal cancer with dendritic cell vaccine |
title_full |
Complete response of metastatic renal cancer with dendritic cell vaccine |
title_fullStr |
Complete response of metastatic renal cancer with dendritic cell vaccine |
title_full_unstemmed |
Complete response of metastatic renal cancer with dendritic cell vaccine |
title_sort |
Complete response of metastatic renal cancer with dendritic cell vaccine |
author |
Dall'Oglio,Marcos |
author_facet |
Dall'Oglio,Marcos Srougi,Miguel Barbuto,José A.M. |
author_role |
author |
author2 |
Srougi,Miguel Barbuto,José A.M. |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
Dall'Oglio,Marcos Srougi,Miguel Barbuto,José A.M. |
dc.subject.por.fl_str_mv |
kidney neoplasms carcinoma neoplasms metastasis dendritic cell vaccines |
topic |
kidney neoplasms carcinoma neoplasms metastasis dendritic cell vaccines |
description |
INTRODUCTION: We report a case of metastatic renal cell carcinoma that presented involution following therapy with dendritic cells. CASE REPORT: Male, 51-year old patient underwent left radical nephrectomy in September 1999 due to renal cell carcinoma, evolved with recurrence of the neoplasia in January 2002, confirmed by resection of the lesion. A vaccine therapy based on dendritic cells was then performed during 5 months (4 applications). After this period, there was occurrence of new lesions, whose resection revealed areas of necrosis and inflammatory infiltrate. DISCUSSION: The outcome of renal cell carcinoma is influenced by prognostic factors that confer more aggressive tumor characteristics. However, in cases of recurrence, the systemic therapy with dendritic cells-based vaccine can be associated with a better outcome with regression of disease. |
publishDate |
2003 |
dc.date.none.fl_str_mv |
2003-12-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382003000600006 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382003000600006 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S1677-55382003000600006 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Urologia |
publisher.none.fl_str_mv |
Sociedade Brasileira de Urologia |
dc.source.none.fl_str_mv |
International braz j urol v.29 n.6 2003 reponame:International Braz J Urol (Online) instname:Sociedade Brasileira de Urologia (SBU) instacron:SBU |
instname_str |
Sociedade Brasileira de Urologia (SBU) |
instacron_str |
SBU |
institution |
SBU |
reponame_str |
International Braz J Urol (Online) |
collection |
International Braz J Urol (Online) |
repository.name.fl_str_mv |
International Braz J Urol (Online) - Sociedade Brasileira de Urologia (SBU) |
repository.mail.fl_str_mv |
||brazjurol@brazjurol.com.br |
_version_ |
1750318068658077696 |